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Conference Paper: Novel substrate to study the effect of surface-associated peptide mobility and rigidity in modulating macrophage behavior

TitleNovel substrate to study the effect of surface-associated peptide mobility and rigidity in modulating macrophage behavior
Authors
Li, J.Phillips, J. M.Kao, W. J.
Issue Date2004
Citation
Transactions - 7th World Biomaterials Congress, 2004, p. 1318 How to Cite?
AbstractThe role of surface-immobilized RGD and PHSRN domain mobility and/or interpositional rigidity in modulating the macrophage behavior was discussed. MPEG-Ac 454 or 2K was used to reduce non-specific cell adhesion as well as to limit the mobility of surface linked peptides. The non-adhesiveness of the substrates was tested by fibroblast adhesion assay. The purity of MPEG-Ac 2K approximated 98% and the yield was approximately 90%. PEG-Ac resulted with a conversion ratio approximating 80% and a yield approximating 15%.
Persistent Identifierhttp://hdl.handle.net/10722/216175

 

DC FieldValueLanguage
dc.contributor.authorLi, J.-
dc.contributor.authorPhillips, J. M.-
dc.contributor.authorKao, W. J.-
dc.date.accessioned2015-08-25T10:22:12Z-
dc.date.available2015-08-25T10:22:12Z-
dc.date.issued2004-
dc.identifier.citationTransactions - 7th World Biomaterials Congress, 2004, p. 1318-
dc.identifier.urihttp://hdl.handle.net/10722/216175-
dc.description.abstractThe role of surface-immobilized RGD and PHSRN domain mobility and/or interpositional rigidity in modulating the macrophage behavior was discussed. MPEG-Ac 454 or 2K was used to reduce non-specific cell adhesion as well as to limit the mobility of surface linked peptides. The non-adhesiveness of the substrates was tested by fibroblast adhesion assay. The purity of MPEG-Ac 2K approximated 98% and the yield was approximately 90%. PEG-Ac resulted with a conversion ratio approximating 80% and a yield approximating 15%.-
dc.languageeng-
dc.relation.ispartofTransactions - 7th World Biomaterials Congress-
dc.titleNovel substrate to study the effect of surface-associated peptide mobility and rigidity in modulating macrophage behavior-
dc.typeConference_Paper-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-13844275698-
dc.identifier.spage1318-
dc.identifier.epage1318-

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