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Article: MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph

TitleMEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph
Authors
Issue Date2015
Citation
Bioinformatics, 2015, v. 31 n. 10, p. 1674-1676 How to Cite?
AbstractSummary: MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252â Gbps in 44.1 and 99.6â h on a single computing node with and without a graphics processing unit, respectively. MEGAHIT assembles the data as a whole, i.e. no pre-processing like partitioning and normalization was needed. When compared with previous methods on assembling the soil data, MEGAHIT generated a three-time larger assembly, with longer contig N50 and average contig length; furthermore, 55.8% of the reads were aligned to the assembly, giving a fourfold improvement.
Persistent Identifierhttp://hdl.handle.net/10722/215513
ISSN
2017 Impact Factor: 5.481
2015 SCImago Journal Rankings: 4.643
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLI, D-
dc.contributor.authorLIU, CM-
dc.contributor.authorLUO, R-
dc.contributor.authorSadakane, K-
dc.contributor.authorLam, TW-
dc.date.accessioned2015-08-21T13:28:34Z-
dc.date.available2015-08-21T13:28:34Z-
dc.date.issued2015-
dc.identifier.citationBioinformatics, 2015, v. 31 n. 10, p. 1674-1676-
dc.identifier.issn1367-4803-
dc.identifier.urihttp://hdl.handle.net/10722/215513-
dc.description.abstractSummary: MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252â Gbps in 44.1 and 99.6â h on a single computing node with and without a graphics processing unit, respectively. MEGAHIT assembles the data as a whole, i.e. no pre-processing like partitioning and normalization was needed. When compared with previous methods on assembling the soil data, MEGAHIT generated a three-time larger assembly, with longer contig N50 and average contig length; furthermore, 55.8% of the reads were aligned to the assembly, giving a fourfold improvement.-
dc.languageeng-
dc.relation.ispartofBioinformatics-
dc.rightsThis is a pre-copy-editing, author-produced PDF of an article accepted for publication in [Bioinformatics] following peer review. The definitive publisher-authenticated version [2015, v. 31 n. 10, p. 1674-1676] is available online at: http://dx.doi.org/10.1093/bioinformatics/btv033-
dc.titleMEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph-
dc.typeArticle-
dc.identifier.emailLam, TW: twlam@cs.hku.hk-
dc.identifier.authorityLam, TW=rp00135-
dc.description.naturepostprint-
dc.identifier.doi10.1093/bioinformatics/btv033-
dc.identifier.pmid25609793-
dc.identifier.scopuseid_2-s2.0-84929626808-
dc.identifier.hkuros248451-
dc.identifier.volume31-
dc.identifier.issue10-
dc.identifier.spage1674-
dc.identifier.epage1676-
dc.identifier.isiWOS:000355672500023-

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