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Article: Stereotactic ablative radiotherapy for medically inoperable early stage lung cancer: early outcomes

TitleStereotactic ablative radiotherapy for medically inoperable early stage lung cancer: early outcomes
Authors
KeywordsLung neoplasms
Non-small-cell lung
Radiotherapy
Stereotaxic techniques
Survival rate
Carcinoma
Issue Date2012
Citation
Hong Kong Medical Journal, 2012, v. 18, n. 5, p. 412-418 How to Cite?
AbstractObjective To evaluate the clinical outcome and safety of stereotactic ablative radiotherapy for medically inoperable stage I non- small-cell lung carcinoma. Design Retrospective case series. Setting Pamela Youde Nethersole Eastern Hospital, Hong Kong. Patients All patients with medically inoperable stage I non-small-cell lung carcinoma receiving stereotactic ablative radiotherapy since its establishment in 2008. Main outcome measures Disease control rate, overall survival, and treatment toxicities. Results Sixteen stage I non-small-cell lung carcinoma patients underwent the procedure from June 2008 to November 2011. The median patient age was 82 years and the majority (81%) had moderate-tosevere co-morbidity based on the Adult Comorbidity Evaluation 27 index. With a median follow-up of 22 months, the 2-year primary tumour control rate, disease-free survival and overall survival rates were 91%, 71% and 87%, respectively. No grade 3 (National Cancer Institute Common Terminology Criteria for Adverse Events) or higher treatment-related complications were reported. Conclusion Stereotactic ablative radiotherapy can achieve a high degree of local control safely in medically inoperable patients with early lung cancer.
Persistent Identifierhttp://hdl.handle.net/10722/213986
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorChan, Oscar S H-
dc.contributor.authorYeung, Rebecca M W-
dc.contributor.authorHung, Albert W M-
dc.contributor.authorLee, Michael C H-
dc.contributor.authorChang, Amy T Y-
dc.contributor.authorChan, Connie C C-
dc.contributor.authorLee, Anne W M-
dc.date.accessioned2015-08-19T13:41:27Z-
dc.date.available2015-08-19T13:41:27Z-
dc.date.issued2012-
dc.identifier.citationHong Kong Medical Journal, 2012, v. 18, n. 5, p. 412-418-
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/213986-
dc.description.abstractObjective To evaluate the clinical outcome and safety of stereotactic ablative radiotherapy for medically inoperable stage I non- small-cell lung carcinoma. Design Retrospective case series. Setting Pamela Youde Nethersole Eastern Hospital, Hong Kong. Patients All patients with medically inoperable stage I non-small-cell lung carcinoma receiving stereotactic ablative radiotherapy since its establishment in 2008. Main outcome measures Disease control rate, overall survival, and treatment toxicities. Results Sixteen stage I non-small-cell lung carcinoma patients underwent the procedure from June 2008 to November 2011. The median patient age was 82 years and the majority (81%) had moderate-tosevere co-morbidity based on the Adult Comorbidity Evaluation 27 index. With a median follow-up of 22 months, the 2-year primary tumour control rate, disease-free survival and overall survival rates were 91%, 71% and 87%, respectively. No grade 3 (National Cancer Institute Common Terminology Criteria for Adverse Events) or higher treatment-related complications were reported. Conclusion Stereotactic ablative radiotherapy can achieve a high degree of local control safely in medically inoperable patients with early lung cancer.-
dc.languageeng-
dc.relation.ispartofHong Kong Medical Journal-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectLung neoplasms-
dc.subjectNon-small-cell lung-
dc.subjectRadiotherapy-
dc.subjectStereotaxic techniques-
dc.subjectSurvival rate-
dc.subjectCarcinoma-
dc.titleStereotactic ablative radiotherapy for medically inoperable early stage lung cancer: early outcomes-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.pmid23018069-
dc.identifier.scopuseid_2-s2.0-84870952632-
dc.identifier.hkuros266673-
dc.identifier.volume18-
dc.identifier.issue5-
dc.identifier.spage412-
dc.identifier.epage418-

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