File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Analysis of cervical cancer in chinese patients treated with chemoradiation or radiotherapy alone

TitleAnalysis of cervical cancer in chinese patients treated with chemoradiation or radiotherapy alone
Authors
KeywordsAsian continental ancestry group
Drug therapy
Radiotherapy
Toxicity
Carcinoma, squamous cell
Issue Date2007
Citation
Journal of the Hong Kong College of Radiologists, 2007, v. 10, n. 2, p. 51-58 How to Cite?
AbstractAim: A retrospective review was performed to compare chemoradiation and radiotherapy alone for the treatment of carcinoma of the cervix in a Hong Kong Chinese population. Patients and Methods: 208 Chinese patients with carcinoma of the cervix stage I to IVA were treated with radical intent between 1994 and 2004. 177 patients (85.1%) received radiotherapy alone and 31 patients (14.9%) received chemoradiation. Radiotherapy consisted of external beam pelvic irradiation followed by low-dose rate brachytherapy and additional parametrial irradiation. Patients in the chemoradiation group received weekly cisplatin during external irradiation. Results: The median age was 65.4 years (range, 32.6 to 90.2 years). The median follow-up time was 5.0 years (range, 0.2 to 12.1 years) for patients in the radiotherapy group and 3.4 years (range, 0.5 to 6.6 years) for patients in the chemoradiation group. At 3 years, the overall survival was 74.7% for the radiotherapy group and 87.5% for the chemoradiation group (p = 0.23). The 3-year disease-free survival was 71.5% for the radiotherapy group and 77.4% for the chemoradiation group (p = 0.23). The overall 3-year actuarial late toxicity was 26.4% (4.3% grade 3 to 4) in the radiotherapy group and 15.2% (0% grade 3 to 4) in the chemoradiation group. Conclusions: Due to the limited number of patients in the chemoradiation group, the survival benefit for chemoradiation for cervical cancer could not be demonstrated. Nevertheless, the treatment was well tolerated by Chinese patients and there was no increase in late toxicities. © 2007 Hong Kong College of Radiologists.
Persistent Identifierhttp://hdl.handle.net/10722/213913
ISSN

 

DC FieldValueLanguage
dc.contributor.authorChoi, C. Y.-
dc.contributor.authorNg, W. T.-
dc.contributor.authorChang, A. T Y-
dc.contributor.authorSoong, I. S.-
dc.contributor.authorLee, A. W M-
dc.date.accessioned2015-08-19T13:41:12Z-
dc.date.available2015-08-19T13:41:12Z-
dc.date.issued2007-
dc.identifier.citationJournal of the Hong Kong College of Radiologists, 2007, v. 10, n. 2, p. 51-58-
dc.identifier.issn1029-5097-
dc.identifier.urihttp://hdl.handle.net/10722/213913-
dc.description.abstractAim: A retrospective review was performed to compare chemoradiation and radiotherapy alone for the treatment of carcinoma of the cervix in a Hong Kong Chinese population. Patients and Methods: 208 Chinese patients with carcinoma of the cervix stage I to IVA were treated with radical intent between 1994 and 2004. 177 patients (85.1%) received radiotherapy alone and 31 patients (14.9%) received chemoradiation. Radiotherapy consisted of external beam pelvic irradiation followed by low-dose rate brachytherapy and additional parametrial irradiation. Patients in the chemoradiation group received weekly cisplatin during external irradiation. Results: The median age was 65.4 years (range, 32.6 to 90.2 years). The median follow-up time was 5.0 years (range, 0.2 to 12.1 years) for patients in the radiotherapy group and 3.4 years (range, 0.5 to 6.6 years) for patients in the chemoradiation group. At 3 years, the overall survival was 74.7% for the radiotherapy group and 87.5% for the chemoradiation group (p = 0.23). The 3-year disease-free survival was 71.5% for the radiotherapy group and 77.4% for the chemoradiation group (p = 0.23). The overall 3-year actuarial late toxicity was 26.4% (4.3% grade 3 to 4) in the radiotherapy group and 15.2% (0% grade 3 to 4) in the chemoradiation group. Conclusions: Due to the limited number of patients in the chemoradiation group, the survival benefit for chemoradiation for cervical cancer could not be demonstrated. Nevertheless, the treatment was well tolerated by Chinese patients and there was no increase in late toxicities. © 2007 Hong Kong College of Radiologists.-
dc.languageeng-
dc.relation.ispartofJournal of the Hong Kong College of Radiologists-
dc.subjectAsian continental ancestry group-
dc.subjectDrug therapy-
dc.subjectRadiotherapy-
dc.subjectToxicity-
dc.subjectCarcinoma, squamous cell-
dc.titleAnalysis of cervical cancer in chinese patients treated with chemoradiation or radiotherapy alone-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-42649134857-
dc.identifier.volume10-
dc.identifier.issue2-
dc.identifier.spage51-
dc.identifier.epage58-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats