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Article: Cellular-level surgery using nano robots

TitleCellular-level surgery using nano robots
Authors
KeywordsAFM
Cellular-level surgery
Nano robot
Multifunctions
Issue Date2012
Citation
Journal of Laboratory Automation, 2012, v. 17, n. 6, p. 425-434 How to Cite?
AbstractThe atomic force microscope (AFM) is a popular instrument for studying the nano world. AFM is naturally suitable for imaging living samples and measuring mechanical properties. In this article, we propose a new concept of an AFM-based nano robot that can be applied for cellular-level surgery on living samples. The nano robot has multiple functions of imaging, manipulation, characterizing mechanical properties, and tracking. In addition, the technique of tip functionalization allows the nano robot the ability for precisely delivering a drug locally. Therefore, the nano robot can be used for conducting complicated nano surgery on living samples, such as cells and bacteria. Moreover, to provide a user-friendly interface, the software in this nano robot provides a "videolized" visual feedback for monitoring the dynamic changes on the sample surface. Both the operation of nano surgery and observation of the surgery results can be simultaneously achieved. This nano robot can be easily integrated with extra modules that have the potential applications of characterizing other properties of samples such as local conductance and capacitance. © 2012 Society for Laboratory Automation and Screening.
Persistent Identifierhttp://hdl.handle.net/10722/213299
ISSN
2015 Impact Factor: 1.297
2015 SCImago Journal Rankings: 0.422

 

DC FieldValueLanguage
dc.contributor.authorSong, Bo-
dc.contributor.authorYang, Ruiguo-
dc.contributor.authorXi, Ning-
dc.contributor.authorPatterson, Kevin Charles-
dc.contributor.authorQu, Chengeng-
dc.contributor.authorLai, King Wai Chiu-
dc.date.accessioned2015-07-28T04:06:49Z-
dc.date.available2015-07-28T04:06:49Z-
dc.date.issued2012-
dc.identifier.citationJournal of Laboratory Automation, 2012, v. 17, n. 6, p. 425-434-
dc.identifier.issn2211-0682-
dc.identifier.urihttp://hdl.handle.net/10722/213299-
dc.description.abstractThe atomic force microscope (AFM) is a popular instrument for studying the nano world. AFM is naturally suitable for imaging living samples and measuring mechanical properties. In this article, we propose a new concept of an AFM-based nano robot that can be applied for cellular-level surgery on living samples. The nano robot has multiple functions of imaging, manipulation, characterizing mechanical properties, and tracking. In addition, the technique of tip functionalization allows the nano robot the ability for precisely delivering a drug locally. Therefore, the nano robot can be used for conducting complicated nano surgery on living samples, such as cells and bacteria. Moreover, to provide a user-friendly interface, the software in this nano robot provides a "videolized" visual feedback for monitoring the dynamic changes on the sample surface. Both the operation of nano surgery and observation of the surgery results can be simultaneously achieved. This nano robot can be easily integrated with extra modules that have the potential applications of characterizing other properties of samples such as local conductance and capacitance. © 2012 Society for Laboratory Automation and Screening.-
dc.languageeng-
dc.relation.ispartofJournal of Laboratory Automation-
dc.subjectAFM-
dc.subjectCellular-level surgery-
dc.subjectNano robot-
dc.subjectMultifunctions-
dc.titleCellular-level surgery using nano robots-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1177/2211068212460665-
dc.identifier.pmid23015517-
dc.identifier.scopuseid_2-s2.0-84875692791-
dc.identifier.volume17-
dc.identifier.issue6-
dc.identifier.spage425-
dc.identifier.epage434-
dc.identifier.eissn2211-0690-

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