File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Model-Based Iterative Reconstruction in Low-Dose CT Colonography-Feasibility Study in 65 Patients for Symptomatic Investigation

TitleModel-Based Iterative Reconstruction in Low-Dose CT Colonography-Feasibility Study in 65 Patients for Symptomatic Investigation
Authors
Issue Date2015
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/arad
Citation
Academic Radiology, 2015, v. 22 n. 5, p. 563-571 How to Cite?
AbstractRATIONALE AND OBJECTIVES: To compare image quality on computed tomographic colonography (CTC) acquired at standard dose (STD) and low dose (LD) using filtered-back projection, adaptive statistical iterative reconstruction, and model-based iterative reconstruction (MBIR) techniques. MATERIALS AND METHODS: A total of 65 symptomatic patients were prospectively enrolled for the study and underwent STD and LD CTC with filtered-back projection, adaptive statistical iterative reconstruction, and MBIR to allow direct per-patient comparison. Objective image noise, subjective image analyses, and polyp detection were assessed. RESULTS: Objective image noise analysis demonstrates significant noise reduction using MBIR technique (P < .05) despite being acquired at lower doses. Subjective image analyses were superior for LD MBIR in all parameters except visibility of extracolonic lesions (two-dimensional) and visibility of colonic wall (three-dimensional) where there were no significant differences. There was no significant difference in polyp detection rates (P > .05). Doses: LD (dose-length product, 257.7), STD (dose-length product, 483.6). CONCLUSIONS: LD MBIR CTC objectively shows improved image noise using parameters in our study. Subjectively, image quality is maintained. Polyp detection shows no significant difference but because of small numbers needs further validation. Average dose reduction of 47% can be achieved. This study confirms feasibility of using MBIR in this context of CTC in symptomatic population.
Persistent Identifierhttp://hdl.handle.net/10722/210719
ISSN
2015 Impact Factor: 1.966
2015 SCImago Journal Rankings: 1.008

 

DC FieldValueLanguage
dc.contributor.authorVardhanabhuti, V-
dc.contributor.authorJames, J-
dc.contributor.authorNensey, R-
dc.contributor.authorHyde, C-
dc.contributor.authorRoobottom, C-
dc.date.accessioned2015-06-23T05:48:21Z-
dc.date.available2015-06-23T05:48:21Z-
dc.date.issued2015-
dc.identifier.citationAcademic Radiology, 2015, v. 22 n. 5, p. 563-571-
dc.identifier.issn1076-6332-
dc.identifier.urihttp://hdl.handle.net/10722/210719-
dc.description.abstractRATIONALE AND OBJECTIVES: To compare image quality on computed tomographic colonography (CTC) acquired at standard dose (STD) and low dose (LD) using filtered-back projection, adaptive statistical iterative reconstruction, and model-based iterative reconstruction (MBIR) techniques. MATERIALS AND METHODS: A total of 65 symptomatic patients were prospectively enrolled for the study and underwent STD and LD CTC with filtered-back projection, adaptive statistical iterative reconstruction, and MBIR to allow direct per-patient comparison. Objective image noise, subjective image analyses, and polyp detection were assessed. RESULTS: Objective image noise analysis demonstrates significant noise reduction using MBIR technique (P < .05) despite being acquired at lower doses. Subjective image analyses were superior for LD MBIR in all parameters except visibility of extracolonic lesions (two-dimensional) and visibility of colonic wall (three-dimensional) where there were no significant differences. There was no significant difference in polyp detection rates (P > .05). Doses: LD (dose-length product, 257.7), STD (dose-length product, 483.6). CONCLUSIONS: LD MBIR CTC objectively shows improved image noise using parameters in our study. Subjectively, image quality is maintained. Polyp detection shows no significant difference but because of small numbers needs further validation. Average dose reduction of 47% can be achieved. This study confirms feasibility of using MBIR in this context of CTC in symptomatic population.-
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/arad-
dc.relation.ispartofAcademic Radiology-
dc.titleModel-Based Iterative Reconstruction in Low-Dose CT Colonography-Feasibility Study in 65 Patients for Symptomatic Investigation-
dc.typeArticle-
dc.identifier.emailVardhanabhuti, V: varv@hku.hk-
dc.identifier.authorityVardhanabhuti, V=rp01900-
dc.identifier.doi10.1016/j.acra.2014.12.017-
dc.identifier.pmid25683499-
dc.identifier.hkuros243525-
dc.identifier.volume22-
dc.identifier.issue5-
dc.identifier.spage563-
dc.identifier.epage571-
dc.publisher.placeNetherlands-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats