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  Patent History
  • Application
    US 08/865597 1997-05-29
  • Granted
    US 5973131 1999-10-26
Supplementary

granted patent: Penicillium marneffei antigenic Protein 1

TitlePenicillium marneffei antigenic Protein 1
Granted PatentUS 5973131
Granted Date1999-10-26
Priority Date1996-05-30 US 08/655730
1997-05-29 US 08/865597
Inventors
Issue Date1999
Citation
US Patent US 5973131. Washington, DC: US Patent and Trademark Office (USPTO), 1999 How to Cite?
AbstractDisclosed is a Penicillium marneffei PMAP1 polypeptide and DNA(RNA) encoding such PMAP1 polypeptide. Also provided is a procedure for producing such polypeptide by recombinant DNA techniques and a procedure for generating antibodies against the said polypeptide. Also disclosed is a method of using such polypeptide and the antibodies against it for the diagnosis of systemic infections of Penicillium marneffei by detecting the presence of the specific antibodies as well as the PMAP1 protein antigen in clinical specimens taken from suspected patients. Also provided are methods of using the PMAP1 DNA(RNA) or protein sequence to identify and to clone its homologous genes from other pathogenic fungi. Therefore, the identification of PMAP1 homologous genes from other pathogenic fungi are made possible with this invention. Also described is a therapeutic regimen using the antibodies against Penicillium infection. Also provided is a method of immunization against the infection of Penicillium.
Persistent Identifierhttp://hdl.handle.net/10722/210545

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:04:18Z-
dc.date.available2015-06-17T07:04:18Z-
dc.date.issued1999-
dc.identifier.citationUS Patent US 5973131. Washington, DC: US Patent and Trademark Office (USPTO), 1999-
dc.identifier.urihttp://hdl.handle.net/10722/210545-
dc.description.abstractDisclosed is a Penicillium marneffei PMAP1 polypeptide and DNA(RNA) encoding such PMAP1 polypeptide. Also provided is a procedure for producing such polypeptide by recombinant DNA techniques and a procedure for generating antibodies against the said polypeptide. Also disclosed is a method of using such polypeptide and the antibodies against it for the diagnosis of systemic infections of Penicillium marneffei by detecting the presence of the specific antibodies as well as the PMAP1 protein antigen in clinical specimens taken from suspected patients. Also provided are methods of using the PMAP1 DNA(RNA) or protein sequence to identify and to clone its homologous genes from other pathogenic fungi. Therefore, the identification of PMAP1 homologous genes from other pathogenic fungi are made possible with this invention. Also described is a therapeutic regimen using the antibodies against Penicillium infection. Also provided is a method of immunization against the infection of Penicillium.-
dc.relation.isreferencedbyEP 1576103 (A2) 2005-09-21 -
dc.relation.isreferencedby E P1576103 (B1) 2010-12-01-
dc.relation.isreferencedbyUS 2003215950 (A1) 2003-11-20 -
dc.relation.isreferencedby U S7439067 (B2) 2008-10-21-
dc.relation.isreferencedby E P1576103 (A4) 2007-03-14 -
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titlePenicillium marneffei antigenic Protein 1-
dc.typePatent-
dc.identifier.authorityYUEN, KWOK YUNG=rp00366-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorCAO, LIANG-
dc.contributor.inventorYUEN, KWOK YUNG-
patents.identifier.applicationUS 08/865597-
patents.identifier.grantedUS 5973131-
patents.description.assigneeCAO, LIANG, ; YUEN, KWOK YUNG-
patents.description.countryUnited States of America -
patents.date.granted1999-10-26-
patents.identifier.hkutechidMicro-1996-00085-1-
patents.date.application1997-05-29-
patents.date.priority1996-05-30 US 08/655730-
patents.date.priority1997-05-29 US 08/865597-
patents.description.ccus-
patents.description.kindA-
patents.typePatent_granted-

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