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Conference Paper: Treating normal tension glaucoma with selective laser trabeculoplasty

TitleTreating normal tension glaucoma with selective laser trabeculoplasty
Authors
Issue Date2013
PublisherThe College of Ophthalmologists of Hong Kong and the Hong Kong Ophthalmological Society.
Citation
The 25th Annual Scientific Meeting - Hong Kong Ophthalmological Symposium 2013 (ASM 2013), Hong Kong, China, 14-15 December 2013. How to Cite?
AbstractPURPOSE: The purpose of this study was to investigate the efficacy of selective laser trabeculoplasty (SLT) in the treatment of normal tension glaucoma (NTG). METHODS: This prospective cohort study recruited consecutive cases of NTG on antiglaucoma medication. Cases were excluded for previous glaucoma surgery or laser. All patients underwent a 1-month washout of medication followed by a mean baseline intraocular pressure (IOP) measured at 9 AM, 1 PM, and 5 PM. A 30% reduction from baseline was set as the target IOP. A single session of SLT was performed to 360 degrees of the trabecular meshwork. IOP phasing was repeated at 1 month after SLT and medication was resumed to achieve the target IOP. Patients were followed up to 6 months after SLT. RESULTS: In 83 eyes of 46 subjects, the mean prestudy IOP was 14.2 ± 3.1 mm Hg when on 1.5 ± 0.9 antiglaucoma medication. The mean baseline IOP without medication was 16.1 ± 2.2 mm Hg. The mean SLT shots applied was 187.8 ± 27.5 using a mean energy of 1.0 ± 0.07 mJ. At 1-month post-SLT, the IOP was 12.7 ± 2.0 mm Hg (21.6% IOP reduction) from baseline without medication (P<0.05). The 6-month IOP was 11.4 ± 1.6 mm Hg when on 1.1± 1.0 medications, representing a 19.7% reduction from prestudy IOP, a 29.6% reduction from baseline IOP, and a 26.7% reduction in antiglaucoma medication (all P< 0.05). A higher baseline IOP was correlated with greater IOP reduction with SLT (r=0.3, P=0.009). CONCLUSIONS: A single session of SLT for NTG achieved an additional 20% reduction in IOP with 27% less medication at 6 months compared with prestudy levels while maintaining a 30% reduction from baseline IOP.
DescriptionConference Theme: Cataract and Refractive Surgery
Persistent Identifierhttp://hdl.handle.net/10722/208667

 

DC FieldValueLanguage
dc.contributor.authorLee, WYJ-
dc.contributor.authorGangwani, RA-
dc.contributor.authorChan, JC-
dc.contributor.authorLai, JSM-
dc.date.accessioned2015-03-18T07:26:49Z-
dc.date.available2015-03-18T07:26:49Z-
dc.date.issued2013-
dc.identifier.citationThe 25th Annual Scientific Meeting - Hong Kong Ophthalmological Symposium 2013 (ASM 2013), Hong Kong, China, 14-15 December 2013.-
dc.identifier.urihttp://hdl.handle.net/10722/208667-
dc.descriptionConference Theme: Cataract and Refractive Surgery-
dc.description.abstractPURPOSE: The purpose of this study was to investigate the efficacy of selective laser trabeculoplasty (SLT) in the treatment of normal tension glaucoma (NTG). METHODS: This prospective cohort study recruited consecutive cases of NTG on antiglaucoma medication. Cases were excluded for previous glaucoma surgery or laser. All patients underwent a 1-month washout of medication followed by a mean baseline intraocular pressure (IOP) measured at 9 AM, 1 PM, and 5 PM. A 30% reduction from baseline was set as the target IOP. A single session of SLT was performed to 360 degrees of the trabecular meshwork. IOP phasing was repeated at 1 month after SLT and medication was resumed to achieve the target IOP. Patients were followed up to 6 months after SLT. RESULTS: In 83 eyes of 46 subjects, the mean prestudy IOP was 14.2 ± 3.1 mm Hg when on 1.5 ± 0.9 antiglaucoma medication. The mean baseline IOP without medication was 16.1 ± 2.2 mm Hg. The mean SLT shots applied was 187.8 ± 27.5 using a mean energy of 1.0 ± 0.07 mJ. At 1-month post-SLT, the IOP was 12.7 ± 2.0 mm Hg (21.6% IOP reduction) from baseline without medication (P<0.05). The 6-month IOP was 11.4 ± 1.6 mm Hg when on 1.1± 1.0 medications, representing a 19.7% reduction from prestudy IOP, a 29.6% reduction from baseline IOP, and a 26.7% reduction in antiglaucoma medication (all P< 0.05). A higher baseline IOP was correlated with greater IOP reduction with SLT (r=0.3, P=0.009). CONCLUSIONS: A single session of SLT for NTG achieved an additional 20% reduction in IOP with 27% less medication at 6 months compared with prestudy levels while maintaining a 30% reduction from baseline IOP.-
dc.languageeng-
dc.publisherThe College of Ophthalmologists of Hong Kong and the Hong Kong Ophthalmological Society.-
dc.relation.ispartofAnnual Scientific Meeting - Hong Kong Ophthalmological Symposium, ASM 2013-
dc.titleTreating normal tension glaucoma with selective laser trabeculoplasty-
dc.typeConference_Paper-
dc.identifier.emailLee, WYJ: jackylee@hku.hk-
dc.identifier.emailGangwani, RA: gangwani@hku.hk-
dc.identifier.emailLai, JSM: laism@hku.hk-
dc.publisher.placeHong Kong-

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