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Article: Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma

TitleContinuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
Authors
Issue Date2015
Citation
Clinical Ophthalmology, 2015, v. 9, p. 197-202 How to Cite?
AbstractPURPOSE: To analyze the 24-hour ocular dimensional profile in normal-tension glaucoma (NTG) patients on medical treatment. METHODS: Consecutive, medically treated NTG subjects were recruited from a university eye center. Subjects were on a mean of 1.7+/-0.7 types of antiglaucoma medications and 56.6% were on a prostaglandin analog. A contact lens-based sensor device was worn in one eye of NTG patients to record the intraocular pressure (IOP)-related profile for 24 hours, recording the following: variability from mean over 24 hours, nocturnally and diurnally, as well as the number of peaks and troughs diurnally and nocturnally. RESULTS: In 18 NTG subjects, the nocturnal variability around the mean contact lens-based sensor device signal was 48.9% less than the diurnal variability around the mean. The number of peaks was 54.7% less during the nocturnal period than during the diurnal period. The rate of increase in the ocular dimensional profile when going to sleep was significantly greater than the rate of decrease upon waking (P<0.001). CONCLUSION: In medically treated NTG subjects, there was more variability in the IOP-related pattern during the daytime and there were fewer peaks during sleep.
Persistent Identifierhttp://hdl.handle.net/10722/208507
ISSN
2015 SCImago Journal Rankings: 0.787
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorLee, WYJen_US
dc.contributor.authorFu, Len_US
dc.contributor.authorShum, JWen_US
dc.contributor.authorChan, JCHen_US
dc.contributor.authorLai, JSen_US
dc.date.accessioned2015-03-11T07:06:30Z-
dc.date.available2015-03-11T07:06:30Z-
dc.date.issued2015en_US
dc.identifier.citationClinical Ophthalmology, 2015, v. 9, p. 197-202en_US
dc.identifier.issn1177-5467en_US
dc.identifier.urihttp://hdl.handle.net/10722/208507-
dc.description.abstractPURPOSE: To analyze the 24-hour ocular dimensional profile in normal-tension glaucoma (NTG) patients on medical treatment. METHODS: Consecutive, medically treated NTG subjects were recruited from a university eye center. Subjects were on a mean of 1.7+/-0.7 types of antiglaucoma medications and 56.6% were on a prostaglandin analog. A contact lens-based sensor device was worn in one eye of NTG patients to record the intraocular pressure (IOP)-related profile for 24 hours, recording the following: variability from mean over 24 hours, nocturnally and diurnally, as well as the number of peaks and troughs diurnally and nocturnally. RESULTS: In 18 NTG subjects, the nocturnal variability around the mean contact lens-based sensor device signal was 48.9% less than the diurnal variability around the mean. The number of peaks was 54.7% less during the nocturnal period than during the diurnal period. The rate of increase in the ocular dimensional profile when going to sleep was significantly greater than the rate of decrease upon waking (P<0.001). CONCLUSION: In medically treated NTG subjects, there was more variability in the IOP-related pattern during the daytime and there were fewer peaks during sleep.en_US
dc.languageengen_US
dc.relation.ispartofClinical Ophthalmologyen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleContinuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucomaen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.2147/OPTH.S75344en_US
dc.identifier.pmid25678768-
dc.identifier.pmcid4322878-
dc.identifier.pmcidPMC4322878-
dc.identifier.volume9en_US
dc.identifier.spage197en_US
dc.identifier.epage202en_US

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