File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The value of the 24-h delayed abdominal radiograph of barium enema in the diagnosis of Hirschsprung's disease

TitleThe value of the 24-h delayed abdominal radiograph of barium enema in the diagnosis of Hirschsprung's disease
Authors
KeywordsDelayed film
Diagnosis
Hirschsprung’s disease
Rectal biopsy
Contrast enema
Issue Date2015
Citation
Pediatric Surgery International, 2015, v. 31 n. 1, p. 11-15 How to Cite?
AbstractAim of study The objective of this study is to determine the diagnostic value of the 24-h delayed film for Hirschsprung’s disease (HD). Other features of the barium enema were also examined, in particular the correlation between the radiological transition zone (TZ) and the final pathology. Methods All patients with suspected HD from 2003 to 2013 who had undergone barium enema and rectal biopsy were reviewed retrospectively to study the correlation between radiological features of barium enema with the final diagnosis as well as severity. Results A total of 182 patients were admitted for suspected HD during the study period, of which 82 had both investigations done. 68 patients had radiological features suggestive of the disease and ultimately, 12 patients had the disease confirmed with rectal biopsy. Among those without radiological features of HD, 2 patients were found to have the disease. Thus, the sensitivity of the 24-h delayed film was 85.7 % and the specificity was 17.6 %. The positive predictive value (PPV) of this test was 20.6 % and the negative predictive value (NPV) was 85.7 %. Regarding the level of TZ, it was not detected in the barium enema in 7 (50 %) out of the 14 patients. For those with the presence of TZ, 6 (85.7 %) of them correlated well with the intra-operative findings and 4 (57.1 %) of them correlated well with the final histology. Conclusion The 24-h delayed film of barium enema has a high NPV and is useful to rule out HD. However, rectal biopsy is still suggested for disease confirmation given its low PPV. Lastly, once present, the level of radiological TZ is also a useful predictor for the actual disease involvement. © Springer-Verlag Berlin Heidelberg 2014.
Persistent Identifierhttp://hdl.handle.net/10722/208288
ISSN
2015 Impact Factor: 1.01
2015 SCImago Journal Rankings: 0.409
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, CWYen_US
dc.contributor.authorLau, CTen_US
dc.contributor.authorChung, HYen_US
dc.contributor.authorLam, WMWen_US
dc.contributor.authorWong, KKYen_US
dc.contributor.authorTam, PKHen_US
dc.date.accessioned2015-02-23T08:18:38Z-
dc.date.available2015-02-23T08:18:38Z-
dc.date.issued2015en_US
dc.identifier.citationPediatric Surgery International, 2015, v. 31 n. 1, p. 11-15en_US
dc.identifier.issn0179-0358-
dc.identifier.urihttp://hdl.handle.net/10722/208288-
dc.description.abstractAim of study The objective of this study is to determine the diagnostic value of the 24-h delayed film for Hirschsprung’s disease (HD). Other features of the barium enema were also examined, in particular the correlation between the radiological transition zone (TZ) and the final pathology. Methods All patients with suspected HD from 2003 to 2013 who had undergone barium enema and rectal biopsy were reviewed retrospectively to study the correlation between radiological features of barium enema with the final diagnosis as well as severity. Results A total of 182 patients were admitted for suspected HD during the study period, of which 82 had both investigations done. 68 patients had radiological features suggestive of the disease and ultimately, 12 patients had the disease confirmed with rectal biopsy. Among those without radiological features of HD, 2 patients were found to have the disease. Thus, the sensitivity of the 24-h delayed film was 85.7 % and the specificity was 17.6 %. The positive predictive value (PPV) of this test was 20.6 % and the negative predictive value (NPV) was 85.7 %. Regarding the level of TZ, it was not detected in the barium enema in 7 (50 %) out of the 14 patients. For those with the presence of TZ, 6 (85.7 %) of them correlated well with the intra-operative findings and 4 (57.1 %) of them correlated well with the final histology. Conclusion The 24-h delayed film of barium enema has a high NPV and is useful to rule out HD. However, rectal biopsy is still suggested for disease confirmation given its low PPV. Lastly, once present, the level of radiological TZ is also a useful predictor for the actual disease involvement. © Springer-Verlag Berlin Heidelberg 2014.-
dc.languageengen_US
dc.relation.ispartofPediatric Surgery Internationalen_US
dc.subjectDelayed film-
dc.subjectDiagnosis-
dc.subjectHirschsprung’s disease-
dc.subjectRectal biopsy-
dc.subjectContrast enema-
dc.titleThe value of the 24-h delayed abdominal radiograph of barium enema in the diagnosis of Hirschsprung's diseaseen_US
dc.typeArticleen_US
dc.identifier.emailChung, HY: chungphy@hku.hken_US
dc.identifier.emailWong, KKY: kkywong@hku.hken_US
dc.identifier.emailTam, PKH: paultam@hku.hken_US
dc.identifier.authorityChung, HY=rp02002en_US
dc.identifier.authorityWong, KKY=rp01392en_US
dc.identifier.authorityTam, PKH=rp00060en_US
dc.identifier.doi10.1007/s00383-014-3632-5-
dc.identifier.pmid25348880-
dc.identifier.scopuseid_2-s2.0-84926665897-
dc.identifier.hkuros242445en_US
dc.identifier.volume31en_US
dc.identifier.issue1en_US
dc.identifier.spage11en_US
dc.identifier.epage15en_US
dc.identifier.isiWOS:000347291400002-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats