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Article: Worsened arterial stiffness in high-risk cardiovascular patients with high habitual carbohydrate intake: a cross-sectional vascular function study
Title | Worsened arterial stiffness in high-risk cardiovascular patients with high habitual carbohydrate intake: a cross-sectional vascular function study |
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Authors | |
Keywords | Aged Cardiovascular Diseases/diagnosis/*etiology/physiopathology Case-Control Studies China Cross-Sectional Studies Dietary Carbohydrates/*adverse effects Energy Intake Female *Food Habits Humans Male Middle Aged Nutritional Status Pulse Wave Analysis Questionnaires Risk Factors *Vascular Stiffness |
Issue Date | 2014 |
Citation | BMC Cardiovasc Disord, 2014, v. 14, p. 24-24 How to Cite? |
Abstract | BACKGROUND: Previous studies suggested that high dietary carbohydrate intake is associated with increased cardiovascular risk through raised triglyceride and decreased high-density lipoprotein-cholesterol levels. However, the relation between carbohydrate intake and arterial stiffness has not been established. The purpose of this study was to examine this relation among high-risk cardiovascular patients. METHODS: We studied the relation between dietary macronutrient intake and arterial stiffness in 364 patients with documented cardiovascular diseases or risk equivalent (coronary artery diseases 62%, ischemic stroke 13%, diabetes mellitus 55%) and in 93 age-and-sex matched control subjects. Dietary macronutrient intake was assessed using a validated food-frequency questionnaire (FFQ) for Chinese. Heart-ankle pulse wave velocity (PWV) was measured non-invasively with a Vascular Profiling System (VP2000, Colin Corp. USA). A dietary pattern with >/=60% total energy intake derived from carbohydrates was defined as a high-carbohydrate diet according to the Dietary Reference Intakes (DRI) for Chinese. RESULTS: Subjects who consumed a high-carbohydrate diet had significantly higher mean PWV than those who did not consume a high-carbohydrate diet (P = 0.039). After adjustment for potential confounders, high-carbohydrate diet was associated with significantly increased PWV [B = 73.50 (10.81 to 136.19), P = 0.022]. However, there was no significant association between high-carbohydrate diet and PWV in controls (P = 0.634). CONCLUSIONS: High-carbohydrate diet is associated with increased arterial stiffness in patients with established cardiovascular disease or risk equivalent. |
Persistent Identifier | http://hdl.handle.net/10722/207689 |
ISSN | 2023 Impact Factor: 2.0 2023 SCImago Journal Rankings: 0.646 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, HT | en_US |
dc.contributor.author | Chan, YH | en_US |
dc.contributor.author | Yiu, KH | en_US |
dc.contributor.author | Li, SW | en_US |
dc.contributor.author | Tam, S | en_US |
dc.contributor.author | Lau, CP | en_US |
dc.contributor.author | Tse, HF | en_US |
dc.date.accessioned | 2015-01-19T04:20:03Z | - |
dc.date.available | 2015-01-19T04:20:03Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | BMC Cardiovasc Disord, 2014, v. 14, p. 24-24 | en_US |
dc.identifier.issn | 1471-2261 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/207689 | - |
dc.description.abstract | BACKGROUND: Previous studies suggested that high dietary carbohydrate intake is associated with increased cardiovascular risk through raised triglyceride and decreased high-density lipoprotein-cholesterol levels. However, the relation between carbohydrate intake and arterial stiffness has not been established. The purpose of this study was to examine this relation among high-risk cardiovascular patients. METHODS: We studied the relation between dietary macronutrient intake and arterial stiffness in 364 patients with documented cardiovascular diseases or risk equivalent (coronary artery diseases 62%, ischemic stroke 13%, diabetes mellitus 55%) and in 93 age-and-sex matched control subjects. Dietary macronutrient intake was assessed using a validated food-frequency questionnaire (FFQ) for Chinese. Heart-ankle pulse wave velocity (PWV) was measured non-invasively with a Vascular Profiling System (VP2000, Colin Corp. USA). A dietary pattern with >/=60% total energy intake derived from carbohydrates was defined as a high-carbohydrate diet according to the Dietary Reference Intakes (DRI) for Chinese. RESULTS: Subjects who consumed a high-carbohydrate diet had significantly higher mean PWV than those who did not consume a high-carbohydrate diet (P = 0.039). After adjustment for potential confounders, high-carbohydrate diet was associated with significantly increased PWV [B = 73.50 (10.81 to 136.19), P = 0.022]. However, there was no significant association between high-carbohydrate diet and PWV in controls (P = 0.634). CONCLUSIONS: High-carbohydrate diet is associated with increased arterial stiffness in patients with established cardiovascular disease or risk equivalent. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | BMC Cardiovasc Disord | en_US |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Aged | en_US |
dc.subject | Cardiovascular Diseases/diagnosis/*etiology/physiopathology | en_US |
dc.subject | Case-Control Studies | en_US |
dc.subject | China | en_US |
dc.subject | Cross-Sectional Studies | en_US |
dc.subject | Dietary Carbohydrates/*adverse effects | en_US |
dc.subject | Energy Intake | en_US |
dc.subject | Female | en_US |
dc.subject | *Food Habits | en_US |
dc.subject | Humans | en_US |
dc.subject | Male | en_US |
dc.subject | Middle Aged | en_US |
dc.subject | Nutritional Status | en_US |
dc.subject | Pulse Wave Analysis | en_US |
dc.subject | Questionnaires | en_US |
dc.subject | Risk Factors | en_US |
dc.subject | *Vascular Stiffness | en_US |
dc.title | Worsened arterial stiffness in high-risk cardiovascular patients with high habitual carbohydrate intake: a cross-sectional vascular function study | en_US |
dc.type | Article | en_US |
dc.identifier.email | Yiu, KH: khkyiu@hku.hk | en_US |
dc.identifier.authority | Yiu, KH=rp01490 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/1471-2261-14-24 | en_US |
dc.identifier.scopus | eid_2-s2.0-84896716280 | - |
dc.identifier.hkuros | 253825 | - |
dc.identifier.volume | 14 | en_US |
dc.identifier.spage | 24 | en_US |
dc.identifier.epage | 24 | en_US |
dc.identifier.isi | WOS:000334535300001 | - |
dc.identifier.issnl | 1471-2261 | - |