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postgraduate thesis: Intake of trans fatty acid and risk of cardiovascular disease in Asian population : a systematic review

TitleIntake of trans fatty acid and risk of cardiovascular disease in Asian population : a systematic review
Authors
Issue Date2014
PublisherThe University of Hong Kong (Pokfulam, Hong Kong)
Citation
Wang, Z. [王浙潤.王浙润]. (2014). Intake of trans fatty acid and risk of cardiovascular disease in Asian population : a systematic review. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5320726
AbstractBackground Many studies in western countries have suggested a positive association between intake of trans fatty acid (TFA) and risk of cardiovascular diseases (CVDs). In Asia, although intake of TFA was relatively low, it evidenced an increasing trend which was accompanied with an increasing prevalence of CVDs among the population. There was currently no systematic review on the relationship between intake of TFA and CVDs in Asian population. This systematic review was aimed to synthesize the association between intake of TFA and the risk of CVDs in Asian population from published literature. Methods Both English and Chinese literature published before 1st January 2014were retrieved from PubMed, Medline, Google scholaand CNKI with a combination of keywords. Studies that reported the associations between intake of TFA and CVD-related risks and those conducted among Asian population were included. The quality of eligible literature included in the review was assessed based on STROBE. Findings regarding the associations between intake of TFA and risk of CVDs were extracted and synthesized through comparing and evaluating the quality of findings across the included studies. Results Of the 378 articles retrieved from the datasets, nine studies were eligible to be included in this systematic review. The nine studies covered six Asian countries including Iran, China, Korea, Japan, Israel and India. Seven of nine studies indicated a positive association between intake of TFA and risk of CVDs while the other two reported no significant association. However, none of the included studies were interventional studies and only one was prospective cohort study. Conclusion The findings that more intake of TFA was associated with increased risk of CVDs in Asian population were consistent with that in the western population. Specific regulations to restrict the use of TFA and interventions to promote public awareness of the health effects of TFA are recommended in Asian countries. Due to limited eligible studies that covered only six Asian countries, there remains cautious to generalize the findings to other Asian countries.
DegreeMaster of Public Health
SubjectTrans fatty acids
Cardiovascular system - Diseases
Dept/ProgramPublic Health
Persistent Identifierhttp://hdl.handle.net/10722/206974

 

DC FieldValueLanguage
dc.contributor.authorWang, Zherun-
dc.contributor.author王浙潤.王浙润-
dc.date.accessioned2014-12-04T23:17:24Z-
dc.date.available2014-12-04T23:17:24Z-
dc.date.issued2014-
dc.identifier.citationWang, Z. [王浙潤.王浙润]. (2014). Intake of trans fatty acid and risk of cardiovascular disease in Asian population : a systematic review. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b5320726-
dc.identifier.urihttp://hdl.handle.net/10722/206974-
dc.description.abstractBackground Many studies in western countries have suggested a positive association between intake of trans fatty acid (TFA) and risk of cardiovascular diseases (CVDs). In Asia, although intake of TFA was relatively low, it evidenced an increasing trend which was accompanied with an increasing prevalence of CVDs among the population. There was currently no systematic review on the relationship between intake of TFA and CVDs in Asian population. This systematic review was aimed to synthesize the association between intake of TFA and the risk of CVDs in Asian population from published literature. Methods Both English and Chinese literature published before 1st January 2014were retrieved from PubMed, Medline, Google scholaand CNKI with a combination of keywords. Studies that reported the associations between intake of TFA and CVD-related risks and those conducted among Asian population were included. The quality of eligible literature included in the review was assessed based on STROBE. Findings regarding the associations between intake of TFA and risk of CVDs were extracted and synthesized through comparing and evaluating the quality of findings across the included studies. Results Of the 378 articles retrieved from the datasets, nine studies were eligible to be included in this systematic review. The nine studies covered six Asian countries including Iran, China, Korea, Japan, Israel and India. Seven of nine studies indicated a positive association between intake of TFA and risk of CVDs while the other two reported no significant association. However, none of the included studies were interventional studies and only one was prospective cohort study. Conclusion The findings that more intake of TFA was associated with increased risk of CVDs in Asian population were consistent with that in the western population. Specific regulations to restrict the use of TFA and interventions to promote public awareness of the health effects of TFA are recommended in Asian countries. Due to limited eligible studies that covered only six Asian countries, there remains cautious to generalize the findings to other Asian countries.-
dc.languageeng-
dc.publisherThe University of Hong Kong (Pokfulam, Hong Kong)-
dc.relation.ispartofHKU Theses Online (HKUTO)-
dc.rightsThe author retains all proprietary rights, (such as patent rights) and the right to use in future works.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.lcshTrans fatty acids-
dc.subject.lcshCardiovascular system - Diseases-
dc.titleIntake of trans fatty acid and risk of cardiovascular disease in Asian population : a systematic review-
dc.typePG_Thesis-
dc.identifier.hkulb5320726-
dc.description.thesisnameMaster of Public Health-
dc.description.thesislevelMaster-
dc.description.thesisdisciplinePublic Health-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.5353/th_b5320726-

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