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Article: Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollution

TitleCancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollution
Authors
KeywordsAir pollution
Lung cancer
Head and neck cancer
Mutagenic effects
Issue Date2014
PublisherSun Yat-Sen University Cancer Center. The Journal's web site is located at http://www.cjcsysu.cn/
Citation
Chinese Journal of Cancer (English version), 2014, v. 33 n. 10, p. 476-480 How to Cite?
AbstractOutdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization(WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers—all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans.
Persistent Identifierhttp://hdl.handle.net/10722/205951
ISSN
2015 Impact Factor: 2.814
2015 SCImago Journal Rankings: 1.081
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, ICKen_US
dc.contributor.authorNg, YKen_US
dc.contributor.authorLui, WYVen_US
dc.date.accessioned2014-10-20T10:18:35Z-
dc.date.available2014-10-20T10:18:35Z-
dc.date.issued2014en_US
dc.identifier.citationChinese Journal of Cancer (English version), 2014, v. 33 n. 10, p. 476-480en_US
dc.identifier.issn1000-467X-
dc.identifier.urihttp://hdl.handle.net/10722/205951-
dc.description.abstractOutdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization(WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers—all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans.-
dc.languageengen_US
dc.publisherSun Yat-Sen University Cancer Center. The Journal's web site is located at http://www.cjcsysu.cn/-
dc.relation.ispartofChinese Journal of Canceren_US
dc.subjectAir pollution-
dc.subjectLung cancer-
dc.subjectHead and neck cancer-
dc.subjectMutagenic effects-
dc.titleCancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollutionen_US
dc.typeArticleen_US
dc.identifier.emailWong, ICK: wongick@hku.hken_US
dc.identifier.emailLui, WYV: vlui002@hku.hken_US
dc.identifier.authorityWong, ICK=rp01480en_US
dc.identifier.authorityLui, WYV=rp01876en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.5732/cjc.014.10093en_US
dc.identifier.pmid25011457-
dc.identifier.pmcidPMC4198750-
dc.identifier.scopuseid=2-s2.0-84907515798-
dc.identifier.hkuros241289en_US
dc.identifier.volume33en_US
dc.identifier.issue10en_US
dc.identifier.spage476en_US
dc.identifier.epage480en_US
dc.identifier.isiWOS:000342886800003-
dc.publisher.placeChina-

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