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- Publisher Website: 10.5732/cjc.014.10093
- Scopus: eid_2-s2.0-84907515798
- PMID: 25011457
- WOS: WOS:000342886800003
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Article: Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollution
Title | Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollution |
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Authors | |
Keywords | Air pollution Lung cancer Head and neck cancer Mutagenic effects |
Issue Date | 2014 |
Publisher | Sun Yat-Sen University Cancer Center. The Journal's web site is located at http://www.cjcsysu.cn/ |
Citation | Chinese Journal of Cancer (English version), 2014, v. 33 n. 10, p. 476-480 How to Cite? |
Abstract | Outdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization(WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers—all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans. |
Persistent Identifier | http://hdl.handle.net/10722/205951 |
ISSN | 2019 Impact Factor: 5.760 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wong, ICK | en_US |
dc.contributor.author | Ng, YK | en_US |
dc.contributor.author | Lui, WYV | en_US |
dc.date.accessioned | 2014-10-20T10:18:35Z | - |
dc.date.available | 2014-10-20T10:18:35Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Chinese Journal of Cancer (English version), 2014, v. 33 n. 10, p. 476-480 | en_US |
dc.identifier.issn | 1000-467X | - |
dc.identifier.uri | http://hdl.handle.net/10722/205951 | - |
dc.description.abstract | Outdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization(WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers—all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans. | - |
dc.language | eng | en_US |
dc.publisher | Sun Yat-Sen University Cancer Center. The Journal's web site is located at http://www.cjcsysu.cn/ | - |
dc.relation.ispartof | Chinese Journal of Cancer | en_US |
dc.subject | Air pollution | - |
dc.subject | Lung cancer | - |
dc.subject | Head and neck cancer | - |
dc.subject | Mutagenic effects | - |
dc.title | Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air Pollution | en_US |
dc.type | Article | en_US |
dc.identifier.email | Wong, ICK: wongick@hku.hk | en_US |
dc.identifier.email | Lui, WYV: vlui002@hku.hk | en_US |
dc.identifier.authority | Wong, ICK=rp01480 | en_US |
dc.identifier.authority | Lui, WYV=rp01876 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.5732/cjc.014.10093 | en_US |
dc.identifier.pmid | 25011457 | - |
dc.identifier.pmcid | PMC4198750 | - |
dc.identifier.scopus | eid_2-s2.0-84907515798 | - |
dc.identifier.hkuros | 241289 | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.spage | 476 | en_US |
dc.identifier.epage | 480 | en_US |
dc.identifier.isi | WOS:000342886800003 | - |
dc.publisher.place | China | - |
dc.identifier.issnl | 1000-467X | - |