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Conference Paper: Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro
Title | Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro |
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Authors | |
Keywords | Medical sciences |
Issue Date | 2014 |
Publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk |
Citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 31, abstract no. 46 How to Cite? |
Abstract | INTRODUCTION: Obstructive sleep apnoea is characterised by repetitive episodes of complete or partial upper airway collapse during sleep, leading to recurrent drop in arterial oxygenation (intermittent hypoxia [IH]) and sleep fragmentation. Repetitive IH with rapid reversal to normoxia initiates a series of pathological events such as oxidative stress, inflammation, and sympathetic activation, all of which contributes to endothelial dysfunction (a predictor and precursor of atherosclerosis). The aim of the current study was to investigate the effect of IH on the activation of endothelial cells in a cellular model in … |
Persistent Identifier | http://hdl.handle.net/10722/204301 |
ISSN | 2023 Impact Factor: 3.1 2023 SCImago Journal Rankings: 0.261 |
DC Field | Value | Language |
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dc.contributor.author | Lee, MYK | en_US |
dc.contributor.author | Mak, JCW | en_US |
dc.contributor.author | Ip, MSM | en_US |
dc.date.accessioned | 2014-09-19T21:43:26Z | - |
dc.date.available | 2014-09-19T21:43:26Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | The 19th Medical Research Conference (MRC 2014), Department of Medicine, The University of Hong Kong, Hong Kong, 18 January 2014. In Hong Kong Medical Journal, 2014, v. 20 suppl. 1, p. 31, abstract no. 46 | en_US |
dc.identifier.issn | 1024-2708 | - |
dc.identifier.uri | http://hdl.handle.net/10722/204301 | - |
dc.description.abstract | INTRODUCTION: Obstructive sleep apnoea is characterised by repetitive episodes of complete or partial upper airway collapse during sleep, leading to recurrent drop in arterial oxygenation (intermittent hypoxia [IH]) and sleep fragmentation. Repetitive IH with rapid reversal to normoxia initiates a series of pathological events such as oxidative stress, inflammation, and sympathetic activation, all of which contributes to endothelial dysfunction (a predictor and precursor of atherosclerosis). The aim of the current study was to investigate the effect of IH on the activation of endothelial cells in a cellular model in … | - |
dc.language | eng | en_US |
dc.publisher | Hong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk | - |
dc.relation.ispartof | Hong Kong Medical Journal | en_US |
dc.rights | Hong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press. | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Medical sciences | - |
dc.title | Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Lee, MYK: leemary@hku.hk | en_US |
dc.identifier.email | Mak, JCW: judithmak@hku.hk | en_US |
dc.identifier.email | Ip, MSM: msmip@hku.hk | en_US |
dc.identifier.authority | Mak, JCW=rp00352 | en_US |
dc.identifier.authority | Ip, MSM=rp00347 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.hkuros | 240403 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.issue | suppl. 1 | en_US |
dc.identifier.spage | 31 | en_US |
dc.identifier.epage | 31 | en_US |
dc.publisher.place | Hong Kong | - |
dc.identifier.issnl | 1024-2708 | - |