File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)

Article: Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction

TitleApplication of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction
Authors
Issue Date2014
Citation
Electrophoresis, 2014 How to Cite?
AbstractThe present work shows the application of the temperature-correlated mobility theory for the optimization of the separation and peak alignment of the main lignans from water extracts of traditional Chinese medicine Schisandra Chinensis Fructus as well as its prescription Yuye Decoction (Jade Fluid Decoction; YYD). This is the first application of this theory for MEKC separations, and the data presentation allows a much easier peak tracking and thereby identification of the analytes. Most interestingly, the data obtained and presented in the mobility scale at 298 K, show that Schisantherin A, which is easily mistaken as one of the analytes using traditional time scale, was actually not detected in Schisandra Chinensis Fructus and Yuye Decoction (Jade Fluid Decoction) water extracts. This proves the value of the temperature-correlated mobility scale for method optimization of complex samples. Thus, in the temperature-correlated mobility scale, the optimization of the system conditions for the MEKC separations can easily be achieved by correcting for viscosity changes. Also, the influence of the operating temperature can be monitored in a more distinct way.
Persistent Identifierhttp://hdl.handle.net/10722/203611

 

DC FieldValueLanguage
dc.contributor.authorLiu, Jen_US
dc.contributor.authorPetersen, NJen_US
dc.contributor.authorLee, CKFen_US
dc.contributor.authorHansen, SHen_US
dc.contributor.authorLao, Len_US
dc.contributor.authorSze, CWen_US
dc.contributor.authorZhang, Yen_US
dc.date.accessioned2014-09-19T15:32:35Z-
dc.date.available2014-09-19T15:32:35Z-
dc.date.issued2014en_US
dc.identifier.citationElectrophoresis, 2014en_US
dc.identifier.urihttp://hdl.handle.net/10722/203611-
dc.description.abstractThe present work shows the application of the temperature-correlated mobility theory for the optimization of the separation and peak alignment of the main lignans from water extracts of traditional Chinese medicine Schisandra Chinensis Fructus as well as its prescription Yuye Decoction (Jade Fluid Decoction; YYD). This is the first application of this theory for MEKC separations, and the data presentation allows a much easier peak tracking and thereby identification of the analytes. Most interestingly, the data obtained and presented in the mobility scale at 298 K, show that Schisantherin A, which is easily mistaken as one of the analytes using traditional time scale, was actually not detected in Schisandra Chinensis Fructus and Yuye Decoction (Jade Fluid Decoction) water extracts. This proves the value of the temperature-correlated mobility scale for method optimization of complex samples. Thus, in the temperature-correlated mobility scale, the optimization of the system conditions for the MEKC separations can easily be achieved by correcting for viscosity changes. Also, the influence of the operating temperature can be monitored in a more distinct way.en_US
dc.languageengen_US
dc.relation.ispartofElectrophoresisen_US
dc.titleApplication of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoctionen_US
dc.typeArticleen_US
dc.identifier.emailLee, CKF: ckflee@hku.hken_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.emailSze, CW: stephens@hku.hken_US
dc.identifier.emailZhang, Y: ybzhang@hku.hken_US
dc.identifier.authorityLee, CKF=rp00458en_US
dc.identifier.authorityLao, L=rp01784en_US
dc.identifier.authoritySze, CW=rp00514en_US
dc.identifier.authorityZhang, Y=rp01410en_US
dc.identifier.doi10.1002/elps.201400007en_US
dc.identifier.hkuros238931en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats