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Article: Megahertz all-optical swept-source optical coherence tomography based on broadband amplified optical time-stretch

TitleMegahertz all-optical swept-source optical coherence tomography based on broadband amplified optical time-stretch
Authors
Issue Date2014
PublisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3
Citation
Optics Letters, 2014, v. 39 n. 3, p. 622-625 How to Cite?
AbstractWe demonstrate all-optical ultrahigh-speed swept-source optical coherence tomography (OCT) based on amplified optical time-stretch (AOT). Such an inertia-free wavelength-swept mechanism, via group velocity dispersion, enables us to realize OCT with an A-scan rate well above MHz. More importantly, the key significance of AOT-OCT is its simultaneous broadband Raman amplification during the time-stretch process-greatly enhancing the detection sensitivity compared with prior attempts to apply optical time-stretch to OCT. Here, we report on an AOT-OCT system which is operated at an A-scan rate of 7.14 MHz, a superior roll-off performance (>2 mm/dB), a record-high sensitivity of time-stretch-based OCT (>80 dB) with a broadband gain bandwidth of 80 nm, which results in an axial resolution of approximately 15 mum. Our AOT-OCT system is thus able to, for the first time to the best of our knowledge, perform time-stretch-based OCT of biological tissue in vivo. It represents a major step forward in utilizing AOT as an alternative for achieving practical MHz OCT, without any long-term mechanical stability concerns as in typical swept-source OCT or bypassing the speed limitation of the image sensor employed in spectral-domain OCT.
Persistent Identifierhttp://hdl.handle.net/10722/202926
ISSN
2015 Impact Factor: 3.04
2015 SCImago Journal Rankings: 2.397
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorXu, Jen_US
dc.contributor.authorZhang, Cen_US
dc.contributor.authorXu, Jen_US
dc.contributor.authorWong, KKYen_US
dc.contributor.authorTsia, KKMen_US
dc.date.accessioned2014-09-19T10:10:38Z-
dc.date.available2014-09-19T10:10:38Z-
dc.date.issued2014en_US
dc.identifier.citationOptics Letters, 2014, v. 39 n. 3, p. 622-625en_US
dc.identifier.issn0146-9592-
dc.identifier.urihttp://hdl.handle.net/10722/202926-
dc.description.abstractWe demonstrate all-optical ultrahigh-speed swept-source optical coherence tomography (OCT) based on amplified optical time-stretch (AOT). Such an inertia-free wavelength-swept mechanism, via group velocity dispersion, enables us to realize OCT with an A-scan rate well above MHz. More importantly, the key significance of AOT-OCT is its simultaneous broadband Raman amplification during the time-stretch process-greatly enhancing the detection sensitivity compared with prior attempts to apply optical time-stretch to OCT. Here, we report on an AOT-OCT system which is operated at an A-scan rate of 7.14 MHz, a superior roll-off performance (>2 mm/dB), a record-high sensitivity of time-stretch-based OCT (>80 dB) with a broadband gain bandwidth of 80 nm, which results in an axial resolution of approximately 15 mum. Our AOT-OCT system is thus able to, for the first time to the best of our knowledge, perform time-stretch-based OCT of biological tissue in vivo. It represents a major step forward in utilizing AOT as an alternative for achieving practical MHz OCT, without any long-term mechanical stability concerns as in typical swept-source OCT or bypassing the speed limitation of the image sensor employed in spectral-domain OCT.-
dc.languageengen_US
dc.publisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3-
dc.relation.ispartofOptics Lettersen_US
dc.rightsOptics Letters. Copyright © Optical Society of America.-
dc.rightsThis paper was published in Optics Letters and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/ol/abstract.cfm?uri=ol-39-3-622. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshEye - cytology-
dc.subject.meshFingers-
dc.subject.meshFishes-
dc.subject.meshTime Factors-
dc.subject.meshTomography, Optical Coherence - methods-
dc.titleMegahertz all-optical swept-source optical coherence tomography based on broadband amplified optical time-stretchen_US
dc.typeArticleen_US
dc.identifier.emailWong, KKY: kywong04@hkucc.hku.hken_US
dc.identifier.emailTsia, KKM: tsia@hku.hken_US
dc.identifier.authorityWong, KKY=rp00189en_US
dc.identifier.authorityTsia, KKM=rp01389en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1364/OL.39.000622-
dc.identifier.pmid24487881-
dc.identifier.hkuros240546en_US
dc.identifier.hkuros236121-
dc.identifier.volume39en_US
dc.identifier.issue3-
dc.identifier.spage622en_US
dc.identifier.epage625en_US
dc.identifier.isiWOS:000330571200054-
dc.publisher.placeUnited States-

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