File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1039/c4ob00392f
- Scopus: eid_2-s2.0-84901269346
- PMID: 24788202
- WOS: WOS:000336802000001
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Development and application of serine/threonine ligation for synthetic protein chemistry
Title | Development and application of serine/threonine ligation for synthetic protein chemistry |
---|---|
Authors | |
Issue Date | 2014 |
Publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/obc |
Citation | Organic & Biomolecular Chemistry, 2014, v. 12 n. 23, p. 3768-3773 How to Cite? |
Abstract | Chemical synthesis of proteins, especially those with post-translational modifications, has offered new opportunities to study the protein structure–function relationship. In the past four years, we have developed the serine/threonine ligation (STL), which involves the chemoselective reaction between peptide salicylaldehyde esters and peptides with N-terminal serine or threonine. The method has been successfully applied to the synthesis of both linear and cyclic peptides/proteins. |
Persistent Identifier | http://hdl.handle.net/10722/202612 |
ISSN | 2023 Impact Factor: 2.9 2023 SCImago Journal Rankings: 0.607 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, H | - |
dc.contributor.author | Li, X | - |
dc.date.accessioned | 2014-09-19T08:42:32Z | - |
dc.date.available | 2014-09-19T08:42:32Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Organic & Biomolecular Chemistry, 2014, v. 12 n. 23, p. 3768-3773 | - |
dc.identifier.issn | 1477-0520 | - |
dc.identifier.uri | http://hdl.handle.net/10722/202612 | - |
dc.description.abstract | Chemical synthesis of proteins, especially those with post-translational modifications, has offered new opportunities to study the protein structure–function relationship. In the past four years, we have developed the serine/threonine ligation (STL), which involves the chemoselective reaction between peptide salicylaldehyde esters and peptides with N-terminal serine or threonine. The method has been successfully applied to the synthesis of both linear and cyclic peptides/proteins. | - |
dc.language | eng | - |
dc.publisher | Royal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/obc | - |
dc.relation.ispartof | Organic & Biomolecular Chemistry | - |
dc.title | Development and application of serine/threonine ligation for synthetic protein chemistry | - |
dc.type | Article | - |
dc.identifier.email | Liu, H: liuhan@hku.hk | - |
dc.identifier.email | Li, X: xuechenl@hku.hk | - |
dc.identifier.authority | Liu, H=rp02748 | - |
dc.identifier.authority | Li, X=rp00742 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1039/c4ob00392f | - |
dc.identifier.pmid | 24788202 | - |
dc.identifier.scopus | eid_2-s2.0-84901269346 | - |
dc.identifier.hkuros | 239977 | - |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 23 | - |
dc.identifier.spage | 3768 | - |
dc.identifier.epage | 3773 | - |
dc.identifier.isi | WOS:000336802000001 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1477-0520 | - |