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Conference Paper: Comparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma
Title | Comparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma |
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Authors | |
Issue Date | 2014 |
Publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021 |
Citation | The 2014 Joint International Congress of ILTS, ELITA and LICAGE, London, UK., 4-7 June 2014. In Liver Transplantation, 2014, v. 20 suppl. S1, p. S186, abstract no. P-115 How to Cite? |
Abstract | BACKGROUND: Previous studies described inferior long-term outcomes among HCV related HCC patients after liver resection and liver transplantation (LT). This study aims to evaluate the impact of HCV and HBV status on overall survival and recurrence in HCC patients after LT. METHOD: This was a retrospective study at a university centre. Data was retrieved from a prospectively collected database. All HCC patients who underwent LT from 1991 to 2012 were analyzed. RESULTS: Two hundred and thirty nine patients, of whom 207 had HBV and 32 had HCV underwent LT. Patients’ baseline demographic and tumor characteristics were listed in table 1. The 1-, 3, and 5-year patient survival were 97.0 vs. 90.3%, 86.5 vs. 86.4% and 79.4 vs. 86.4% in HBV and HCV patients respectively (p=0.584). The overall graft survival at 1-, 3- and 5-year were 96.5 vs. 87.1%, 86 vs. 87.1% and 78.9 vs. 87.1% for HBV and HCV patients respectively (p=0.546). 35/207 HBV patients (16.9%) and no HCV patient developed HCC recurrence. Majority (27/41) of patients in HBV group died as a result of HCC recurrence. In HCV group, 2 died as a result of reactivation and 2 died of sepsis. CONCLUSION: Etiology of underlying cirrhosis has no impact on overall patient and graft survival in HCC patients after LT. |
Description | Poster Session 1 - Malignancies: P-115 This free journal suppl. entitled: The ILTS 20th Annual International Congress |
Persistent Identifier | http://hdl.handle.net/10722/201366 |
ISSN | 2023 Impact Factor: 4.7 2023 SCImago Journal Rankings: 1.700 |
DC Field | Value | Language |
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dc.contributor.author | Wong, CLT | - |
dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Cheung, TT | - |
dc.contributor.author | Chan, ACY | - |
dc.contributor.author | Fung, JYY | - |
dc.contributor.author | Sharr, W | - |
dc.contributor.author | Tsang, SHY | - |
dc.contributor.author | Dai, WC | - |
dc.contributor.author | Chan, SC | - |
dc.contributor.author | Lo, CM | - |
dc.date.accessioned | 2014-08-21T07:25:25Z | - |
dc.date.available | 2014-08-21T07:25:25Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | The 2014 Joint International Congress of ILTS, ELITA and LICAGE, London, UK., 4-7 June 2014. In Liver Transplantation, 2014, v. 20 suppl. S1, p. S186, abstract no. P-115 | - |
dc.identifier.issn | 1527-6465 | - |
dc.identifier.uri | http://hdl.handle.net/10722/201366 | - |
dc.description | Poster Session 1 - Malignancies: P-115 | - |
dc.description | This free journal suppl. entitled: The ILTS 20th Annual International Congress | - |
dc.description.abstract | BACKGROUND: Previous studies described inferior long-term outcomes among HCV related HCC patients after liver resection and liver transplantation (LT). This study aims to evaluate the impact of HCV and HBV status on overall survival and recurrence in HCC patients after LT. METHOD: This was a retrospective study at a university centre. Data was retrieved from a prospectively collected database. All HCC patients who underwent LT from 1991 to 2012 were analyzed. RESULTS: Two hundred and thirty nine patients, of whom 207 had HBV and 32 had HCV underwent LT. Patients’ baseline demographic and tumor characteristics were listed in table 1. The 1-, 3, and 5-year patient survival were 97.0 vs. 90.3%, 86.5 vs. 86.4% and 79.4 vs. 86.4% in HBV and HCV patients respectively (p=0.584). The overall graft survival at 1-, 3- and 5-year were 96.5 vs. 87.1%, 86 vs. 87.1% and 78.9 vs. 87.1% for HBV and HCV patients respectively (p=0.546). 35/207 HBV patients (16.9%) and no HCV patient developed HCC recurrence. Majority (27/41) of patients in HBV group died as a result of HCC recurrence. In HCV group, 2 died as a result of reactivation and 2 died of sepsis. CONCLUSION: Etiology of underlying cirrhosis has no impact on overall patient and graft survival in HCC patients after LT. | - |
dc.language | eng | - |
dc.publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021 | - |
dc.relation.ispartof | Liver Transplantation | - |
dc.rights | Liver Transplantation. Copyright © John Wiley & Sons, Inc. | - |
dc.title | Comparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Wong, CLT: wongtcl@hku.hk | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.email | Cheung, TT: cheung68@hku.hk | - |
dc.identifier.email | Chan, ACY: acchan@hku.hk | - |
dc.identifier.email | Fung, JYY: jfung@hkucc.hku.hk | - |
dc.identifier.email | Sharr, W: wwsharr@hku.hk | - |
dc.identifier.email | Dai, WC: daiwc@hku.hk | - |
dc.identifier.email | Chan, SC: chanlsc@hkucc.hku.hk | - |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | - |
dc.identifier.authority | Wong, CLT=rp01679 | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.identifier.authority | Cheung, TT=rp02129 | - |
dc.identifier.authority | Chan, ACY=rp00310 | - |
dc.identifier.authority | Fung, JYY=rp00518 | - |
dc.identifier.authority | Chan, SC=rp01568 | - |
dc.identifier.authority | Lo, CM=rp00412 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1002/lt.23901 | - |
dc.identifier.scopus | eid_2-s2.0-84932186609 | - |
dc.identifier.hkuros | 234462 | - |
dc.identifier.volume | 20 | - |
dc.identifier.issue | suppl. S1 | - |
dc.identifier.spage | S186, abstract no. P-115 | - |
dc.identifier.epage | S186, abstract no. P-115 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1527-6465 | - |