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Conference Paper: Comparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma

TitleComparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma
Authors
Issue Date2014
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021
Citation
The 2014 Joint International Congress of ILTS, ELITA and LICAGE, London, UK., 4-7 June 2014. In Liver Transplantation, 2014, v. 20 suppl. S1, p. S186, abstract no. P-115 How to Cite?
AbstractBACKGROUND: Previous studies described inferior long-term outcomes among HCV related HCC patients after liver resection and liver transplantation (LT). This study aims to evaluate the impact of HCV and HBV status on overall survival and recurrence in HCC patients after LT. METHOD: This was a retrospective study at a university centre. Data was retrieved from a prospectively collected database. All HCC patients who underwent LT from 1991 to 2012 were analyzed. RESULTS: Two hundred and thirty nine patients, of whom 207 had HBV and 32 had HCV underwent LT. Patients’ baseline demographic and tumor characteristics were listed in table 1. The 1-, 3, and 5-year patient survival were 97.0 vs. 90.3%, 86.5 vs. 86.4% and 79.4 vs. 86.4% in HBV and HCV patients respectively (p=0.584). The overall graft survival at 1-, 3- and 5-year were 96.5 vs. 87.1%, 86 vs. 87.1% and 78.9 vs. 87.1% for HBV and HCV patients respectively (p=0.546). 35/207 HBV patients (16.9%) and no HCV patient developed HCC recurrence. Majority (27/41) of patients in HBV group died as a result of HCC recurrence. In HCV group, 2 died as a result of reactivation and 2 died of sepsis. CONCLUSION: Etiology of underlying cirrhosis has no impact on overall patient and graft survival in HCC patients after LT.
DescriptionPoster Session 1 - Malignancies: P-115
This free journal suppl. entitled: The ILTS 20th Annual International Congress
Persistent Identifierhttp://hdl.handle.net/10722/201366
ISSN
2015 Impact Factor: 3.951
2015 SCImago Journal Rankings: 1.763

 

DC FieldValueLanguage
dc.contributor.authorWong, CLT-
dc.contributor.authorChok, KSH-
dc.contributor.authorCheung, TT-
dc.contributor.authorChan, ACY-
dc.contributor.authorFung, JYY-
dc.contributor.authorSharr, W-
dc.contributor.authorTsang, SHY-
dc.contributor.authorDai, WC-
dc.contributor.authorChan, SC-
dc.contributor.authorLo, CM-
dc.date.accessioned2014-08-21T07:25:25Z-
dc.date.available2014-08-21T07:25:25Z-
dc.date.issued2014-
dc.identifier.citationThe 2014 Joint International Congress of ILTS, ELITA and LICAGE, London, UK., 4-7 June 2014. In Liver Transplantation, 2014, v. 20 suppl. S1, p. S186, abstract no. P-115-
dc.identifier.issn1527-6465-
dc.identifier.urihttp://hdl.handle.net/10722/201366-
dc.descriptionPoster Session 1 - Malignancies: P-115-
dc.descriptionThis free journal suppl. entitled: The ILTS 20th Annual International Congress-
dc.description.abstractBACKGROUND: Previous studies described inferior long-term outcomes among HCV related HCC patients after liver resection and liver transplantation (LT). This study aims to evaluate the impact of HCV and HBV status on overall survival and recurrence in HCC patients after LT. METHOD: This was a retrospective study at a university centre. Data was retrieved from a prospectively collected database. All HCC patients who underwent LT from 1991 to 2012 were analyzed. RESULTS: Two hundred and thirty nine patients, of whom 207 had HBV and 32 had HCV underwent LT. Patients’ baseline demographic and tumor characteristics were listed in table 1. The 1-, 3, and 5-year patient survival were 97.0 vs. 90.3%, 86.5 vs. 86.4% and 79.4 vs. 86.4% in HBV and HCV patients respectively (p=0.584). The overall graft survival at 1-, 3- and 5-year were 96.5 vs. 87.1%, 86 vs. 87.1% and 78.9 vs. 87.1% for HBV and HCV patients respectively (p=0.546). 35/207 HBV patients (16.9%) and no HCV patient developed HCC recurrence. Majority (27/41) of patients in HBV group died as a result of HCC recurrence. In HCV group, 2 died as a result of reactivation and 2 died of sepsis. CONCLUSION: Etiology of underlying cirrhosis has no impact on overall patient and graft survival in HCC patients after LT.-
dc.languageeng-
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021-
dc.relation.ispartofLiver Transplantation-
dc.rightsLiver Transplantation. Copyright © John Wiley & Sons, Inc.-
dc.titleComparisons of surgical outcomes and recurrence after liver transplantation in patients with Hepatitis B vs. Hepatitis C related hepatocellular carcinoma-
dc.typeConference_Paper-
dc.identifier.emailWong, CLT: wongtcl@hku.hk-
dc.identifier.emailChok, KSH: chok6275@hku.hk-
dc.identifier.emailCheung, TT: cheung68@hku.hk-
dc.identifier.emailChan, ACY: acchan@hku.hk-
dc.identifier.emailFung, JYY: jfung@hkucc.hku.hk-
dc.identifier.emailSharr, W: wwsharr@hku.hk-
dc.identifier.emailDai, WC: daiwc@hku.hk-
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hk-
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hk-
dc.identifier.authorityWong, CLT=rp01679-
dc.identifier.authorityChok, KSH=rp02110-
dc.identifier.authorityCheung, TT=rp02129-
dc.identifier.authorityChan, ACY=rp00310-
dc.identifier.authorityFung, JYY=rp00518-
dc.identifier.authorityChan, SC=rp01568-
dc.identifier.authorityLo, CM=rp00412-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1002/lt.23901-
dc.identifier.hkuros234462-
dc.identifier.volume20-
dc.identifier.issuesuppl. S1-
dc.identifier.spageS186, abstract no. P-115-
dc.identifier.epageS186, abstract no. P-115-
dc.publisher.placeUnited States-

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