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Article: Quantifying the burden of disease due to premature mortality in Hong Kong using Standard Expected Years of Life Lost

TitleQuantifying the burden of disease due to premature mortality in Hong Kong using Standard Expected Years of Life Lost
Authors
Issue Date2013
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/
Citation
BMC Public Health , 2013, v. 13, article no. 863 How to Cite?
AbstractBACKGROUND: To complement available information on mortality in a population Standard Expected Years of Life Lost (SEYLL), an indicator of premature mortality, is increasingly used to calculate the mortality-associated disease burden. SEYLL consider the age at death and therefore allow a more accurate view on mortality patterns as compared to routinely used measures (e.g. death counts). This study provides a comprehensive assessment of disease and injury SEYLL for Hong Kong in 2010. METHODS: To estimate the SEYLL, life-expectancy at birth was set according to the 2004 Global Burden of Disease study at 82.5 and 80 years for females and males, respectively. Cause of death data for 2010 were corrected for misclassification of cardiovascular and cancer causes. In addition to the baseline estimates, scenario analyses were performed using alternative assumptions on life-expectancy (Hong Kong standard life-expectancy), time-discounting and age-weighting. To estimate a trend of premature mortality a time-series analysis from 2001 to 2010 was conducted. RESULTS: In 2010 524,706.5 years were lost due to premature death in Hong Kong with 58.3% of the SEYLL attributable to male deaths. The three overall leading single causes of SEYLL were 'trachea, bronchus and lung cancers', 'ischaemic heart disease' and 'lower respiratory infections' together accounting for about 29% of the overall SEYLL. Further, self-inflicted injuries (5.6%; ranked 5) and liver cancer (4.9%; ranked 7) were identified as important causes not adequately captured by classical mortality measures. Scenario analyses highlighted that by using a 3% time-discount rate and non-uniform age-weights the SEYLL dropped by 51.6%. Using Hong Kong's standard life-expectancy values resulted in an overall increase of SEYLL by 10.8% as compared to the baseline SEYLL. Time-series analysis indicates an overall increase of SEYLL by 6.4%. In particular, group I (communicable, maternal, perinatal and nutritional) conditions showed highest increases with SEYLL-rates per 100,000 in 2010 being 1.4 times higher than 2001. CONCLUSIONS: The study stresses the mortality impact of diseases and injuries that occur in earlier stages of life and thus presents the SEYLL measure as a more sensitive indicator compared to classical mortality indicators. SEYLL provide useful additional information and supplement available death statistics.
Persistent Identifierhttp://hdl.handle.net/10722/201036
ISSN
2015 Impact Factor: 2.209
2015 SCImago Journal Rankings: 1.372
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPlass, Den_US
dc.contributor.authorChau, PYKen_US
dc.contributor.authorThach, TQen_US
dc.contributor.authorJahn, HJen_US
dc.contributor.authorLai, PCen_US
dc.contributor.authorWong, CMen_US
dc.contributor.authorKraemer, Aen_US
dc.date.accessioned2014-08-21T07:10:34Z-
dc.date.available2014-08-21T07:10:34Z-
dc.date.issued2013en_US
dc.identifier.citationBMC Public Health , 2013, v. 13, article no. 863en_US
dc.identifier.issn1471-2458-
dc.identifier.urihttp://hdl.handle.net/10722/201036-
dc.description.abstractBACKGROUND: To complement available information on mortality in a population Standard Expected Years of Life Lost (SEYLL), an indicator of premature mortality, is increasingly used to calculate the mortality-associated disease burden. SEYLL consider the age at death and therefore allow a more accurate view on mortality patterns as compared to routinely used measures (e.g. death counts). This study provides a comprehensive assessment of disease and injury SEYLL for Hong Kong in 2010. METHODS: To estimate the SEYLL, life-expectancy at birth was set according to the 2004 Global Burden of Disease study at 82.5 and 80 years for females and males, respectively. Cause of death data for 2010 were corrected for misclassification of cardiovascular and cancer causes. In addition to the baseline estimates, scenario analyses were performed using alternative assumptions on life-expectancy (Hong Kong standard life-expectancy), time-discounting and age-weighting. To estimate a trend of premature mortality a time-series analysis from 2001 to 2010 was conducted. RESULTS: In 2010 524,706.5 years were lost due to premature death in Hong Kong with 58.3% of the SEYLL attributable to male deaths. The three overall leading single causes of SEYLL were 'trachea, bronchus and lung cancers', 'ischaemic heart disease' and 'lower respiratory infections' together accounting for about 29% of the overall SEYLL. Further, self-inflicted injuries (5.6%; ranked 5) and liver cancer (4.9%; ranked 7) were identified as important causes not adequately captured by classical mortality measures. Scenario analyses highlighted that by using a 3% time-discount rate and non-uniform age-weights the SEYLL dropped by 51.6%. Using Hong Kong's standard life-expectancy values resulted in an overall increase of SEYLL by 10.8% as compared to the baseline SEYLL. Time-series analysis indicates an overall increase of SEYLL by 6.4%. In particular, group I (communicable, maternal, perinatal and nutritional) conditions showed highest increases with SEYLL-rates per 100,000 in 2010 being 1.4 times higher than 2001. CONCLUSIONS: The study stresses the mortality impact of diseases and injuries that occur in earlier stages of life and thus presents the SEYLL measure as a more sensitive indicator compared to classical mortality indicators. SEYLL provide useful additional information and supplement available death statistics.-
dc.languageengen_US
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcpublichealth/en_US
dc.relation.ispartofBMC Public Healthen_US
dc.rightsBMC Public Health . Copyright © BioMed Central Ltd.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleQuantifying the burden of disease due to premature mortality in Hong Kong using Standard Expected Years of Life Losten_US
dc.typeArticleen_US
dc.identifier.emailChau, PYK: ykchau@hkucc.hku.hken_US
dc.identifier.emailThach, TQ: thach@hku.hken_US
dc.identifier.emailLai, PC: pclai@hku.hken_US
dc.identifier.emailWong, CM: hrmrwcm@hku.hken_US
dc.identifier.authorityThach, TQ=rp00450en_US
dc.identifier.authorityLai, PC=rp00565en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/1471-2458-13-863-
dc.identifier.pmid24044523-
dc.identifier.pmcidPMC3848717-
dc.identifier.hkuros234284en_US
dc.identifier.volume13, article no. 863en_US
dc.identifier.isiWOS:000324728300001-
dc.publisher.placeUnited Kingdomen_US

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