File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: Uptake of antigens from the intestine by dendritic cells

TitleUptake of antigens from the intestine by dendritic cells
Authors
KeywordsLymph
Lymph node
Rat
TSE
Antigen uptake
Dendritic cell
Intestine
Migration
Peyer's patch
Prions
Scrapie
Issue Date2004
Citation
Annals of the New York Academy of Sciences, 2004, v. 1029, p. 75-82 How to Cite?
AbstractThe intestinal immune system responds to ingested antigens in a variety of ways, ranging from tolerance to full immunity. How T cells are instructed to make these differential responses is still unclear. Dendritic cells (DCs) sample enteric antigens in the lamina propria and Peyer's patches, and transport them within the patch or to mesenteric nodes where they are presented to lymphocytes. It is probable that DCs also transmit information that influences the outcome of T cell activation, but the nature of this information and the factors in the intestine that regulate DC behavior and properties are far from clear. We have developed a model in the rat that permits analysis of DCs actually in the process of migration from the intestine to mesenteric nodes. In this paper we will review those aspects of our research that relate to antigen uptake and discuss these in the contest of other experimental systems. © 2004 New York Academy of Sciences.
DescriptionThis journal vol. entitled: Oral Tolerance: New Insights and Prospects for Clinical Application
Second conference on oral tolerance
Persistent Identifierhttp://hdl.handle.net/10722/199900
ISSN
2015 Impact Factor: 4.518
2015 SCImago Journal Rankings: 2.389
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMacPherson, Gordon Gordon-
dc.contributor.authorMilling, Simon W F-
dc.contributor.authorYrlid, Ulf-
dc.contributor.authorCousins, Lesley-
dc.contributor.authorTurnbull, Emma L.-
dc.contributor.authorHuang, Fangping-
dc.date.accessioned2014-07-26T23:10:53Z-
dc.date.available2014-07-26T23:10:53Z-
dc.date.issued2004-
dc.identifier.citationAnnals of the New York Academy of Sciences, 2004, v. 1029, p. 75-82-
dc.identifier.issn0077-8923-
dc.identifier.urihttp://hdl.handle.net/10722/199900-
dc.descriptionThis journal vol. entitled: Oral Tolerance: New Insights and Prospects for Clinical Application-
dc.descriptionSecond conference on oral tolerance-
dc.description.abstractThe intestinal immune system responds to ingested antigens in a variety of ways, ranging from tolerance to full immunity. How T cells are instructed to make these differential responses is still unclear. Dendritic cells (DCs) sample enteric antigens in the lamina propria and Peyer's patches, and transport them within the patch or to mesenteric nodes where they are presented to lymphocytes. It is probable that DCs also transmit information that influences the outcome of T cell activation, but the nature of this information and the factors in the intestine that regulate DC behavior and properties are far from clear. We have developed a model in the rat that permits analysis of DCs actually in the process of migration from the intestine to mesenteric nodes. In this paper we will review those aspects of our research that relate to antigen uptake and discuss these in the contest of other experimental systems. © 2004 New York Academy of Sciences.-
dc.languageeng-
dc.relation.ispartofAnnals of the New York Academy of Sciences-
dc.subjectLymph-
dc.subjectLymph node-
dc.subjectRat-
dc.subjectTSE-
dc.subjectAntigen uptake-
dc.subjectDendritic cell-
dc.subjectIntestine-
dc.subjectMigration-
dc.subjectPeyer's patch-
dc.subjectPrions-
dc.subjectScrapie-
dc.titleUptake of antigens from the intestine by dendritic cells-
dc.typeConference_Paper-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1196/annals.1309.010-
dc.identifier.pmid15681746-
dc.identifier.scopuseid_2-s2.0-14544271343-
dc.identifier.volume1029-
dc.identifier.spage75-
dc.identifier.epage82-
dc.identifier.isiWOS:000227728600010-
dc.customcontrol.immutablesml 160704 amended-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats