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Conference Paper: Preventing and arresting root caries through silver diammine fluoride applications

TitlePreventing and arresting root caries through silver diammine fluoride applications
Authors
KeywordsCaries
Clinical trials
Fluoride and Gerontology
Issue Date2014
PublisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
The 92nd General Session & Exhibition of the International Association for Dental Research (IADR), Cape Town, South Africa, 25-28 June 2014. In Journal of Dental Research, 2014, v. 93 n. Special issue B: abstract no. 192 How to Cite?
AbstractObjectives: To describe the effectiveness of application of silver diammine fluoride (SDF) solution in preventing and arresting root caries in elders. Method: This study was conducted among community-dwelling elders aged over 55 years in Hong Kong. Elders having self-care ability for normal daily activities and at least 5 teeth with exposed root surfaces were randomly allocated into 3 groups to receive interventions as follows: Gp1 –oral hygiene instruction (OHI) only; Gp2 – OHI and annual application of SDF solution; Gp3 – OHI and annual application of SDF solution followed immediately by potassium iodide solution. Fluoridated toothpaste (1000 ppm) was provided to all subjects. Status of root surfaces was assessed at baseline and thereafter every 6 months by the same independent examiner. Results: A total of 323 elders aged 56-87 years (mean=72.1) with 13676 exposed root surfaces were examined at baseline. After 12 months, 297 (92%) of the elders were reviewed. The mean numbers of root surface with new caries in Gp1 to Gp3 were 0.47, 0.18, 0.23, respectively (ANOVA, p<0.05). Elders received SDF and SDF followed by potassium iodide solution developed fewer new root surface caries than those only received OHI (Scheffe’s multiple comparison, p<0.05). The numbers of surface with active caries at baseline were 40, 54 and 62, in Gp1 to Gp3, respectively. The proportions of them been arrested 12 months after treatment were 22.5%, 44.4%, 66.1% in Gp1 to Gp3, respectively (X2 test, P<0.001). Pairwise comparisons showed statistically significant differences among all the pairs (P<0.05). Conclusions: The initial 12-month results support that SDF solution is effective in preventing and arresting root caries. This clinical trial is on-going and longer term results will be reported later. (Supported by Hong Kong Research Grants Council, grant #HKU773711M) This abstract is based on research that was funded entirely or partially by an outside source: Hong Kong Research Grants Council, grant #HKU773711M
DescriptionOral Presentation
Session 51: Implications of Caries Risk and Caries Early Management
Persistent Identifierhttp://hdl.handle.net/10722/199324
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714

 

DC FieldValueLanguage
dc.contributor.authorLi, Ren_US
dc.contributor.authorLo, ECMen_US
dc.contributor.authorChu, CHen_US
dc.contributor.authorLiu, Ben_US
dc.date.accessioned2014-07-22T01:13:37Z-
dc.date.available2014-07-22T01:13:37Z-
dc.date.issued2014en_US
dc.identifier.citationThe 92nd General Session & Exhibition of the International Association for Dental Research (IADR), Cape Town, South Africa, 25-28 June 2014. In Journal of Dental Research, 2014, v. 93 n. Special issue B: abstract no. 192en_US
dc.identifier.issn0022-0345-
dc.identifier.urihttp://hdl.handle.net/10722/199324-
dc.descriptionOral Presentation-
dc.descriptionSession 51: Implications of Caries Risk and Caries Early Management-
dc.description.abstractObjectives: To describe the effectiveness of application of silver diammine fluoride (SDF) solution in preventing and arresting root caries in elders. Method: This study was conducted among community-dwelling elders aged over 55 years in Hong Kong. Elders having self-care ability for normal daily activities and at least 5 teeth with exposed root surfaces were randomly allocated into 3 groups to receive interventions as follows: Gp1 –oral hygiene instruction (OHI) only; Gp2 – OHI and annual application of SDF solution; Gp3 – OHI and annual application of SDF solution followed immediately by potassium iodide solution. Fluoridated toothpaste (1000 ppm) was provided to all subjects. Status of root surfaces was assessed at baseline and thereafter every 6 months by the same independent examiner. Results: A total of 323 elders aged 56-87 years (mean=72.1) with 13676 exposed root surfaces were examined at baseline. After 12 months, 297 (92%) of the elders were reviewed. The mean numbers of root surface with new caries in Gp1 to Gp3 were 0.47, 0.18, 0.23, respectively (ANOVA, p<0.05). Elders received SDF and SDF followed by potassium iodide solution developed fewer new root surface caries than those only received OHI (Scheffe’s multiple comparison, p<0.05). The numbers of surface with active caries at baseline were 40, 54 and 62, in Gp1 to Gp3, respectively. The proportions of them been arrested 12 months after treatment were 22.5%, 44.4%, 66.1% in Gp1 to Gp3, respectively (X2 test, P<0.001). Pairwise comparisons showed statistically significant differences among all the pairs (P<0.05). Conclusions: The initial 12-month results support that SDF solution is effective in preventing and arresting root caries. This clinical trial is on-going and longer term results will be reported later. (Supported by Hong Kong Research Grants Council, grant #HKU773711M) This abstract is based on research that was funded entirely or partially by an outside source: Hong Kong Research Grants Council, grant #HKU773711M-
dc.languageengen_US
dc.publisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925-
dc.relation.ispartofJournal of Dental Researchen_US
dc.rightsJournal of Dental Research. Copyright © Sage Publications, Inc.-
dc.subjectCaries-
dc.subjectClinical trials-
dc.subjectFluoride and Gerontology-
dc.titlePreventing and arresting root caries through silver diammine fluoride applicationsen_US
dc.typeConference_Paperen_US
dc.identifier.emailLo, ECM: edward-lo@hku.hken_US
dc.identifier.emailChu, CH: chchu@hku.hken_US
dc.identifier.emailLiu, B: smilelby@hku.hken_US
dc.identifier.authorityLo, ECM=rp00015en_US
dc.identifier.authorityChu, CH=rp00022en_US
dc.identifier.hkuros231058en_US
dc.identifier.volume93en_US
dc.identifier.issueSpecial issue B: abstract no. 192en_US
dc.publisher.placeUnited States-

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