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Article: Performing Kasai portoenterostomy beyond 60 days of life is not necessarily associated with a worse outcome

TitlePerforming Kasai portoenterostomy beyond 60 days of life is not necessarily associated with a worse outcome
Authors
Issue Date2010
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jpgn.org
Citation
Journal of Pediatric Gastroenterology and Nutrition, 2010, v. 51 n. 5, p. 631-634 How to Cite?
AbstractThe introduction of Kasai portoenterostomy has dramatically improved the management and survival of children with biliary atresia. The success rate of this operation worldwide varies with different centers. In this respect, many authors have studied the correlation of a successful outcome with various factors, such as the experience and workload of the surgical center, the use of postoperative steroids, the underlying biliary anatomy, as well as the age of patients at the time of the operation. Indeed, the age of 60 days has been used by clinicians as a critical time beyond which the rate of success of the Kasai operation markedly reduces. Despite this worldwide adoption, clear evidence supporting this critical operative time is still lacking. We undertook a review of our experience in the management of children with biliary atresia and focused specifically on the issue of the timing of operation. We showed that performing the Kasai operation beyond the age of 60 days was not associated with a worse outcome and that a high percentage of patients could still achieve good bile flow with normal bilirubin postoperatively. Thus, we believe that until the age of 100 days, the age of the patients does not play a significant role in determining the success of the Kasai operation.
Persistent Identifierhttp://hdl.handle.net/10722/197257
ISSN
2015 Impact Factor: 2.4
2015 SCImago Journal Rankings: 1.227
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, KKYen_US
dc.contributor.authorChung, HYen_US
dc.contributor.authorChan, IHYen_US
dc.contributor.authorLan, LCLen_US
dc.contributor.authorTam, PKHen_US
dc.date.accessioned2014-05-23T02:30:05Z-
dc.date.available2014-05-23T02:30:05Z-
dc.date.issued2010en_US
dc.identifier.citationJournal of Pediatric Gastroenterology and Nutrition, 2010, v. 51 n. 5, p. 631-634en_US
dc.identifier.issn0277-2116-
dc.identifier.urihttp://hdl.handle.net/10722/197257-
dc.description.abstractThe introduction of Kasai portoenterostomy has dramatically improved the management and survival of children with biliary atresia. The success rate of this operation worldwide varies with different centers. In this respect, many authors have studied the correlation of a successful outcome with various factors, such as the experience and workload of the surgical center, the use of postoperative steroids, the underlying biliary anatomy, as well as the age of patients at the time of the operation. Indeed, the age of 60 days has been used by clinicians as a critical time beyond which the rate of success of the Kasai operation markedly reduces. Despite this worldwide adoption, clear evidence supporting this critical operative time is still lacking. We undertook a review of our experience in the management of children with biliary atresia and focused specifically on the issue of the timing of operation. We showed that performing the Kasai operation beyond the age of 60 days was not associated with a worse outcome and that a high percentage of patients could still achieve good bile flow with normal bilirubin postoperatively. Thus, we believe that until the age of 100 days, the age of the patients does not play a significant role in determining the success of the Kasai operation.-
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.jpgn.org-
dc.relation.ispartofJournal of Pediatric Gastroenterology and Nutritionen_US
dc.subject.meshAge Factors-
dc.subject.meshBile Ducts - surgery-
dc.subject.meshBiliary Atresia - surgery-
dc.subject.meshPortoenterostomy, Hepatic - methods-
dc.titlePerforming Kasai portoenterostomy beyond 60 days of life is not necessarily associated with a worse outcomeen_US
dc.typeArticleen_US
dc.identifier.emailWong, KKY: kkywong@hkucc.hku.hken_US
dc.identifier.emailLan, LCL: lancll@HKUCC-COM.hku.hken_US
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_US
dc.identifier.authorityWong, KKY=rp01392en_US
dc.identifier.authorityTam, PKH=rp00060en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/MPG.0b013e3181e8e194-
dc.identifier.pmid20818266-
dc.identifier.scopuseid_2-s2.0-78149286016-
dc.identifier.hkuros183846en_US
dc.identifier.volume51en_US
dc.identifier.issue5en_US
dc.identifier.spage631en_US
dc.identifier.epage634en_US
dc.identifier.isiWOS:000283536900016-
dc.publisher.placeUnited States-

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