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Article: Pulmonary Alveolar Proteinosis in Extremis: The Case for Aggressive Whole Lung Lavage with Extracorporeal Membrane Oxygenation Support

TitlePulmonary Alveolar Proteinosis in Extremis: The Case for Aggressive Whole Lung Lavage with Extracorporeal Membrane Oxygenation Support
Authors
Issue Date2008
Citation
Heart Lung and Circulation, 2008, v. 17 n. 1, p. 69-72 How to Cite?
AbstractPulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous material is deposited in the alveoli, compromising gaseous exchange. We report the case of a 29-year-old female patient presenting with the most extreme case of PAP yet reported. She successfully managed by aggressive bilateral whole lung lavage (WLL) in a single sitting using extracorporeal membrane oxygenation (ECMO) support. Despite critical hypercarbia and ventilator-dependence for 12 days before lavage, the patient experienced rapid recovery of pulmonary function after WLL and ECMO could be discontinued on-table. Aggressive WLL with ECMO support can be safe and effective even in the most severe cases of PAP. © 2006 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand.
Persistent Identifierhttp://hdl.handle.net/10722/196676
ISSN
2015 Impact Factor: 1.575
2015 SCImago Journal Rankings: 0.567
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSihoe, ADL-
dc.contributor.authorNg, VMW-
dc.contributor.authorLiu, RWT-
dc.contributor.authorCheng, L-C-
dc.date.accessioned2014-04-24T02:10:33Z-
dc.date.available2014-04-24T02:10:33Z-
dc.date.issued2008-
dc.identifier.citationHeart Lung and Circulation, 2008, v. 17 n. 1, p. 69-72-
dc.identifier.issn1443-9506-
dc.identifier.urihttp://hdl.handle.net/10722/196676-
dc.description.abstractPulmonary alveolar proteinosis (PAP) is a rare disorder in which lipoproteinaceous material is deposited in the alveoli, compromising gaseous exchange. We report the case of a 29-year-old female patient presenting with the most extreme case of PAP yet reported. She successfully managed by aggressive bilateral whole lung lavage (WLL) in a single sitting using extracorporeal membrane oxygenation (ECMO) support. Despite critical hypercarbia and ventilator-dependence for 12 days before lavage, the patient experienced rapid recovery of pulmonary function after WLL and ECMO could be discontinued on-table. Aggressive WLL with ECMO support can be safe and effective even in the most severe cases of PAP. © 2006 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand.-
dc.languageeng-
dc.relation.ispartofHeart Lung and Circulation-
dc.titlePulmonary Alveolar Proteinosis in Extremis: The Case for Aggressive Whole Lung Lavage with Extracorporeal Membrane Oxygenation Support-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.hlc.2006.11.007-
dc.identifier.pmid17337244-
dc.identifier.scopuseid_2-s2.0-37049029259-
dc.identifier.volume17-
dc.identifier.issue1-
dc.identifier.spage69-
dc.identifier.epage72-
dc.identifier.isiWOS:000256201400016-

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