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  Patent History
  • Application
    PC T/CN2012080322 2012-08-17
  • Publication
    WO 2013023617 2013-02-21
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Patent: NOVEL BIOACTIVE PROTEIN ISOLATED FRON CHINESE YAM AND USES THEREOF

TitleNOVEL BIOACTIVE PROTEIN ISOLATED FRON CHINESE YAM AND USES THEREOF
Priority Date2011-08-17 US 12/1524477P
Inventors
Issue Date2013
Citation
WO Published patent application WO 2013023617. World Intellectual Property Organization (WIPO), PatentScope, 2013 How to Cite?
AbstractA protein isolated from the Chinese yam Dioscorea opposita that stimulates estrogen and progesterone release in vitro and in vivo but does not stimulate the proliferation of breast and ovarian cancer cells is disclosed. The protein exhibits anti-osteoporotic activity in vivo. Also provided are the procedure for isolation and purification of the protein and the N-terminal amino acid sequence of the protein, as well as therapeutic uses of the polypeptide compound and extracts comprising the polypeptide compound for increasing the level of estradiol, estrogen, and/or progesterone in vivo and/or in vitro, for increasing the expression levels of aromatase and/or follicle-stimulating hormone receptor (FSHR), and for treatment of menopausal syndrome.
Persistent Identifierhttp://hdl.handle.net/10722/195823

 

DC FieldValueLanguage
dc.date.accessioned2014-03-12T09:17:30Z-
dc.date.available2014-03-12T09:17:30Z-
dc.date.issued2013-
dc.identifier.citationWO Published patent application WO 2013023617. World Intellectual Property Organization (WIPO), PatentScope, 2013en_US
dc.identifier.urihttp://hdl.handle.net/10722/195823-
dc.description.abstractA protein isolated from the Chinese yam Dioscorea opposita that stimulates estrogen and progesterone release in vitro and in vivo but does not stimulate the proliferation of breast and ovarian cancer cells is disclosed. The protein exhibits anti-osteoporotic activity in vivo. Also provided are the procedure for isolation and purification of the protein and the N-terminal amino acid sequence of the protein, as well as therapeutic uses of the polypeptide compound and extracts comprising the polypeptide compound for increasing the level of estradiol, estrogen, and/or progesterone in vivo and/or in vitro, for increasing the expression levels of aromatase and/or follicle-stimulating hormone receptor (FSHR), and for treatment of menopausal syndrome.en_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documentsen_US
dc.titleNOVEL BIOACTIVE PROTEIN ISOLATED FRON CHINESE YAM AND USES THEREOFen_US
dc.typePatenten_US
dc.identifier.authoritySZE, CHOWING=rp00514en_US
dc.identifier.authorityTONG, YAO=rp00509en_US
dc.identifier.authorityZHANG, YANBO=rp01410en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorSZE, CHOWINGen_US
dc.contributor.inventorWONG, KAMLOKen_US
dc.contributor.inventorTONG, YAOen_US
dc.contributor.inventorZHANG, YANBOen_US
dc.contributor.inventorCHEUNG, HOPANen_US
patents.identifier.applicationPC T/CN2012080322en_US
patents.description.assigneeUNIV HONG KONG [CN]; SZE CHOWING [CN]; WONG KAMLOK [CN]; TONG YAO [CN]; ZHANG YANBO [CN]; CHEUNG HOPAN [CN]en_US
patents.description.countryWorld Intellectual Property Organization (WIPO)en_US
patents.date.publication2013-02-21en_US
patents.identifier.hkutechidSCM-2011-00393-2-
patents.date.application2012-08-17en_US
patents.date.priority2011-08-17 US 12/1524477Pen_US
patents.description.ccwoen_US
patents.identifier.publicationWO 2013023617en_US
patents.relation.familyUS 2013217626 (A1) 2013-08-22en_US
patents.description.kindA1en_US

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