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- Publisher Website: 10.1042/CS20040168
- Scopus: eid_2-s2.0-10344227673
- PMID: 15333020
- WOS: WOS:000225671000002
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Article: The cellular basis of albuminuria
Title | The cellular basis of albuminuria |
---|---|
Authors | |
Keywords | Albuminuria Basement membrane Endothelial cell Glomerular filtration Nephrotic syndrome Podocyte Proteinuria |
Issue Date | 2004 |
Citation | Clinical Science, 2004, v. 107 n. 6, p. 533-538 How to Cite? |
Abstract | The appearance of albumin in the urine has long been recognized as a cardinal feature of kidney disease and more recently has been shown to also be an independent cardiovascular risk factor associated with insulin resistance. Recent studies on rare human genetic variants, targeted gene disruption in mouse models and cultured glomerular cells in vitro have dramatically improved our understanding of the cellular and molecular basis of albuminuria. This review aims to summarize the current state of knowledge, to illustrate known mechanisms of proteinuria in disease states and to suggest a possible explanation for the link between albuminuria and insulin resistance. |
Persistent Identifier | http://hdl.handle.net/10722/195390 |
ISSN | 2023 Impact Factor: 6.7 2023 SCImago Journal Rankings: 1.565 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Mathieson, PW | - |
dc.date.accessioned | 2014-02-28T06:12:05Z | - |
dc.date.available | 2014-02-28T06:12:05Z | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Clinical Science, 2004, v. 107 n. 6, p. 533-538 | - |
dc.identifier.issn | 0143-5221 | - |
dc.identifier.uri | http://hdl.handle.net/10722/195390 | - |
dc.description.abstract | The appearance of albumin in the urine has long been recognized as a cardinal feature of kidney disease and more recently has been shown to also be an independent cardiovascular risk factor associated with insulin resistance. Recent studies on rare human genetic variants, targeted gene disruption in mouse models and cultured glomerular cells in vitro have dramatically improved our understanding of the cellular and molecular basis of albuminuria. This review aims to summarize the current state of knowledge, to illustrate known mechanisms of proteinuria in disease states and to suggest a possible explanation for the link between albuminuria and insulin resistance. | - |
dc.language | eng | - |
dc.relation.ispartof | Clinical Science | - |
dc.subject | Albuminuria | - |
dc.subject | Basement membrane | - |
dc.subject | Endothelial cell | - |
dc.subject | Glomerular filtration | - |
dc.subject | Nephrotic syndrome | - |
dc.subject | Podocyte | - |
dc.subject | Proteinuria | - |
dc.title | The cellular basis of albuminuria | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1042/CS20040168 | - |
dc.identifier.pmid | 15333020 | - |
dc.identifier.scopus | eid_2-s2.0-10344227673 | - |
dc.identifier.volume | 107 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 533 | - |
dc.identifier.epage | 538 | - |
dc.identifier.isi | WOS:000225671000002 | - |
dc.identifier.issnl | 0143-5221 | - |