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Article: The cellular basis of albuminuria

TitleThe cellular basis of albuminuria
Authors
Issue Date2004
Citation
Clinical Science, 2004, v. 107 n. 6, p. 533-538 How to Cite?
AbstractThe appearance of albumin in the urine has long been recognized as a cardinal feature of kidney disease and more recently has been shown to also be an independent cardiovascular risk factor associated with insulin resistance. Recent studies on rare human genetic variants, targeted gene disruption in mouse models and cultured glomerular cells in vitro have dramatically improved our understanding of the cellular and molecular basis of albuminuria. This review aims to summarize the current state of knowledge, to illustrate known mechanisms of proteinuria in disease states and to suggest a possible explanation for the link between albuminuria and insulin resistance.
Persistent Identifierhttp://hdl.handle.net/10722/195390
ISSN
2015 Impact Factor: 4.996
2015 SCImago Journal Rankings: 2.427

 

DC FieldValueLanguage
dc.contributor.authorMathieson, PW-
dc.date.accessioned2014-02-28T06:12:05Z-
dc.date.available2014-02-28T06:12:05Z-
dc.date.issued2004-
dc.identifier.citationClinical Science, 2004, v. 107 n. 6, p. 533-538-
dc.identifier.issn0143-5221-
dc.identifier.urihttp://hdl.handle.net/10722/195390-
dc.description.abstractThe appearance of albumin in the urine has long been recognized as a cardinal feature of kidney disease and more recently has been shown to also be an independent cardiovascular risk factor associated with insulin resistance. Recent studies on rare human genetic variants, targeted gene disruption in mouse models and cultured glomerular cells in vitro have dramatically improved our understanding of the cellular and molecular basis of albuminuria. This review aims to summarize the current state of knowledge, to illustrate known mechanisms of proteinuria in disease states and to suggest a possible explanation for the link between albuminuria and insulin resistance.-
dc.languageeng-
dc.relation.ispartofClinical Science-
dc.titleThe cellular basis of albuminuria-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1042/CS20040168-
dc.identifier.pmid15333020-
dc.identifier.scopuseid_2-s2.0-10344227673-
dc.identifier.volume107-
dc.identifier.issue6-
dc.identifier.spage533-
dc.identifier.epage538-

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