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Article: Characterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA

TitleCharacterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA
Authors
Issue Date1989
Citation
FEBS Letters, 1989, v. 249 n. 1, p. 35-41 How to Cite?
AbstractSarcoplasmic reticulum Ca2+-ATPase cDNA clones have been isolated from an adult rat heart cDNA library and the nucleotide sequence of the Ca2+-ATPase mRNA determined. The sequence has an open reading frame of 997 codons. It is identical to a cDNA isolated from a rat stomach cDNA library and 90% isologous to the rabbit and human slow/ cardiac cDNAs. Nuclease S1 mapping analysis indicates that this sequence corresponds to the main Ca2+-ATPase mRNA present in heart and in slow skeletal muscle and that it is expressed in various proportions in smooth and non-muscle tissues, together with another isoform which differs from the cardiac form in the sequence of its 3′-end. © 1989.
Persistent Identifierhttp://hdl.handle.net/10722/195218
ISSN
2015 Impact Factor: 3.519
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ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLompre, A-M-
dc.contributor.authorde la Bastie, D-
dc.contributor.authorBoheler, KR-
dc.contributor.authorSchwartz, K-
dc.date.accessioned2014-02-25T01:40:19Z-
dc.date.available2014-02-25T01:40:19Z-
dc.date.issued1989-
dc.identifier.citationFEBS Letters, 1989, v. 249 n. 1, p. 35-41-
dc.identifier.issn0014-5793-
dc.identifier.urihttp://hdl.handle.net/10722/195218-
dc.description.abstractSarcoplasmic reticulum Ca2+-ATPase cDNA clones have been isolated from an adult rat heart cDNA library and the nucleotide sequence of the Ca2+-ATPase mRNA determined. The sequence has an open reading frame of 997 codons. It is identical to a cDNA isolated from a rat stomach cDNA library and 90% isologous to the rabbit and human slow/ cardiac cDNAs. Nuclease S1 mapping analysis indicates that this sequence corresponds to the main Ca2+-ATPase mRNA present in heart and in slow skeletal muscle and that it is expressed in various proportions in smooth and non-muscle tissues, together with another isoform which differs from the cardiac form in the sequence of its 3′-end. © 1989.-
dc.languageeng-
dc.relation.ispartofFEBS Letters-
dc.titleCharacterization and expression of the rat heart sarcoplasmic reticulum Ca2+-ATPase mRNA-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/0014-5793(89)80010-9-
dc.identifier.pmid2542094-
dc.identifier.scopuseid_2-s2.0-0024389481-
dc.identifier.volume249-
dc.identifier.issue1-
dc.identifier.spage35-
dc.identifier.epage41-
dc.identifier.isiWOS:A1989U895900009-

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