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Article: Detection of glaucoma in a cohort of chinese subjects with systemic hypertension

TitleDetection of glaucoma in a cohort of chinese subjects with systemic hypertension
Authors
Issue Date2013
Citation
Journal of Ophthalmology, 2013, v. 2013, article no. 463710 How to Cite?
AbstractPurpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with IOP > 21 mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). Results. The mean age of the subjects was 64.66 ± 9.47 years, and the male:female ratio was 92: 108. All patients were hypertensive with a mean blood pressure (BP) of 131.1 ± 15.1 / 76.6 ± 11.1 mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. Conclusion. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type. © 2013 Rita A. Gangwani et al.
Persistent Identifierhttp://hdl.handle.net/10722/195146
ISSN
2015 Impact Factor: 1.463
2015 SCImago Journal Rankings: 0.870
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorGangwani, RA-
dc.contributor.authorChan, J-
dc.contributor.authorLee, J-
dc.contributor.authorKwong, A-
dc.contributor.authorLai, JSM-
dc.date.accessioned2014-02-25T01:40:14Z-
dc.date.available2014-02-25T01:40:14Z-
dc.date.issued2013-
dc.identifier.citationJournal of Ophthalmology, 2013, v. 2013, article no. 463710-
dc.identifier.issn2090-004X-
dc.identifier.urihttp://hdl.handle.net/10722/195146-
dc.description.abstractPurpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via frequency doubling technology (FDT) perimetry and intraocular pressure (IOP) measurement by noncontact tonometry (NCT) in a general outpatient clinic. Those with IOP > 21 mmHg and/or visual field (VF) defects on FDT were referred for complete ophthalmological examination. The diagnosis of glaucoma was based on an abnormal VF on Humphrey Field Analyzer (HFA) by Hodapp-Parrish-Anderson's criteria and an increased vertical cup-disc ratio (VCDR). Results. The mean age of the subjects was 64.66 ± 9.47 years, and the male:female ratio was 92: 108. All patients were hypertensive with a mean blood pressure (BP) of 131.1 ± 15.1 / 76.6 ± 11.1 mmHg whilst on systemic antihypertensive medication. Of the 111 patients that had an abnormal initial screening, 14 (7.9%) were confirmed to have glaucoma with the highest prevalence of normal tension glaucoma (NTG) (6.2%), followed by primary angle closure glaucoma (PACG) (1.1%) and primary open angle glaucoma (POAG) (0.5%). The positive predictive value of FDT perimetry was 71%. Conclusion. Nearly 8% of the adults with systemic hypertension had glaucoma, and NTG was the most prevalent type. © 2013 Rita A. Gangwani et al.-
dc.languageeng-
dc.relation.ispartofJournal of Ophthalmology-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleDetection of glaucoma in a cohort of chinese subjects with systemic hypertension-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2013/463710-
dc.identifier.pmcidPMC3557632-
dc.identifier.scopuseid_2-s2.0-84884270707-
dc.identifier.hkuros224910-
dc.identifier.volume2013-
dc.identifier.spagearticle no. 463710-
dc.identifier.epagearticle no. 463710-
dc.identifier.isiWOS:000314128600001-

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