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Article: E-cadherin in gastric cancer

TitleE-cadherin in gastric cancer
Authors
Issue Date2006
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm
Citation
World Journal of Gastroenterology, 2006, v. 12 n. 2, p. 199-203 How to Cite?
AbstractCadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cadherin is the prototype of the class E-cadherin that links to catenins to form the cytoskeleton. Recent evidence has shown that E-cadherin not only acts as an adhesive, but also plays important roles in growth development and carcinogenesis. It has been recently viewed as an invasion as well as a growth suppressor gene. This review summarizes the recent discoveries on E-cadherin and its role in gastric cancer. In particular, our work on E-cadherin in gastric cancer, including its relation with Helicobacter pylori and clinical applications, are described in detail.
Persistent Identifierhttp://hdl.handle.net/10722/194550
ISSN
2015 Impact Factor: 2.787
2015 SCImago Journal Rankings: 1.076
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, AOO-
dc.date.accessioned2014-02-11T07:57:30Z-
dc.date.available2014-02-11T07:57:30Z-
dc.date.issued2006-
dc.identifier.citationWorld Journal of Gastroenterology, 2006, v. 12 n. 2, p. 199-203-
dc.identifier.issn1007-9327-
dc.identifier.urihttp://hdl.handle.net/10722/194550-
dc.description.abstractCadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cadherin is the prototype of the class E-cadherin that links to catenins to form the cytoskeleton. Recent evidence has shown that E-cadherin not only acts as an adhesive, but also plays important roles in growth development and carcinogenesis. It has been recently viewed as an invasion as well as a growth suppressor gene. This review summarizes the recent discoveries on E-cadherin and its role in gastric cancer. In particular, our work on E-cadherin in gastric cancer, including its relation with Helicobacter pylori and clinical applications, are described in detail.-
dc.languageeng-
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm-
dc.relation.ispartofWorld Journal of Gastroenterology-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshCadherins - analysis - genetics - physiology-
dc.subject.meshGenes, Tumor Suppressor-
dc.subject.meshHelicobacter Infections - complications-
dc.subject.meshHelicobacter pylori-
dc.subject.meshStomach Neoplasms - etiology - genetics-
dc.titleE-cadherin in gastric canceren_US
dc.typeArticleen_US
dc.identifier.emailChan, AOO: aoochan@hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3748/wjg.v12.i2.199-
dc.identifier.pmid16482618-
dc.identifier.pmcidPMC4066027-
dc.identifier.hkuros122750-
dc.identifier.volume12-
dc.identifier.issue2-
dc.identifier.spage199-
dc.identifier.epage203-
dc.identifier.isiWOS:000239946500004-
dc.publisher.placeUnited States-

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