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Article: Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage

TitleAntiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage
Authors
Issue Date2013
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.mrw.interscience.wiley.com/cochrane/cochrane_clsysrev_articles_fs.html
Citation
Cochrane Database of Systematic Reviews (Online), 2013, v. 6, p. CD008710 How to Cite?
AbstractBACKGROUND: Subarachnoid haemorrhage may result in seizures both acutely and in the longer term. The use of antiepileptic drugs (AEDs) in the primary and secondary prevention of seizures after subarachnoid haemorrhage is uncertain, and there is currently no consensus on treatment. OBJECTIVES: To assess the effects of AEDs for the primary and secondary prevention of seizures after subarachnoid haemorrhage. SEARCH METHODS: We searched the Cochrane Epilepsy Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (2013, Issue 1) in The Cochrane Library, and MEDLINE (1946 to 12th March 2013). We checked the reference lists of articles retrieved from these searches. SELECTION CRITERIA: We considered all randomised and quasi-randomised controlled trials in which patients were assigned to a treatment (one or more AEDs) or placebo. DATA COLLECTION AND ANALYSIS: Two review authors (RM and JK) independently screened and assessed the methodological quality of the studies. If studies were included, one author extracted the data and the other checked it. MAIN RESULTS: No relevant studies were found. AUTHORS' CONCLUSIONS: There was no evidence to support or refute the use of antiepileptic drugs for the primary or secondary prevention of seizures related to subarachnoid haemorrhage. Well-designed randomised controlled trials are urgently needed to guide clinical practice.
Persistent Identifierhttp://hdl.handle.net/10722/194540
ISSN
2014 Impact Factor: 6.035
2015 SCImago Journal Rankings: 2.366
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMarigold, R-
dc.contributor.authorGunther, A-
dc.contributor.authorTiwari, D-
dc.contributor.authorKwan, SKJ-
dc.date.accessioned2014-02-07T02:23:53Z-
dc.date.available2014-02-07T02:23:53Z-
dc.date.issued2013-
dc.identifier.citationCochrane Database of Systematic Reviews (Online), 2013, v. 6, p. CD008710-
dc.identifier.issn1469-493X-
dc.identifier.urihttp://hdl.handle.net/10722/194540-
dc.description.abstractBACKGROUND: Subarachnoid haemorrhage may result in seizures both acutely and in the longer term. The use of antiepileptic drugs (AEDs) in the primary and secondary prevention of seizures after subarachnoid haemorrhage is uncertain, and there is currently no consensus on treatment. OBJECTIVES: To assess the effects of AEDs for the primary and secondary prevention of seizures after subarachnoid haemorrhage. SEARCH METHODS: We searched the Cochrane Epilepsy Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (2013, Issue 1) in The Cochrane Library, and MEDLINE (1946 to 12th March 2013). We checked the reference lists of articles retrieved from these searches. SELECTION CRITERIA: We considered all randomised and quasi-randomised controlled trials in which patients were assigned to a treatment (one or more AEDs) or placebo. DATA COLLECTION AND ANALYSIS: Two review authors (RM and JK) independently screened and assessed the methodological quality of the studies. If studies were included, one author extracted the data and the other checked it. MAIN RESULTS: No relevant studies were found. AUTHORS' CONCLUSIONS: There was no evidence to support or refute the use of antiepileptic drugs for the primary or secondary prevention of seizures related to subarachnoid haemorrhage. Well-designed randomised controlled trials are urgently needed to guide clinical practice.-
dc.languageeng-
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.mrw.interscience.wiley.com/cochrane/cochrane_clsysrev_articles_fs.html-
dc.relation.ispartofCochrane Database of Systematic Reviews (Online)-
dc.rightsCochrane Database of Systematic Reviews (Online). Copyright © John Wiley & Sons Ltd.-
dc.rightsThis review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2013, Issue 6, Art. No.: CD008710. DOI: 10.1002/14651858.CD008710.pub2. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshAnticonvulsants - therapeutic use-
dc.subject.meshHumans-
dc.subject.meshSecondary Prevention - methods-
dc.subject.meshSeizures - etiology - prevention and control-
dc.subject.meshSubarachnoid Hemorrhage - complications-
dc.titleAntiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhageen_US
dc.typeArticleen_US
dc.identifier.emailKwan, SKJ: jskkwan@hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1002/14651858.CD008710.pub2-
dc.identifier.pmid23740537-
dc.identifier.hkuros227906-
dc.identifier.volume6-
dc.identifier.spageCD008710-
dc.identifier.epageCD008710-
dc.identifier.isiWOS:000321124500038-
dc.publisher.placeUnited Kingdom-

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