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Article: Gestational diabetes mellitus and neonatal hyperthyrotropinemia

TitleGestational diabetes mellitus and neonatal hyperthyrotropinemia
Authors
Issue Date2002
Citation
Gynecologic and Obstetric Investigation, 2002, v. 53 n. 3, p. 135-139 How to Cite?
AbstractObjective: To determine whether gestational diabetes mellitus (GDM) is associated with increased incidence of neonatal hyperthyrotropinemia. Study Design: In a retrospective study, maternal characteristics, infant outcome and cord blood thyrotropin (TSH) concentration were compared between 469 diet-treated GDM pregnancies diagnosed by the World Health Organization 75 g oral glucose tolerance test (OGTT) with 474 non-diabetic pregnancies with normal OGTT results. Results: Hyperthyrotropinemia (TSH > 16 mIU/l) was found in 7.2% of the GDM pregnancies and 2.1% of the controls (p < 0.001), but there was no difference in the birth weight or gestational age. The TSH concentration was correlated with the OGTT 2-hour glucose value (p = 0.0948, p = 0.029) and Apgar score at the fifth minute (p = -0.1197, p = 0.009). There was no difference in the TSH or free thyroxine concentrations between the hyperthyrotropinemic newborns of the GDM and control groups. In the GDM group, the hyperthyrotropinemic newborns had a higher incidence (p = 0.017) of neonatal jaundice. Conclusions: Neonatal hyperthyrotropinemia is more frequently found in pregnancies with GDM, and this could have reflected increased fetal in-utero hypoxic stress in these pregnancies. Copyright © 2002 S. Karger AG, Basel.
Persistent Identifierhttp://hdl.handle.net/10722/194127
ISSN
2015 Impact Factor: 1.672
2015 SCImago Journal Rankings: 0.752
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLao, TT-
dc.contributor.authorLee, C-P-
dc.date.accessioned2014-01-30T03:32:12Z-
dc.date.available2014-01-30T03:32:12Z-
dc.date.issued2002-
dc.identifier.citationGynecologic and Obstetric Investigation, 2002, v. 53 n. 3, p. 135-139-
dc.identifier.issn0378-7346-
dc.identifier.urihttp://hdl.handle.net/10722/194127-
dc.description.abstractObjective: To determine whether gestational diabetes mellitus (GDM) is associated with increased incidence of neonatal hyperthyrotropinemia. Study Design: In a retrospective study, maternal characteristics, infant outcome and cord blood thyrotropin (TSH) concentration were compared between 469 diet-treated GDM pregnancies diagnosed by the World Health Organization 75 g oral glucose tolerance test (OGTT) with 474 non-diabetic pregnancies with normal OGTT results. Results: Hyperthyrotropinemia (TSH > 16 mIU/l) was found in 7.2% of the GDM pregnancies and 2.1% of the controls (p < 0.001), but there was no difference in the birth weight or gestational age. The TSH concentration was correlated with the OGTT 2-hour glucose value (p = 0.0948, p = 0.029) and Apgar score at the fifth minute (p = -0.1197, p = 0.009). There was no difference in the TSH or free thyroxine concentrations between the hyperthyrotropinemic newborns of the GDM and control groups. In the GDM group, the hyperthyrotropinemic newborns had a higher incidence (p = 0.017) of neonatal jaundice. Conclusions: Neonatal hyperthyrotropinemia is more frequently found in pregnancies with GDM, and this could have reflected increased fetal in-utero hypoxic stress in these pregnancies. Copyright © 2002 S. Karger AG, Basel.-
dc.languageeng-
dc.relation.ispartofGynecologic and Obstetric Investigation-
dc.titleGestational diabetes mellitus and neonatal hyperthyrotropinemia-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1159/000058363-
dc.identifier.pmid12053096-
dc.identifier.scopuseid_2-s2.0-0036284669-
dc.identifier.volume53-
dc.identifier.issue3-
dc.identifier.spage135-
dc.identifier.epage139-
dc.identifier.isiWOS:000176409800001-

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