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Patent History
- ApplicationUS 12/508913 2009-07-24
- GrantedUS 20090291493 2009-11-26
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granted patent: HUMAN IMMUNODEFICIENCY VIRUS-NEUTRALIZING ANTIBODIES WITH IMPROVED BREADTH AND POTENCY
Title | HUMAN IMMUNODEFICIENCY VIRUS-NEUTRALIZING ANTIBODIES WITH IMPROVED BREADTH AND POTENCY |
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Granted Patent | US 20090291493 |
Granted Date | 2009-11-26 |
Priority Date | 2009-07-24 US 12/508913 2004-12-15 US 10/512966 2003-05-06 PCT/US2003014095 2002-05-06 US 10/378406P |
Inventors | |
Issue Date | 2009 |
Citation | US Patent US 20090291493. Washington, DC: US Patent and Trademark Office (USPTO), 2009 How to Cite? |
Abstract | The present invention provides an antibody to human immunodeficiency virus (HIV) envelope glycoprotein that can recognize one or more strains of HIV, wherein the epitope of HIV recognized by the antibody is inducible, and wherein the antibody binding to the epitope is enhanced by the presence of CD4 and the HIV co-receptor, and related fusion proteins, conjugates, nucleic acids, vectors, host cells, compositions and methods of use to inhibit an infection of a human at risk of becoming infected with HIV, to reduce the severity of an infection of a human infected with HIV, and to treat an infection of a human with HIV. |
Persistent Identifier | http://hdl.handle.net/10722/194059 |
DC Field | Value | Language |
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dc.date.accessioned | 2014-01-29T05:23:45Z | - |
dc.date.available | 2014-01-29T05:23:45Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | US Patent US 20090291493. Washington, DC: US Patent and Trademark Office (USPTO), 2009 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/194059 | - |
dc.description.abstract | The present invention provides an antibody to human immunodeficiency virus (HIV) envelope glycoprotein that can recognize one or more strains of HIV, wherein the epitope of HIV recognized by the antibody is inducible, and wherein the antibody binding to the epitope is enhanced by the presence of CD4 and the HIV co-receptor, and related fusion proteins, conjugates, nucleic acids, vectors, host cells, compositions and methods of use to inhibit an infection of a human at risk of becoming infected with HIV, to reduce the severity of an infection of a human infected with HIV, and to treat an infection of a human with HIV. | en_US |
dc.title | HUMAN IMMUNODEFICIENCY VIRUS-NEUTRALIZING ANTIBODIES WITH IMPROVED BREADTH AND POTENCY | en_US |
dc.type | Patent | en_US |
dc.description.nature | published_or_final_version | - |
dc.contributor.inventor | DIMTROV DIMITER S | en_US |
dc.contributor.inventor | ZHANG MEI-YUN | en_US |
patents.identifier.application | US 12/508913 | en_US |
patents.identifier.granted | US 20090291493 | en_US |
patents.description.assignee | US HEALTH [US] | en_US |
patents.description.country | United States of America | en_US |
patents.date.granted | 2009-11-26 | en_US |
patents.date.application | 2009-07-24 | en_US |
patents.date.priority | 2009-07-24 US 12/508913 | en_US |
patents.date.priority | 2004-12-15 US 10/512966 | en_US |
patents.date.priority | 2003-05-06 PCT/US2003014095 | en_US |
patents.date.priority | 2002-05-06 US 10/378406P | en_US |
patents.description.cc | us | en_US |
patents.relation.family | AU 2003239356 (A1) 2003-11-11 | en_US |
patents.relation.family | CA 2485120 (A1) 2003-11-20 | en_US |
patents.relation.family | EP 1504034 (A1) 2005-02-09 | en_US |
patents.relation.family | US 2005164166 (A1) 2005-07-28 | en_US |
patents.relation.family | US 7566451 (B2) 2009-07-28 | en_US |
patents.relation.family | US 8110192 (B2) 2012-02-07 | en_US |
patents.relation.family | WO 03095492 (A1) 2003-11-20 | en_US |
patents.description.kind | A1 | en_US |
patents.type | Patent_granted | en_US |