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Article: A study on the mutagenic effect of dichloromethane extract of pickled vegetables from high risk area for nasopharyngeal carcinoma (NPC)-in Sihui County

TitleA study on the mutagenic effect of dichloromethane extract of pickled vegetables from high risk area for nasopharyngeal carcinoma (NPC)-in Sihui County
鼻咽癌高發區四會縣醃菜二氯甲烷提取液的誘變性研究
Authors
Keywords誘變性
二氯甲烷提取
四會縣
小鼠骨髓細胞
動物實驗
Issue Date1990
PublisherSun Yat-sen University Cancer Center (中山醫科大學腫瘤防治中心). The Journal's web site is located at http://www.cjcsysu.cn/
Citation
Chinese Journal of Cancer, 1990, v. 9 n. 1, p. 22-24 How to Cite?
癌症, 1990, v. 9 n. 1, p. 22-24 How to Cite?
AbstractThe mutagenic effect of dichloromethane extract of pickles collected from Sinhui County was examined. Sample I markedly increased the frequency of sister chromatid exchange (SCE) and the rate of micronucleus (MN) in mice. Sample II also induced an increase in SCE frequency significantly, but the increase in MN rate was slight. Chemical analyses showed that two samples of pickles contained 37.83ppb and 33.38ppb of volatile nitrosamines, respectively, which alone could not explain the observed mutagenic effect. These results sug ested that the pickled vegetables taken from NPC high-risk area, Sihui County, may contain some mutagen(s) besides volatile nitrosamines. 本文報告四會縣醃菜二氯甲烷提取液的誘變性試驗。醃菜樣本提取液Ⅰ號引起姐妹染色單體交換(SCE)率及微核(MN)率顯著升高,醃菜樣本提取液Ⅱ號亦引起SCE率明顯升高,但MN率僅略有升高。化學分析表明,該兩份醃菜的揮發性亞硝胺含量分別為37.83、33.38 ppb。醃菜提取液的誘變性似不能單用亞硝胺來解釋。實驗結果提示,鼻咽癌高發區四會縣醃菜中可能含有除揮發性亞硝胺以外的其他誘變性物質。
Persistent Identifierhttp://hdl.handle.net/10722/194038
ISSN
2015 Impact Factor: 2.814
2015 SCImago Journal Rankings: 1.081

 

DC FieldValueLanguage
dc.contributor.authorHuang, JCen_US
dc.contributor.authorLong, JBen_US
dc.contributor.authorYang, RPen_US
dc.contributor.authorRuan, HYen_US
dc.contributor.authorFeng, GKen_US
dc.contributor.authorCheng, Yen_US
dc.contributor.authorKuang, ZJen_US
dc.contributor.authorMei, CEen_US
dc.date.accessioned2014-01-28T08:19:06Z-
dc.date.available2014-01-28T08:19:06Z-
dc.date.issued1990en_US
dc.identifier.citationChinese Journal of Cancer, 1990, v. 9 n. 1, p. 22-24en_US
dc.identifier.citation癌症, 1990, v. 9 n. 1, p. 22-24-
dc.identifier.issn1000-467X-
dc.identifier.urihttp://hdl.handle.net/10722/194038-
dc.description.abstractThe mutagenic effect of dichloromethane extract of pickles collected from Sinhui County was examined. Sample I markedly increased the frequency of sister chromatid exchange (SCE) and the rate of micronucleus (MN) in mice. Sample II also induced an increase in SCE frequency significantly, but the increase in MN rate was slight. Chemical analyses showed that two samples of pickles contained 37.83ppb and 33.38ppb of volatile nitrosamines, respectively, which alone could not explain the observed mutagenic effect. These results sug ested that the pickled vegetables taken from NPC high-risk area, Sihui County, may contain some mutagen(s) besides volatile nitrosamines. 本文報告四會縣醃菜二氯甲烷提取液的誘變性試驗。醃菜樣本提取液Ⅰ號引起姐妹染色單體交換(SCE)率及微核(MN)率顯著升高,醃菜樣本提取液Ⅱ號亦引起SCE率明顯升高,但MN率僅略有升高。化學分析表明,該兩份醃菜的揮發性亞硝胺含量分別為37.83、33.38 ppb。醃菜提取液的誘變性似不能單用亞硝胺來解釋。實驗結果提示,鼻咽癌高發區四會縣醃菜中可能含有除揮發性亞硝胺以外的其他誘變性物質。-
dc.languagechien_US
dc.publisherSun Yat-sen University Cancer Center (中山醫科大學腫瘤防治中心). The Journal's web site is located at http://www.cjcsysu.cn/-
dc.relation.ispartofChinese Journal of Canceren_US
dc.relation.ispartof癌症-
dc.subject誘變性-
dc.subject二氯甲烷提取-
dc.subject四會縣-
dc.subject小鼠骨髓細胞-
dc.subject動物實驗-
dc.titleA study on the mutagenic effect of dichloromethane extract of pickled vegetables from high risk area for nasopharyngeal carcinoma (NPC)-in Sihui Countyen_US
dc.title鼻咽癌高發區四會縣醃菜二氯甲烷提取液的誘變性研究-
dc.typeArticleen_US
dc.identifier.emailCheng, Y: yuecheng@hku.hken_US
dc.identifier.authorityCheng, Y=rp01320en_US
dc.identifier.volume9en_US
dc.identifier.issue1-
dc.identifier.spage22en_US
dc.identifier.epage24en_US
dc.publisher.placeChina (中國)-

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