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Conference Paper: Outcome of local Chinese men undergoing primary androgen deprivation therapy for prostate cancer

TitleOutcome of local Chinese men undergoing primary androgen deprivation therapy for prostate cancer
Authors
Issue Date2014
PublisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/
Citation
Hong Kong Urological Association Annual Scientific Meeting, Hong Kong, 10 November 2013. In BJU International, 2014, v. 113 n. Suppl. S1, p. 9 How to Cite?
AbstractObjective: To evaluate and analyze the outcome of patients with prostate cancer treated with primary androgen deprivation therapy. Patients & Method: Patients with prostate cancer treated with primary androgen deprivation therapy in Queen Mary Hospital from 2001 to 2011 were reviewed. Survival outcome and predictive factors of survival were evaluated with Kaplan-Meier and Cox regression analyses. Results: A total of 281 patients were included with a mean follow up of 31.5 ± 23.4 months. The 5-year overall and cancer-specific survival rates were 41% and 65% respectively. Gleason score, presence of bone metastases, clinical stage, baseline PSA, PSA nadir and time to PSA nadir were significant predictor factors of overall and cancer-specific survival upon Kaplan-Meier analysis. PSA nadir (p < 0.001, 95% CI 1.007–1.019) and time to PSA nadir (p = 0.007, 95% CI 0.886–0.981) were the only two significant predictive factors of cancer-specific survival upon Cox regression analysis. For patients of any PSA nadir subgroup, time to PSA nadir remained as a significant predictor of both overall and cancer-specific survival. Conclusion: In local Chinese men with advanced or metastatic prostate cancer receiving primary androgen deprivation therapy, their PSA nadir and time to PSA nadir were significant factors affecting cancer-specific survival upon multivariate analysis.
DescriptionOral Presentation
Persistent Identifierhttp://hdl.handle.net/10722/193964
ISSN
2015 Impact Factor: 4.387
2015 SCImago Journal Rankings: 2.009

 

DC FieldValueLanguage
dc.contributor.authorTeoh, JYen_US
dc.contributor.authorWong, KWen_US
dc.contributor.authorTsu, HLJen_US
dc.contributor.authorNg, ATLen_US
dc.contributor.authorWong, EMHen_US
dc.contributor.authorHo, KLen_US
dc.contributor.authorYiu, MKen_US
dc.date.accessioned2014-01-28T06:38:22Z-
dc.date.available2014-01-28T06:38:22Z-
dc.date.issued2014en_US
dc.identifier.citationHong Kong Urological Association Annual Scientific Meeting, Hong Kong, 10 November 2013. In BJU International, 2014, v. 113 n. Suppl. S1, p. 9en_US
dc.identifier.issn1464-4096-
dc.identifier.urihttp://hdl.handle.net/10722/193964-
dc.descriptionOral Presentation-
dc.description.abstractObjective: To evaluate and analyze the outcome of patients with prostate cancer treated with primary androgen deprivation therapy. Patients & Method: Patients with prostate cancer treated with primary androgen deprivation therapy in Queen Mary Hospital from 2001 to 2011 were reviewed. Survival outcome and predictive factors of survival were evaluated with Kaplan-Meier and Cox regression analyses. Results: A total of 281 patients were included with a mean follow up of 31.5 ± 23.4 months. The 5-year overall and cancer-specific survival rates were 41% and 65% respectively. Gleason score, presence of bone metastases, clinical stage, baseline PSA, PSA nadir and time to PSA nadir were significant predictor factors of overall and cancer-specific survival upon Kaplan-Meier analysis. PSA nadir (p < 0.001, 95% CI 1.007–1.019) and time to PSA nadir (p = 0.007, 95% CI 0.886–0.981) were the only two significant predictive factors of cancer-specific survival upon Cox regression analysis. For patients of any PSA nadir subgroup, time to PSA nadir remained as a significant predictor of both overall and cancer-specific survival. Conclusion: In local Chinese men with advanced or metastatic prostate cancer receiving primary androgen deprivation therapy, their PSA nadir and time to PSA nadir were significant factors affecting cancer-specific survival upon multivariate analysis.-
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/-
dc.relation.ispartofBJU Internationalen_US
dc.rightsThe definitive version is available at www3.interscience.wiley.com-
dc.titleOutcome of local Chinese men undergoing primary androgen deprivation therapy for prostate canceren_US
dc.typeConference_Paperen_US
dc.identifier.emailTsu, HLJ: jamestsu@hku.hken_US
dc.identifier.emailHo, KL: hkl218@hkucc.hku.hken_US
dc.identifier.emailYiu, MK: pmkyiu@hku.hken_US
dc.identifier.doi10.1111/bju.12606-
dc.identifier.hkuros227504en_US
dc.identifier.volume113-
dc.identifier.issueSuppl. S1-
dc.identifier.spage9-
dc.identifier.epage9-
dc.publisher.placeUnited Kingdom-

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