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Conference Paper: Pathological outcomes of Hong Kong Chinese patients with low risk prostate cancer eligible for active surveillance undergoing radical prostatectomy: comparison of six different protocols
Title | Pathological outcomes of Hong Kong Chinese patients with low risk prostate cancer eligible for active surveillance undergoing radical prostatectomy: comparison of six different protocols |
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Authors | |
Issue Date | 2014 |
Publisher | Wiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/ |
Citation | Hong Kong Urological Association Annual Scientific Meeting, Hong Kong, 10 November 2013. In BJU International, 2014, v. 113 n. Suppl. S1, p. 9 How to Cite? |
Abstract | Objective: To study the outcomes of local Chinese patients eligible for active surveillance (AS) undergoing radical prostatectomy using different AS protocols.
Patients & Methods: From 1998 to 2012, 287 patients underwent radical prostatectomy for prostate cancer. Their pathological data were reviewed. Six different AS protocols were applied to the cohort with patients stratified in six different manners. Comparative analyses of the probabilities of missing unfavorable pathological outcomes were compared.
Results: Extracapsular extension, seminal vesicle invasion, pathological T3 disease and upgrade of Gleason's score were present in 3.3%–17.2%, 1.6–3.4%, 3.3–19.2% and 20.6–34.5% respectively in the protocols. Protocol that considers PSA and Gleason score only had significantly higher rates of missing extracapsular extension and upgrading of pathological T stage.
Conclusion: AS protocol based on PSA and Gleason's score alone may miss higher risk disease. Before widespread use of the various AS protocols, careful analysis of their performance in the local population is advised to minimize rate of missing unfavorable diseases. |
Description | Oral Presentation |
Persistent Identifier | http://hdl.handle.net/10722/193963 |
ISSN | 2023 Impact Factor: 3.7 2023 SCImago Journal Rankings: 1.337 |
DC Field | Value | Language |
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dc.contributor.author | Tsang, CF | en_US |
dc.contributor.author | Tsu, HLJ | en_US |
dc.contributor.author | Ng, ATL | en_US |
dc.contributor.author | Wong, EMH | en_US |
dc.contributor.author | Ho, KL | en_US |
dc.contributor.author | Yiu, MK | en_US |
dc.date.accessioned | 2014-01-28T06:38:22Z | - |
dc.date.available | 2014-01-28T06:38:22Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | Hong Kong Urological Association Annual Scientific Meeting, Hong Kong, 10 November 2013. In BJU International, 2014, v. 113 n. Suppl. S1, p. 9 | en_US |
dc.identifier.issn | 1464-4096 | - |
dc.identifier.uri | http://hdl.handle.net/10722/193963 | - |
dc.description | Oral Presentation | - |
dc.description.abstract | Objective: To study the outcomes of local Chinese patients eligible for active surveillance (AS) undergoing radical prostatectomy using different AS protocols. Patients & Methods: From 1998 to 2012, 287 patients underwent radical prostatectomy for prostate cancer. Their pathological data were reviewed. Six different AS protocols were applied to the cohort with patients stratified in six different manners. Comparative analyses of the probabilities of missing unfavorable pathological outcomes were compared. Results: Extracapsular extension, seminal vesicle invasion, pathological T3 disease and upgrade of Gleason's score were present in 3.3%–17.2%, 1.6–3.4%, 3.3–19.2% and 20.6–34.5% respectively in the protocols. Protocol that considers PSA and Gleason score only had significantly higher rates of missing extracapsular extension and upgrading of pathological T stage. Conclusion: AS protocol based on PSA and Gleason's score alone may miss higher risk disease. Before widespread use of the various AS protocols, careful analysis of their performance in the local population is advised to minimize rate of missing unfavorable diseases. | - |
dc.language | eng | en_US |
dc.publisher | Wiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/ | - |
dc.relation.ispartof | BJU International | en_US |
dc.rights | The definitive version is available at www3.interscience.wiley.com | - |
dc.title | Pathological outcomes of Hong Kong Chinese patients with low risk prostate cancer eligible for active surveillance undergoing radical prostatectomy: comparison of six different protocols | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Tsu, HLJ: jamestsu@hku.hk | en_US |
dc.identifier.email | Ho, KL: hkl218@hkucc.hku.hk | en_US |
dc.identifier.email | Yiu, MK: pmkyiu@hku.hk | en_US |
dc.identifier.doi | 10.1111/bju.12606 | - |
dc.identifier.hkuros | 227503 | en_US |
dc.identifier.volume | 113 | - |
dc.identifier.issue | Suppl. S1 | - |
dc.identifier.spage | 9 | - |
dc.identifier.epage | 9 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1464-4096 | - |