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Conference Paper: Morphometric analysis of the retina in a triple-transgenic model of Alzheimer's disease

TitleMorphometric analysis of the retina in a triple-transgenic model of Alzheimer's disease
Authors
KeywordsMedical sciences
Psychiatry and neurology gerontology and geriatrics
Issue Date2013
PublisherElsevier Inc. The Journal's web site is located at http://www.alzheimersanddementia.org/
Citation
The 2013 International Conference of the Alzheimer’s Association (AAIC), Boston, MA., 13-18 July 2013. In Alzheimer's & Dementia, 2013, v. 9 n. 4 suppl., p. P435 How to Cite?
AbstractBACKGROUND: Reduction of retinal thickness has been reported in patients with mild cognitive impairment and Alzheimer's disease (AD). Recent studies reported Aβ accumulation, increase of TUNEL positive apoptotic bodies in the retinal ganglion cell (RGC) layer. However, morphometric analysis of RGC number and thickness of inner nuclear layer (INL) has not been characterized. We hypothesize that these two parameters can be served as biomarker to monitor degeneration in the retina of AD pathogenesis. Therefore, we aim to examine these two parameters in the retina of triple transgenic (3xTg) mic…
DescriptionThis journal suppl. contain abstracts of AAIC2013
Persistent Identifierhttp://hdl.handle.net/10722/193277
ISSN
2015 Impact Factor: 11.619
2015 SCImago Journal Rankings: 4.289

 

DC FieldValueLanguage
dc.contributor.authorChiu, Ken_US
dc.contributor.authorLeung, SMCen_US
dc.contributor.authorLeung, IYPen_US
dc.contributor.authorLok, CKMen_US
dc.contributor.authorTurner, Ren_US
dc.contributor.authorMatsuoka, Yen_US
dc.contributor.authorSo, KFen_US
dc.contributor.authorChang, RCCen_US
dc.date.accessioned2013-12-20T02:42:23Z-
dc.date.available2013-12-20T02:42:23Z-
dc.date.issued2013en_US
dc.identifier.citationThe 2013 International Conference of the Alzheimer’s Association (AAIC), Boston, MA., 13-18 July 2013. In Alzheimer's & Dementia, 2013, v. 9 n. 4 suppl., p. P435en_US
dc.identifier.issn1552-5260-
dc.identifier.urihttp://hdl.handle.net/10722/193277-
dc.descriptionThis journal suppl. contain abstracts of AAIC2013-
dc.description.abstractBACKGROUND: Reduction of retinal thickness has been reported in patients with mild cognitive impairment and Alzheimer's disease (AD). Recent studies reported Aβ accumulation, increase of TUNEL positive apoptotic bodies in the retinal ganglion cell (RGC) layer. However, morphometric analysis of RGC number and thickness of inner nuclear layer (INL) has not been characterized. We hypothesize that these two parameters can be served as biomarker to monitor degeneration in the retina of AD pathogenesis. Therefore, we aim to examine these two parameters in the retina of triple transgenic (3xTg) mic…-
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.alzheimersanddementia.org/-
dc.relation.ispartofAlzheimer's & Dementiaen_US
dc.subjectMedical sciences-
dc.subjectPsychiatry and neurology gerontology and geriatrics-
dc.titleMorphometric analysis of the retina in a triple-transgenic model of Alzheimer's diseaseen_US
dc.typeConference_Paperen_US
dc.identifier.emailChiu, K: datwai@hkucc.hku.hken_US
dc.identifier.emailLeung, SMC: saracml@hku.hken_US
dc.identifier.emailLok, CKM: kmlok@hku.hken_US
dc.identifier.emailSo, KF: hrmaskf@hku.hken_US
dc.identifier.emailChang, RCC: rccchang@hku.hken_US
dc.identifier.authoritySo, KF=rp00329en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1016/j.jalz.2013.05.858-
dc.identifier.hkuros227136en_US
dc.identifier.volume9en_US
dc.identifier.issue4 suppl.-
dc.identifier.spageP435en_US
dc.identifier.epageP435en_US
dc.publisher.placeUnited States-
dc.customcontrol.immutablesml 140122-

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