File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Birth-related increase in intracolonic hydrogen gas and nitric oxide as indicator of host-microbial interactions

TitleBirth-related increase in intracolonic hydrogen gas and nitric oxide as indicator of host-microbial interactions
Authors
Issue Date2005
Citation
Allergy: European Journal of Allergy and Clinical Immunology, 2005, v. 60 n. 3, p. 396-400 How to Cite?
AbstractBackground: Bacterial colonization of the intestine early in life might have implications for allergy development. We studied early host-bacterial interactions in the gut by simultaneous measurements of hydrogen gas (H 2) and faecal short chain fatty acid pattern (SCFAs), i.e. bacterial products, as well as of nitric oxide (NO), a marker of mucosal immune activation. Methods: A novel minimally invasive technique was used for repeated measurements of luminal colonic H2 and NO in 32 healthy newborn infants delivered vaginally or by Caesarean section. Luminal gas was sampled and analysed at five occasions: immediately after birth, day 1, days 3-5, 1 and 5-6 months after birth. Results: Colonic H2, NO and faecal SCFAs were undetectable at birth. The H2 and SCFAs appeared within 24 h and continued to increase during the 6 months follow-up. Nitric oxide remained very low until 3-5 days after birth at which time it markedly increased. In some apparently healthy infants NO transiently reached levels similar to those seen in adults with inflammatory bowel disease. Conclusion: Intracolonic measurements of H2 and NO may be useful to monitor the developmental colonization process as well as mucosal responses. Copyright © Blackwell Munksgaard 2005.
Persistent Identifierhttp://hdl.handle.net/10722/192693
ISSN
2015 Impact Factor: 6.335
2015 SCImago Journal Rankings: 3.048
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSobko, Ten_US
dc.contributor.authorNorman, Men_US
dc.contributor.authorNorin, Een_US
dc.contributor.authorGustafsson, LEen_US
dc.contributor.authorLundberg, JOen_US
dc.date.accessioned2013-11-20T04:55:58Z-
dc.date.available2013-11-20T04:55:58Z-
dc.date.issued2005en_US
dc.identifier.citationAllergy: European Journal of Allergy and Clinical Immunology, 2005, v. 60 n. 3, p. 396-400en_US
dc.identifier.issn0105-4538en_US
dc.identifier.urihttp://hdl.handle.net/10722/192693-
dc.description.abstractBackground: Bacterial colonization of the intestine early in life might have implications for allergy development. We studied early host-bacterial interactions in the gut by simultaneous measurements of hydrogen gas (H 2) and faecal short chain fatty acid pattern (SCFAs), i.e. bacterial products, as well as of nitric oxide (NO), a marker of mucosal immune activation. Methods: A novel minimally invasive technique was used for repeated measurements of luminal colonic H2 and NO in 32 healthy newborn infants delivered vaginally or by Caesarean section. Luminal gas was sampled and analysed at five occasions: immediately after birth, day 1, days 3-5, 1 and 5-6 months after birth. Results: Colonic H2, NO and faecal SCFAs were undetectable at birth. The H2 and SCFAs appeared within 24 h and continued to increase during the 6 months follow-up. Nitric oxide remained very low until 3-5 days after birth at which time it markedly increased. In some apparently healthy infants NO transiently reached levels similar to those seen in adults with inflammatory bowel disease. Conclusion: Intracolonic measurements of H2 and NO may be useful to monitor the developmental colonization process as well as mucosal responses. Copyright © Blackwell Munksgaard 2005.en_US
dc.languageengen_US
dc.relation.ispartofAllergy: European Journal of Allergy and Clinical Immunologyen_US
dc.titleBirth-related increase in intracolonic hydrogen gas and nitric oxide as indicator of host-microbial interactionsen_US
dc.typeArticleen_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1398-9995.2005.00737.xen_US
dc.identifier.pmid15679729-
dc.identifier.scopuseid_2-s2.0-14344266293en_US
dc.identifier.volume60en_US
dc.identifier.issue3en_US
dc.identifier.spage396en_US
dc.identifier.epage400en_US
dc.identifier.isiWOS:000226639200020-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats