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Article: Bronchiolitis obliterans following lung transplantation

TitleBronchiolitis obliterans following lung transplantation
Authors
Issue Date2006
Citation
European Journal of Cardio-thoracic Surgery, 2006, v. 30 n. 6, p. 846-851 How to Cite?
AbstractBronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent studies suggest that immune injury is the main pathogenic event in small airway obliteration and the development of BOS. Early detection of BOS is possible as well as essential because prompt initiation of treatment may halt the progress of the disease and the development of chronic graft failure. Current treatment of BOS is disappointing despite advances in surgical techniques and improvements in immunosuppressive therapies. Therefore, a clear understanding of the pathogenesis of BOS plays a major role in the search for new and effective therapeutic strategies for better long-term survival and quality of life after lung transplantation. © 2006.
Persistent Identifierhttp://hdl.handle.net/10722/192663
ISSN
2015 Impact Factor: 2.803
2015 SCImago Journal Rankings: 1.568
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorAl-Githmi, Ien_US
dc.contributor.authorBatawil, Nen_US
dc.contributor.authorShigemura, Nen_US
dc.contributor.authorHsin, Men_US
dc.contributor.authorlee, TWen_US
dc.contributor.authorHe, G-Wen_US
dc.contributor.authorYim, Aen_US
dc.date.accessioned2013-11-20T04:54:58Z-
dc.date.available2013-11-20T04:54:58Z-
dc.date.issued2006en_US
dc.identifier.citationEuropean Journal of Cardio-thoracic Surgery, 2006, v. 30 n. 6, p. 846-851en_US
dc.identifier.issn1010-7940en_US
dc.identifier.urihttp://hdl.handle.net/10722/192663-
dc.description.abstractBronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent studies suggest that immune injury is the main pathogenic event in small airway obliteration and the development of BOS. Early detection of BOS is possible as well as essential because prompt initiation of treatment may halt the progress of the disease and the development of chronic graft failure. Current treatment of BOS is disappointing despite advances in surgical techniques and improvements in immunosuppressive therapies. Therefore, a clear understanding of the pathogenesis of BOS plays a major role in the search for new and effective therapeutic strategies for better long-term survival and quality of life after lung transplantation. © 2006.en_US
dc.languageengen_US
dc.relation.ispartofEuropean Journal of Cardio-thoracic Surgeryen_US
dc.titleBronchiolitis obliterans following lung transplantationen_US
dc.typeArticleen_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ejcts.2006.09.027en_US
dc.identifier.pmid17055283-
dc.identifier.scopuseid_2-s2.0-33751037266en_US
dc.identifier.volume30en_US
dc.identifier.issue6en_US
dc.identifier.spage846en_US
dc.identifier.epage851en_US
dc.identifier.isiWOS:000242904800007-

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