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Conference Paper: Diffusion-weighted resting-state functional MRI at 3T

TitleDiffusion-weighted resting-state functional MRI at 3T
Authors
Issue Date2013
PublisherInternational Society for Magnetic Resonance in Medicine (ISMRM).
Citation
The 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 3273 How to Cite?
AbstractResting-state functional MRI (rsfMRI) has emerged as a valuable become an increasingly important tool for mapping inter and intra-hemispheric connectivity in normal and diseased brains. To date, most rsfMRI studies have used T2*-weighted gradient-echo (GE) for the benefit of sensitivity. Theoretically, spin-echo (SE) provides better spatial specificity due to the elimination of static dephasing around macro-vessels. At 3T, the benefit however is limited because of a nearly equal share of undesired intravascular (IV) and well-localized extravascular (EV) contribution from microvasculature. Diffusion gradients induce velocity-dependent phase shifts and thus reduce signal from blood due to inhomogeneous velocities within vessel and presence of vessels with different orientations in a pixel. In this study, we aimed to investigate rsfMRI connectivity at 3T using diffusion-weighted (DW) SE to eliminate IV effect from large vessels. By using interleaving non-DW and DW acquisition, we identified default mode networks with similar but different pattern, spatially and spectrally. (Abstract by ISMRM)
DescriptionElectronic Poster Session: Functional MRI (neuro) - Resting State Connectivity: Methods
Persistent Identifierhttp://hdl.handle.net/10722/191643
ISSN

 

DC FieldValueLanguage
dc.contributor.authorCheng, JSen_US
dc.contributor.authorZhou, IYen_US
dc.contributor.authorGuo, Hen_US
dc.contributor.authorGao, PPen_US
dc.contributor.authorChan, RWen_US
dc.contributor.authorChan, Qen_US
dc.contributor.authorMak, HKFen_US
dc.contributor.authorKhong, PLen_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2013-10-15T07:14:50Z-
dc.date.available2013-10-15T07:14:50Z-
dc.date.issued2013en_US
dc.identifier.citationThe 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 3273en_US
dc.identifier.issn1557-3672-
dc.identifier.urihttp://hdl.handle.net/10722/191643-
dc.descriptionElectronic Poster Session: Functional MRI (neuro) - Resting State Connectivity: Methods-
dc.description.abstractResting-state functional MRI (rsfMRI) has emerged as a valuable become an increasingly important tool for mapping inter and intra-hemispheric connectivity in normal and diseased brains. To date, most rsfMRI studies have used T2*-weighted gradient-echo (GE) for the benefit of sensitivity. Theoretically, spin-echo (SE) provides better spatial specificity due to the elimination of static dephasing around macro-vessels. At 3T, the benefit however is limited because of a nearly equal share of undesired intravascular (IV) and well-localized extravascular (EV) contribution from microvasculature. Diffusion gradients induce velocity-dependent phase shifts and thus reduce signal from blood due to inhomogeneous velocities within vessel and presence of vessels with different orientations in a pixel. In this study, we aimed to investigate rsfMRI connectivity at 3T using diffusion-weighted (DW) SE to eliminate IV effect from large vessels. By using interleaving non-DW and DW acquisition, we identified default mode networks with similar but different pattern, spatially and spectrally. (Abstract by ISMRM)-
dc.languageengen_US
dc.publisherInternational Society for Magnetic Resonance in Medicine (ISMRM).-
dc.relation.ispartofSociety of Magnetic Resonance in Medicine Proceedingsen_US
dc.titleDiffusion-weighted resting-state functional MRI at 3Ten_US
dc.typeConference_Paperen_US
dc.identifier.emailZhou, IY: iriszhou@eee.hku.hken_US
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_US
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hk-
dc.identifier.authorityZhou, IY=rp01739en_US
dc.identifier.authorityKhong, PL=rp00467en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros226022en_US
dc.identifier.volume21-
dc.identifier.spage3273en_US
dc.identifier.epage3273en_US
dc.publisher.placeUnited Statesen_US

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