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Conference Paper: Brain development in preterm and term neonates assessed by white matter model of diffusion kurtosis imaging with tract-based spatial statistics analysis

TitleBrain development in preterm and term neonates assessed by white matter model of diffusion kurtosis imaging with tract-based spatial statistics analysis
Authors
Issue Date2013
PublisherISMRM.
Citation
The 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 0795 How to Cite?
AbstractThe purpose of this study was to investigate the white matter changes of diffusion parameters derived from white matter model of diffusion kurtosis imaging (DKI) in preterm and term neonates using tract-based spatial statistics (TBSS) analysis. In this study, 38 neonates with postmenstrual ages of 33 to 42 weeks were studied, including 19 preterm neonates and 19 term neonates. The results showed that significant increase of intra-axonal diffusivity without significant changes of axial diffusivity in extra-axonal space and radial diffusivity in extra-axonal space in genu of corpus callosum and body of corpus callosum, reflecting the increase of the alignment, caliber and number of axons. In posterior limb of internal capsule and splenium of corpus callosum, increased diffusion kurtosis or restriction were accompanied by the reduced diffusivity in radial direction. Such diffusivity and kurtosis analysis can be valuable to our understanding the white matter changes in intra-axon and extra-axon space during early development. (Abstract by ISMRM)
DescriptionScientific Session - Normal Developing Brain
Persistent Identifierhttp://hdl.handle.net/10722/191639
ISSN

 

DC FieldValueLanguage
dc.contributor.authorLi, XJen_US
dc.contributor.authorGao, Jen_US
dc.contributor.authorZhang, YMen_US
dc.contributor.authorLuo, Xen_US
dc.contributor.authorHan, JHen_US
dc.contributor.authorNiu, Gen_US
dc.contributor.authorWan, MXen_US
dc.contributor.authorWu, EXen_US
dc.contributor.authorYang, J-
dc.date.accessioned2013-10-15T07:14:48Z-
dc.date.available2013-10-15T07:14:48Z-
dc.date.issued2013en_US
dc.identifier.citationThe 21st Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2013), Salt Lake City, UT., 20-26 April 2013. In Society of Magnetic Resonance in Medicine Proceedings, 2013, v. 21, p. 0795en_US
dc.identifier.issn1557-3672-
dc.identifier.urihttp://hdl.handle.net/10722/191639-
dc.descriptionScientific Session - Normal Developing Brain-
dc.description.abstractThe purpose of this study was to investigate the white matter changes of diffusion parameters derived from white matter model of diffusion kurtosis imaging (DKI) in preterm and term neonates using tract-based spatial statistics (TBSS) analysis. In this study, 38 neonates with postmenstrual ages of 33 to 42 weeks were studied, including 19 preterm neonates and 19 term neonates. The results showed that significant increase of intra-axonal diffusivity without significant changes of axial diffusivity in extra-axonal space and radial diffusivity in extra-axonal space in genu of corpus callosum and body of corpus callosum, reflecting the increase of the alignment, caliber and number of axons. In posterior limb of internal capsule and splenium of corpus callosum, increased diffusion kurtosis or restriction were accompanied by the reduced diffusivity in radial direction. Such diffusivity and kurtosis analysis can be valuable to our understanding the white matter changes in intra-axon and extra-axon space during early development. (Abstract by ISMRM)-
dc.languageengen_US
dc.publisherISMRM.-
dc.relation.ispartofSociety of Magnetic Resonance in Medicine Proceedingsen_US
dc.titleBrain development in preterm and term neonates assessed by white matter model of diffusion kurtosis imaging with tract-based spatial statistics analysisen_US
dc.typeConference_Paperen_US
dc.identifier.emailWu, EX: ewu1@hkucc.hku.hken_US
dc.identifier.authorityWu, EX=rp00193en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros226003en_US
dc.identifier.volume21-
dc.identifier.spage0795en_US
dc.identifier.epage0795en_US
dc.publisher.placeUnited Statesen_US

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