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Article: Comparison of electroacupuncture in restrained and unrestrained rat models

TitleComparison of electroacupuncture in restrained and unrestrained rat models
Authors
Issue Date2013
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ecam/
Citation
Evidence-Based Complementary And Alternative Medicine, 2013, v. 2013 How to Cite?
AbstractAcupuncture and electroacupuncture (EA) are widely used to treat a variety of diseases including pain. In preclinical research, EA is usually applied by inserting acupuncture needles into the hindlimbs of rats restrained in small tubes or bags. This restrained model of EA not only causes stress-like behaviors but also is limited in stimulating locations and intensities. In 2004, a novel, unrestrained model of EA was introduced. However, these two EA methods have never been directly compared regarding their analgesic effects and other features such as stress. In the present study, we reported similar analgesic effects between restrained and unrestrained EA in rats of acute inflammatory pain induced by intraplantar injection of CFA. In addition, rats receiving unrestrained EA showed less significant stress-like behaviors and tolerated higher current intensity. These advantages suggest that this unrestrained EA method can replace the traditional restrained procedure with similar analgesic effects and allow for more choices of stimulating intensities and locations. © 2013 Haolin Zhang et al.
Persistent Identifierhttp://hdl.handle.net/10722/188665
ISSN
2015 Impact Factor: 1.931
2015 SCImago Journal Rankings: 0.615
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, Hen_US
dc.contributor.authorChen, Xen_US
dc.contributor.authorZhang, Cen_US
dc.contributor.authorZhang, Ren_US
dc.contributor.authorLao, Len_US
dc.contributor.authorWan, Yen_US
dc.contributor.authorYi, Men_US
dc.date.accessioned2013-09-03T04:10:58Z-
dc.date.available2013-09-03T04:10:58Z-
dc.date.issued2013en_US
dc.identifier.citationEvidence-Based Complementary And Alternative Medicine, 2013, v. 2013en_US
dc.identifier.issn1741-427Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/188665-
dc.description.abstractAcupuncture and electroacupuncture (EA) are widely used to treat a variety of diseases including pain. In preclinical research, EA is usually applied by inserting acupuncture needles into the hindlimbs of rats restrained in small tubes or bags. This restrained model of EA not only causes stress-like behaviors but also is limited in stimulating locations and intensities. In 2004, a novel, unrestrained model of EA was introduced. However, these two EA methods have never been directly compared regarding their analgesic effects and other features such as stress. In the present study, we reported similar analgesic effects between restrained and unrestrained EA in rats of acute inflammatory pain induced by intraplantar injection of CFA. In addition, rats receiving unrestrained EA showed less significant stress-like behaviors and tolerated higher current intensity. These advantages suggest that this unrestrained EA method can replace the traditional restrained procedure with similar analgesic effects and allow for more choices of stimulating intensities and locations. © 2013 Haolin Zhang et al.en_US
dc.languageengen_US
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/ecam/en_US
dc.relation.ispartofEvidence-based Complementary and Alternative Medicineen_US
dc.titleComparison of electroacupuncture in restrained and unrestrained rat modelsen_US
dc.typeArticleen_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.authorityLao, L=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1155/2013/404956en_US
dc.identifier.scopuseid_2-s2.0-84878683824en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84878683824&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume2013en_US
dc.identifier.isiWOS:000319572900001-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridZhang, H=54935552100en_US
dc.identifier.scopusauthoridChen, X=55758859200en_US
dc.identifier.scopusauthoridZhang, C=55759081100en_US
dc.identifier.scopusauthoridZhang, R=7404864527en_US
dc.identifier.scopusauthoridLao, L=7005681883en_US
dc.identifier.scopusauthoridWan, Y=7402417158en_US
dc.identifier.scopusauthoridYi, M=35790814500en_US

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