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- Publisher Website: 10.1089/pho.2009.2511
- Scopus: eid_2-s2.0-77953949583
- PMID: 19860569
- WOS: WOS:000278707900006
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Article: Validating a nonacupoint sham control for laser treatment of knee osteoarthritis
Title | Validating a nonacupoint sham control for laser treatment of knee osteoarthritis |
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Authors | |
Issue Date | 2010 |
Publisher | Mary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/lms |
Citation | Photomedicine And Laser Surgery, 2010, v. 28 n. 3, p. 351-356 How to Cite? |
Abstract | Objective: The goals of the present study were to evaluate the effect and safety of combined 10.6 μm and 650 nm laser acupuncture-moxibustion on patients with knee osteoarthritis (OA) and to validate a nonacupoint sham control for assessing the effect of point specificity on the treatment. Materials and Methods: A randomized, sham-controlled clinical trial was conducted in an outpatient clinical setting on patients with knee OA (n = 40). Laser irradiation was performed on acupoint Dubi (ST35) and a sham point three times a week for 4 wk. Outcome measurements were performed at baseline and at wk 2 and 4 using Western Ontario and McMaster Universities' Osteoarthritis Index (WOMAC). Results: At the 2-wk assessment, i.e., after 6 treatments, improvement in the WOMAC pain score of the acupoint group was significantly greater than that of the control group (49.21% vs. 11.99%, respectively; p = 0.021). However, there were no significant differences between the two groups in the WOMAC physical function score (p = 0.129) or joint stiffness score (p = 0.705). No side effects were found during the trial. Conclusions: Combined 10.6-μm-650-nm laser acupuncture-moxibustion on acupoint ST35 is safe to use and was effective after 2-wk treatment, but not at the 4-wk assessment, in relieving knee OA pain compared to a nonacupoint sham control. A larger clinical trial to verify our findings is warranted. © Copyright 2010, Mary Ann Liebert, Inc.. |
Persistent Identifier | http://hdl.handle.net/10722/188623 |
ISSN | 2020 Impact Factor: 2.796 2020 SCImago Journal Rankings: 0.431 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhao, L | en_US |
dc.contributor.author | Shen, X | en_US |
dc.contributor.author | Cheng, K | en_US |
dc.contributor.author | Deng, H | en_US |
dc.contributor.author | Ding, G | en_US |
dc.contributor.author | Tan, M | en_US |
dc.contributor.author | Lao, L | en_US |
dc.date.accessioned | 2013-09-03T04:10:41Z | - |
dc.date.available | 2013-09-03T04:10:41Z | - |
dc.date.issued | 2010 | en_US |
dc.identifier.citation | Photomedicine And Laser Surgery, 2010, v. 28 n. 3, p. 351-356 | en_US |
dc.identifier.issn | 1549-5418 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/188623 | - |
dc.description.abstract | Objective: The goals of the present study were to evaluate the effect and safety of combined 10.6 μm and 650 nm laser acupuncture-moxibustion on patients with knee osteoarthritis (OA) and to validate a nonacupoint sham control for assessing the effect of point specificity on the treatment. Materials and Methods: A randomized, sham-controlled clinical trial was conducted in an outpatient clinical setting on patients with knee OA (n = 40). Laser irradiation was performed on acupoint Dubi (ST35) and a sham point three times a week for 4 wk. Outcome measurements were performed at baseline and at wk 2 and 4 using Western Ontario and McMaster Universities' Osteoarthritis Index (WOMAC). Results: At the 2-wk assessment, i.e., after 6 treatments, improvement in the WOMAC pain score of the acupoint group was significantly greater than that of the control group (49.21% vs. 11.99%, respectively; p = 0.021). However, there were no significant differences between the two groups in the WOMAC physical function score (p = 0.129) or joint stiffness score (p = 0.705). No side effects were found during the trial. Conclusions: Combined 10.6-μm-650-nm laser acupuncture-moxibustion on acupoint ST35 is safe to use and was effective after 2-wk treatment, but not at the 4-wk assessment, in relieving knee OA pain compared to a nonacupoint sham control. A larger clinical trial to verify our findings is warranted. © Copyright 2010, Mary Ann Liebert, Inc.. | en_US |
dc.language | eng | en_US |
dc.publisher | Mary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/lms | en_US |
dc.relation.ispartof | Photomedicine and Laser Surgery | en_US |
dc.subject.mesh | Acupuncture Therapy | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Combined Modality Therapy | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Intention To Treat Analysis | en_US |
dc.subject.mesh | Laser Therapy - Methods | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Moxibustion | en_US |
dc.subject.mesh | Osteoarthritis, Knee - Therapy | en_US |
dc.subject.mesh | Recovery Of Function | en_US |
dc.title | Validating a nonacupoint sham control for laser treatment of knee osteoarthritis | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lao, L: lxlao1@hku.hk | en_US |
dc.identifier.authority | Lao, L=rp01784 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1089/pho.2009.2511 | en_US |
dc.identifier.pmid | 19860569 | - |
dc.identifier.scopus | eid_2-s2.0-77953949583 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-77953949583&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 28 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 351 | en_US |
dc.identifier.epage | 356 | en_US |
dc.identifier.isi | WOS:000278707900006 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Zhao, L=55493563400 | en_US |
dc.identifier.scopusauthorid | Shen, X=7402721090 | en_US |
dc.identifier.scopusauthorid | Cheng, K=7402998034 | en_US |
dc.identifier.scopusauthorid | Deng, H=14059741900 | en_US |
dc.identifier.scopusauthorid | Ding, G=7201791850 | en_US |
dc.identifier.scopusauthorid | Tan, M=55127194900 | en_US |
dc.identifier.scopusauthorid | Lao, L=7005681883 | en_US |
dc.identifier.issnl | 1549-5418 | - |