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Article: Validating a nonacupoint sham control for laser treatment of knee osteoarthritis

TitleValidating a nonacupoint sham control for laser treatment of knee osteoarthritis
Authors
Issue Date2010
PublisherMary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/lms
Citation
Photomedicine And Laser Surgery, 2010, v. 28 n. 3, p. 351-356 How to Cite?
AbstractObjective: The goals of the present study were to evaluate the effect and safety of combined 10.6 μm and 650 nm laser acupuncture-moxibustion on patients with knee osteoarthritis (OA) and to validate a nonacupoint sham control for assessing the effect of point specificity on the treatment. Materials and Methods: A randomized, sham-controlled clinical trial was conducted in an outpatient clinical setting on patients with knee OA (n = 40). Laser irradiation was performed on acupoint Dubi (ST35) and a sham point three times a week for 4 wk. Outcome measurements were performed at baseline and at wk 2 and 4 using Western Ontario and McMaster Universities' Osteoarthritis Index (WOMAC). Results: At the 2-wk assessment, i.e., after 6 treatments, improvement in the WOMAC pain score of the acupoint group was significantly greater than that of the control group (49.21% vs. 11.99%, respectively; p = 0.021). However, there were no significant differences between the two groups in the WOMAC physical function score (p = 0.129) or joint stiffness score (p = 0.705). No side effects were found during the trial. Conclusions: Combined 10.6-μm-650-nm laser acupuncture-moxibustion on acupoint ST35 is safe to use and was effective after 2-wk treatment, but not at the 4-wk assessment, in relieving knee OA pain compared to a nonacupoint sham control. A larger clinical trial to verify our findings is warranted. © Copyright 2010, Mary Ann Liebert, Inc..
Persistent Identifierhttp://hdl.handle.net/10722/188623
ISSN
2015 Impact Factor: 1.631
2015 SCImago Journal Rankings: 0.626
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhao, Len_US
dc.contributor.authorShen, Xen_US
dc.contributor.authorCheng, Ken_US
dc.contributor.authorDeng, Hen_US
dc.contributor.authorDing, Gen_US
dc.contributor.authorTan, Men_US
dc.contributor.authorLao, Len_US
dc.date.accessioned2013-09-03T04:10:41Z-
dc.date.available2013-09-03T04:10:41Z-
dc.date.issued2010en_US
dc.identifier.citationPhotomedicine And Laser Surgery, 2010, v. 28 n. 3, p. 351-356en_US
dc.identifier.issn1549-5418en_US
dc.identifier.urihttp://hdl.handle.net/10722/188623-
dc.description.abstractObjective: The goals of the present study were to evaluate the effect and safety of combined 10.6 μm and 650 nm laser acupuncture-moxibustion on patients with knee osteoarthritis (OA) and to validate a nonacupoint sham control for assessing the effect of point specificity on the treatment. Materials and Methods: A randomized, sham-controlled clinical trial was conducted in an outpatient clinical setting on patients with knee OA (n = 40). Laser irradiation was performed on acupoint Dubi (ST35) and a sham point three times a week for 4 wk. Outcome measurements were performed at baseline and at wk 2 and 4 using Western Ontario and McMaster Universities' Osteoarthritis Index (WOMAC). Results: At the 2-wk assessment, i.e., after 6 treatments, improvement in the WOMAC pain score of the acupoint group was significantly greater than that of the control group (49.21% vs. 11.99%, respectively; p = 0.021). However, there were no significant differences between the two groups in the WOMAC physical function score (p = 0.129) or joint stiffness score (p = 0.705). No side effects were found during the trial. Conclusions: Combined 10.6-μm-650-nm laser acupuncture-moxibustion on acupoint ST35 is safe to use and was effective after 2-wk treatment, but not at the 4-wk assessment, in relieving knee OA pain compared to a nonacupoint sham control. A larger clinical trial to verify our findings is warranted. © Copyright 2010, Mary Ann Liebert, Inc..en_US
dc.languageengen_US
dc.publisherMary Ann Liebert, Inc Publishers. The Journal's web site is located at http://www.liebertpub.com/lmsen_US
dc.relation.ispartofPhotomedicine and Laser Surgeryen_US
dc.subject.meshAcupuncture Therapyen_US
dc.subject.meshAgeden_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIntention To Treat Analysisen_US
dc.subject.meshLaser Therapy - Methodsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMoxibustionen_US
dc.subject.meshOsteoarthritis, Knee - Therapyen_US
dc.subject.meshRecovery Of Functionen_US
dc.titleValidating a nonacupoint sham control for laser treatment of knee osteoarthritisen_US
dc.typeArticleen_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.authorityLao, L=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1089/pho.2009.2511en_US
dc.identifier.pmid19860569-
dc.identifier.scopuseid_2-s2.0-77953949583en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-77953949583&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume28en_US
dc.identifier.issue3en_US
dc.identifier.spage351en_US
dc.identifier.epage356en_US
dc.identifier.isiWOS:000278707900006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridZhao, L=55493563400en_US
dc.identifier.scopusauthoridShen, X=7402721090en_US
dc.identifier.scopusauthoridCheng, K=7402998034en_US
dc.identifier.scopusauthoridDeng, H=14059741900en_US
dc.identifier.scopusauthoridDing, G=7201791850en_US
dc.identifier.scopusauthoridTan, M=55127194900en_US
dc.identifier.scopusauthoridLao, L=7005681883en_US

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