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Article: Effects of 650 nm - 10.6 μm combined laser acupuncture-moxibustion on knee osteoarthritis: A randomized, double-blinded and placebo-controlled clinical trial

TitleEffects of 650 nm - 10.6 μm combined laser acupuncture-moxibustion on knee osteoarthritis: A randomized, double-blinded and placebo-controlled clinical trial
Authors
KeywordsAcupuncture-Moxibustion Therapy
Clinical Trials
Laser
Osteoarthritis, Knee
Points, Dubi (St 35)
Randomized Controlled Trials
Issue Date2008
PublisherShanghai Research Institute of Acupuncture and Meridian, co-published with Springer. The Journal's web site is located at http://www.springer.com/medicine/complementary+%26+alternative+medicine/journal/11726
Citation
Journal Of Acupuncture And Tuina Science, 2008, v. 6 n. 5, p. 315-317 How to Cite?
AbstractObjective: To evaluate the effects of 650 nm - 10.6 μm combined laser in patients with knee Osteoarthritis (OA) and to determine whether the combined laser provides greater pain relief and improved function compared with red light. Methods: Forty-eight patients with knee OA were randomly allocated to two groups (24 per group), receiving 20 min irradiation with 650 nm - 10.6 μm combined laser or red light emitting diode respectively on point Dubi (ST 35) 3 times a week for the first course (2 weeks) and twice a week for the second one (4 weeks). The main outcome measures were WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores. In addition, patients' global assessment, adverse effects and validation of patient blinding were analyzed. Results: All the patients completed the first course, but 12 were lost during the second one. Due to the high dropout rate by the second course, only the data acquired from the first course could be analyzed. No differences of general data of patients and WOMAC scores were found in between-group comparison before treatment (P >0.05). The WOMAC scores of patients in both combined laser group and red light group reduced significantly compared to baseline by the end of the first course (P < 0.01). There were no significant differences on the reduction rate of WOMAC scores between two groups (P > 0.05). Neither the patients' global assessment nor the dropout rate showed statistical differences between two groups (P > 0.05). There was no difference between two groups in patients correctly guessing the treatment assignment (P > 0.05). There was no significant difference in the reduction rate of WOMAC scores and the patients' global assessment between patients who guessed their assignment (P > 0.05). Conclusion: Both combined laser and red light irradiation are beneficial to patients with knee OA. But as the statistical indifferences between two groups, the authors can't conclude from this study whether the combined laser is more effective. © Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag GmbH 2008.
Persistent Identifierhttp://hdl.handle.net/10722/188606
ISSN
2015 SCImago Journal Rankings: 0.216
References

 

DC FieldValueLanguage
dc.contributor.authorShen, XYen_US
dc.contributor.authorDing, GHen_US
dc.contributor.authorWu, Fen_US
dc.contributor.authorWang, LZen_US
dc.contributor.authorZhao, Len_US
dc.contributor.authorWang, Men_US
dc.contributor.authorLao, LXen_US
dc.date.accessioned2013-09-03T04:10:33Z-
dc.date.available2013-09-03T04:10:33Z-
dc.date.issued2008en_US
dc.identifier.citationJournal Of Acupuncture And Tuina Science, 2008, v. 6 n. 5, p. 315-317en_US
dc.identifier.issn1672-3597en_US
dc.identifier.urihttp://hdl.handle.net/10722/188606-
dc.description.abstractObjective: To evaluate the effects of 650 nm - 10.6 μm combined laser in patients with knee Osteoarthritis (OA) and to determine whether the combined laser provides greater pain relief and improved function compared with red light. Methods: Forty-eight patients with knee OA were randomly allocated to two groups (24 per group), receiving 20 min irradiation with 650 nm - 10.6 μm combined laser or red light emitting diode respectively on point Dubi (ST 35) 3 times a week for the first course (2 weeks) and twice a week for the second one (4 weeks). The main outcome measures were WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores. In addition, patients' global assessment, adverse effects and validation of patient blinding were analyzed. Results: All the patients completed the first course, but 12 were lost during the second one. Due to the high dropout rate by the second course, only the data acquired from the first course could be analyzed. No differences of general data of patients and WOMAC scores were found in between-group comparison before treatment (P >0.05). The WOMAC scores of patients in both combined laser group and red light group reduced significantly compared to baseline by the end of the first course (P < 0.01). There were no significant differences on the reduction rate of WOMAC scores between two groups (P > 0.05). Neither the patients' global assessment nor the dropout rate showed statistical differences between two groups (P > 0.05). There was no difference between two groups in patients correctly guessing the treatment assignment (P > 0.05). There was no significant difference in the reduction rate of WOMAC scores and the patients' global assessment between patients who guessed their assignment (P > 0.05). Conclusion: Both combined laser and red light irradiation are beneficial to patients with knee OA. But as the statistical indifferences between two groups, the authors can't conclude from this study whether the combined laser is more effective. © Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag GmbH 2008.en_US
dc.languageengen_US
dc.publisherShanghai Research Institute of Acupuncture and Meridian, co-published with Springer. The Journal's web site is located at http://www.springer.com/medicine/complementary+%26+alternative+medicine/journal/11726en_US
dc.relation.ispartofJournal of Acupuncture and Tuina Scienceen_US
dc.subjectAcupuncture-Moxibustion Therapyen_US
dc.subjectClinical Trialsen_US
dc.subjectLaseren_US
dc.subjectOsteoarthritis, Kneeen_US
dc.subjectPoints, Dubi (St 35)en_US
dc.subjectRandomized Controlled Trialsen_US
dc.titleEffects of 650 nm - 10.6 μm combined laser acupuncture-moxibustion on knee osteoarthritis: A randomized, double-blinded and placebo-controlled clinical trialen_US
dc.typeArticleen_US
dc.identifier.emailLao, LX: lxlao1@hku.hken_US
dc.identifier.authorityLao, LX=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s11726-008-0315-6en_US
dc.identifier.scopuseid_2-s2.0-55649105878en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-55649105878&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume6en_US
dc.identifier.issue5en_US
dc.identifier.spage315en_US
dc.identifier.epage317en_US
dc.publisher.placeChinaen_US
dc.identifier.scopusauthoridShen, XY=7402721090en_US
dc.identifier.scopusauthoridDing, GH=7201791850en_US
dc.identifier.scopusauthoridWu, F=55700774500en_US
dc.identifier.scopusauthoridWang, LZ=55721285100en_US
dc.identifier.scopusauthoridZhao, L=55493563400en_US
dc.identifier.scopusauthoridWang, M=36702238700en_US
dc.identifier.scopusauthoridLao, LX=7005681883en_US

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