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Article: Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation

TitleMu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation
Authors
Issue Date2005
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainres
Citation
Brain Research, 2005, v. 1048 n. 1-2, p. 235-240 How to Cite?
AbstractPrevious studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifically decreases MOR and blocks EA anti-hyperalgesia. These data suggest that spinal MOR-containing neurons are involved in the processes by which EA produces anti-hyperalgesia. © 2005 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/188571
ISSN
2015 Impact Factor: 2.561
2015 SCImago Journal Rankings: 1.351
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, RXen_US
dc.contributor.authorWang, Len_US
dc.contributor.authorLiu, Ben_US
dc.contributor.authorQiao, JTen_US
dc.contributor.authorRen, Ken_US
dc.contributor.authorBerman, BMen_US
dc.contributor.authorLao, Len_US
dc.date.accessioned2013-09-03T04:10:20Z-
dc.date.available2013-09-03T04:10:20Z-
dc.date.issued2005en_US
dc.identifier.citationBrain Research, 2005, v. 1048 n. 1-2, p. 235-240en_US
dc.identifier.issn0006-8993en_US
dc.identifier.urihttp://hdl.handle.net/10722/188571-
dc.description.abstractPrevious studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifically decreases MOR and blocks EA anti-hyperalgesia. These data suggest that spinal MOR-containing neurons are involved in the processes by which EA produces anti-hyperalgesia. © 2005 Elsevier B.V. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/brainresen_US
dc.relation.ispartofBrain Researchen_US
dc.subject.meshAnalysis Of Varianceen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlotting, Western - Methodsen_US
dc.subject.meshElectroacupuncture - Methodsen_US
dc.subject.meshFreund's Adjuvant - Adverse Effectsen_US
dc.subject.meshHindlimb - Drug Effects - Innervationen_US
dc.subject.meshHyperalgesia - Etiology - Therapyen_US
dc.subject.meshImmunohistochemistry - Methodsen_US
dc.subject.meshInflammation - Chemically Induced - Complicationsen_US
dc.subject.meshLectins - Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshN-Glycosyl Hydrolasesen_US
dc.subject.meshNeurons - Metabolismen_US
dc.subject.meshOpioid Peptidesen_US
dc.subject.meshPain Measurement - Methodsen_US
dc.subject.meshRandom Allocationen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Sprague-Dawleyen_US
dc.subject.meshReaction Time - Drug Effectsen_US
dc.subject.meshReceptors, Opioid, Delta - Metabolismen_US
dc.subject.meshReceptors, Opioid, Mu - Metabolismen_US
dc.subject.meshRecombinant Fusion Proteins - Pharmacologyen_US
dc.subject.meshRibosome Inactivating Proteins, Type 1en_US
dc.subject.meshSkin - Drug Effects - Innervationen_US
dc.subject.meshSpinal Cord - Cytology - Drug Effects - Metabolismen_US
dc.subject.meshSubstance P - Metabolismen_US
dc.titleMu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammationen_US
dc.typeArticleen_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.authorityLao, L=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.brainres.2005.05.008en_US
dc.identifier.pmid15922310en_US
dc.identifier.scopuseid_2-s2.0-20444406071en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-20444406071&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume1048en_US
dc.identifier.issue1-2en_US
dc.identifier.spage235en_US
dc.identifier.epage240en_US
dc.identifier.isiWOS:000230259600028-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridZhang, RX=7404864527en_US
dc.identifier.scopusauthoridWang, L=9036448600en_US
dc.identifier.scopusauthoridLiu, B=55720712900en_US
dc.identifier.scopusauthoridQiao, JT=7103301572en_US
dc.identifier.scopusauthoridRen, K=7102272533en_US
dc.identifier.scopusauthoridBerman, BM=35458606800en_US
dc.identifier.scopusauthoridLao, L=7005681883en_US

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