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Article: The effect of electroacupuncture as an adjunct on cyclophosphamide-induced emesis in ferrets

TitleThe effect of electroacupuncture as an adjunct on cyclophosphamide-induced emesis in ferrets
Authors
Issue Date2003
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pharmbiochembeh
Citation
Pharmacology Biochemistry And Behavior, 2003, v. 74 n. 3, p. 691-699 How to Cite?
AbstractThe effect of electroacupuncture (EA) on cyclophosphamide-induced emesis in ferrets was studied at acupuncture point Neiguan (P6) with various electrical stimulation parameters (5-100 Hz, 1.5-3 V, 5-20 min, n=6/group). The combination therapy of EA (100 Hz, 1.5 V and 10 min) with the lower doses of ondansetron (0.04 mg/kg), droperidol (0.25 mg/kg) and metoclopramide (2.24 mg/kg) significantly reduced the total number of emetic episodes by 52%, 36% and 73%, respectively, as well as the number of emetic episodes in the first phase as compared to the sham acupuncture control (P<.01). These EA/drug combinations also showed a significant effect in preventing emesis as compared to either EA or drug alone (P<.05). The present study suggests that acupuncture may be useful as an adjunctive therapy in the treatment of chemotherapy-induced emesis. © 2002 Elsevier Science Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/188549
ISSN
2015 Impact Factor: 2.537
2015 SCImago Journal Rankings: 1.121
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLao, Len_US
dc.contributor.authorZhang, Gen_US
dc.contributor.authorWong, RHen_US
dc.contributor.authorCarter, AKen_US
dc.contributor.authorWynn, RLen_US
dc.contributor.authorBerman, BMen_US
dc.date.accessioned2013-09-03T04:10:13Z-
dc.date.available2013-09-03T04:10:13Z-
dc.date.issued2003en_US
dc.identifier.citationPharmacology Biochemistry And Behavior, 2003, v. 74 n. 3, p. 691-699en_US
dc.identifier.issn0091-3057en_US
dc.identifier.urihttp://hdl.handle.net/10722/188549-
dc.description.abstractThe effect of electroacupuncture (EA) on cyclophosphamide-induced emesis in ferrets was studied at acupuncture point Neiguan (P6) with various electrical stimulation parameters (5-100 Hz, 1.5-3 V, 5-20 min, n=6/group). The combination therapy of EA (100 Hz, 1.5 V and 10 min) with the lower doses of ondansetron (0.04 mg/kg), droperidol (0.25 mg/kg) and metoclopramide (2.24 mg/kg) significantly reduced the total number of emetic episodes by 52%, 36% and 73%, respectively, as well as the number of emetic episodes in the first phase as compared to the sham acupuncture control (P<.01). These EA/drug combinations also showed a significant effect in preventing emesis as compared to either EA or drug alone (P<.05). The present study suggests that acupuncture may be useful as an adjunctive therapy in the treatment of chemotherapy-induced emesis. © 2002 Elsevier Science Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/pharmbiochembehen_US
dc.relation.ispartofPharmacology Biochemistry and Behavioren_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntiemetics - Therapeutic Useen_US
dc.subject.meshCombined Modality Therapy - Methodsen_US
dc.subject.meshCyclophosphamide - Toxicityen_US
dc.subject.meshElectroacupuncture - Methodsen_US
dc.subject.meshFerretsen_US
dc.subject.meshMaleen_US
dc.subject.meshVomiting - Chemically Induced - Therapyen_US
dc.titleThe effect of electroacupuncture as an adjunct on cyclophosphamide-induced emesis in ferretsen_US
dc.typeArticleen_US
dc.identifier.emailLao, L: lxlao1@hku.hken_US
dc.identifier.authorityLao, L=rp01784en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0091-3057(02)01069-9en_US
dc.identifier.pmid12543236en_US
dc.identifier.scopuseid_2-s2.0-0037305787en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037305787&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume74en_US
dc.identifier.issue3en_US
dc.identifier.spage691en_US
dc.identifier.epage699en_US
dc.identifier.isiWOS:000180769400023-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLao, L=7005681883en_US
dc.identifier.scopusauthoridZhang, G=7405272323en_US
dc.identifier.scopusauthoridWong, RH=7402126848en_US
dc.identifier.scopusauthoridCarter, AK=16678419200en_US
dc.identifier.scopusauthoridWynn, RL=19537208500en_US
dc.identifier.scopusauthoridBerman, BM=35458606800en_US

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