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- Publisher Website: 10.1016/B978-0-08-097774-4.00339-9
- Scopus: eid_2-s2.0-84902568580
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Book Chapter: Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis
Title | Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis |
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Authors | |
Keywords | Antimony Chloroquine Ferrocene Gold Leishmaniasis |
Issue Date | 2013 |
Publisher | Elsevier |
Citation | Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis. In Pecoraro, VL & Hambley, TW (Eds.), Comprehensive inorganic chemistry II: from elements to applications (2nd ed.), v. 3, p. 975-986. Amsterdam: Elsevier, 2013 How to Cite? |
Abstract | Parasitic diseases such as malaria, trypanosomiasis, and leishmaniasis are major health problems in the tropical area. Most clinically used drugs are decades old and suffered from severe side effects, limited efficacy, and emergence of drug resistance. As an alternative, the application of metal complexes as potential antiparasitic agents appears to be a promising approach. In this chapter, the advantages of metal complexes for the potential treatment of parasitic diseases are described. Further study on the mechanism of action of these compounds may facilitate the development of new metallodrugs with higher efficacy. |
Description | V. 3 title: Bioinorganic Fundamentals and Applications: Metals in Natural Living Systems and Metals in Toxicology and Medicine |
Persistent Identifier | http://hdl.handle.net/10722/187411 |
ISBN |
DC Field | Value | Language |
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dc.contributor.author | Wang, X | en_US |
dc.contributor.author | Sun, H | en_US |
dc.date.accessioned | 2013-08-20T12:42:40Z | - |
dc.date.available | 2013-08-20T12:42:40Z | - |
dc.date.issued | 2013 | en_US |
dc.identifier.citation | Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis. In Pecoraro, VL & Hambley, TW (Eds.), Comprehensive inorganic chemistry II: from elements to applications (2nd ed.), v. 3, p. 975-986. Amsterdam: Elsevier, 2013 | en_US |
dc.identifier.isbn | 9780080965291 | - |
dc.identifier.uri | http://hdl.handle.net/10722/187411 | - |
dc.description | V. 3 title: Bioinorganic Fundamentals and Applications: Metals in Natural Living Systems and Metals in Toxicology and Medicine | - |
dc.description.abstract | Parasitic diseases such as malaria, trypanosomiasis, and leishmaniasis are major health problems in the tropical area. Most clinically used drugs are decades old and suffered from severe side effects, limited efficacy, and emergence of drug resistance. As an alternative, the application of metal complexes as potential antiparasitic agents appears to be a promising approach. In this chapter, the advantages of metal complexes for the potential treatment of parasitic diseases are described. Further study on the mechanism of action of these compounds may facilitate the development of new metallodrugs with higher efficacy. | - |
dc.language | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.ispartof | Comprehensive inorganic chemistry II: from elements to applications (2nd ed.) | - |
dc.subject | Antimony | - |
dc.subject | Chloroquine | - |
dc.subject | Ferrocene | - |
dc.subject | Gold | - |
dc.subject | Leishmaniasis | - |
dc.title | Metal Complexes in the Treatment of Tropical Diseases: Malaria, Trypanosomiasis, and Leishmaniasis | en_US |
dc.type | Book_Chapter | en_US |
dc.identifier.email | Sun, H: hsun@hku.hk | en_US |
dc.identifier.authority | Sun, H=rp00777 | en_US |
dc.identifier.doi | 10.1016/B978-0-08-097774-4.00339-9 | - |
dc.identifier.scopus | eid_2-s2.0-84902568580 | - |
dc.identifier.hkuros | 220763 | en_US |
dc.identifier.volume | 3 | en_US |
dc.identifier.spage | 975 | en_US |
dc.identifier.epage | 986 | en_US |
dc.publisher.place | Amsterdam | - |