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Conference Paper: Identification of candidate epigenetic markers for early detection of nasopharyngeal carcinoma

TitleIdentification of candidate epigenetic markers for early detection of nasopharyngeal carcinoma
Authors
KeywordsMedical sciences
Oncology
Issue Date2013
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8, suppl. 1, abstract no. 3555 How to Cite?
AbstractNasopharyngeal carcinoma (NPC) is a human malignancy that is particularly prevalent in Southern China and Southeast Asia, and is strongly related to Epstein-Barr virus (EBV) infection. Since early detection of NPC will greatly improve the overall survival, screening becomes important for early NPC diagnosis. In this study, the methylation sensitive-high resolution melting (MS-HRM) method was established for detection of promoter DNA methylation using a panel of five tumor suppressor genes (RASSF1A, WIF1, DAPK1, RARβ2, p16), which were top candidates selected from 13 genes that had been tested in seven NPC cell lines and one immortalized NP cell line and which, showed highly different methylation status between cancer and immortalized ...
DescriptionPoster Presentations - Novel Biomarkers: abstract no. 3555
Persistent Identifierhttp://hdl.handle.net/10722/186933
ISSN
2015 Impact Factor: 8.556
2015 SCImago Journal Rankings: 5.372
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYang, Xen_US
dc.contributor.authorSzeto, YYen_US
dc.contributor.authorCheng, Yen_US
dc.contributor.authorKwong, DLWen_US
dc.contributor.authorLung, MLen_US
dc.date.accessioned2013-08-20T12:25:03Z-
dc.date.available2013-08-20T12:25:03Z-
dc.date.issued2013en_US
dc.identifier.citationThe 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8, suppl. 1, abstract no. 3555en_US
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/186933-
dc.descriptionPoster Presentations - Novel Biomarkers: abstract no. 3555-
dc.description.abstractNasopharyngeal carcinoma (NPC) is a human malignancy that is particularly prevalent in Southern China and Southeast Asia, and is strongly related to Epstein-Barr virus (EBV) infection. Since early detection of NPC will greatly improve the overall survival, screening becomes important for early NPC diagnosis. In this study, the methylation sensitive-high resolution melting (MS-HRM) method was established for detection of promoter DNA methylation using a panel of five tumor suppressor genes (RASSF1A, WIF1, DAPK1, RARβ2, p16), which were top candidates selected from 13 genes that had been tested in seven NPC cell lines and one immortalized NP cell line and which, showed highly different methylation status between cancer and immortalized ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/en_US
dc.relation.ispartofCancer Researchen_US
dc.subjectMedical sciences-
dc.subjectOncology-
dc.titleIdentification of candidate epigenetic markers for early detection of nasopharyngeal carcinomaen_US
dc.typeConference_Paperen_US
dc.identifier.emailSzeto, YY: cyyszeto@hku.hken_US
dc.identifier.emailCheng, Y: yuecheng@hku.hken_US
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_US
dc.identifier.emailLung, ML: mlilung@hku.hken_US
dc.identifier.authorityCheng, Y=rp01320en_US
dc.identifier.authorityKwong, DLW=rp00414en_US
dc.identifier.authorityLung, ML=rp00300en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1158/1538-7445.AM2013-3555-
dc.identifier.hkuros218581en_US
dc.identifier.hkuros219787-
dc.identifier.volume73-
dc.identifier.issue8, suppl. 1-
dc.identifier.isiWOS:000331220602260-
dc.publisher.placeUnited Statesen_US

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