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Conference Paper: Jaw Opening Changes after Radiotherapy for Nasopharyngeal Carcinoma

TitleJaw Opening Changes after Radiotherapy for Nasopharyngeal Carcinoma
Authors
KeywordsNeoplasia
Radiotherapy and TMJ and masticatory muscles
Issue Date2012
PublisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
The 6th International Association for Dental Research Pan-European Region Meeting (IADR/PER), Helsinki, Finland, 12-15 September 2012. In Journal of Dental Research, 2012, v. 91 n. Special Issue C: abstract no. 207 How to Cite?
AbstractObjectives: To investigate the changes of jaw opening in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods: Two hundred forty-two consecutive patients with newly diagnosed NPC were recruited. A jaw opening device plus daily jaw exercise instructions was prescribed to each patient. Maximum jaw opening at incisal region was measured at baseline and 2, 6 and 12 after radiotherapy. Multi-way repeated measures ANCOVA test was used to compare jaw opening changes over time and between groups (cancer staging, adjuvant chemotherapy and compliance with the jaw exercise). The level of significance was set to be 0.05. Results: A total of 212 patients completed the study. There was a significant reduction in mean jaw opening (P<0.05) from baseline (48.5±0.6 mm) to 2 months (46.6±0.6 mm) after radiotherapy. The mean jaw opening was significantly reduced further (P<0.05) at 6 months (42.1±0.7 mm) after radiotherapy but it remained stable at 12 months (42.1±0.8 mm) after treatment. Patients who received adjuvant chemotherapy exhibited significant smaller mean jaw opening after radiotherapy than patients who did not (P<0.05). Cancer staging and compliance with jaw exercise did not affect the jaw opening. Conclusions: Jaw opening was significantly reduced after radiotherapy for NPC and the use of adjuvant chemotherapy could further compromise the degree of jaw opening.
DescriptionPoster Presentation
Session 26: Oral Health Research
Persistent Identifierhttp://hdl.handle.net/10722/184869
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714

 

DC FieldValueLanguage
dc.contributor.authorPow, EHNen_US
dc.contributor.authorKwong, DLWen_US
dc.date.accessioned2013-07-15T10:15:43Z-
dc.date.available2013-07-15T10:15:43Z-
dc.date.issued2012en_US
dc.identifier.citationThe 6th International Association for Dental Research Pan-European Region Meeting (IADR/PER), Helsinki, Finland, 12-15 September 2012. In Journal of Dental Research, 2012, v. 91 n. Special Issue C: abstract no. 207en_US
dc.identifier.issn0022-0345-
dc.identifier.urihttp://hdl.handle.net/10722/184869-
dc.descriptionPoster Presentation-
dc.descriptionSession 26: Oral Health Research-
dc.description.abstractObjectives: To investigate the changes of jaw opening in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods: Two hundred forty-two consecutive patients with newly diagnosed NPC were recruited. A jaw opening device plus daily jaw exercise instructions was prescribed to each patient. Maximum jaw opening at incisal region was measured at baseline and 2, 6 and 12 after radiotherapy. Multi-way repeated measures ANCOVA test was used to compare jaw opening changes over time and between groups (cancer staging, adjuvant chemotherapy and compliance with the jaw exercise). The level of significance was set to be 0.05. Results: A total of 212 patients completed the study. There was a significant reduction in mean jaw opening (P<0.05) from baseline (48.5±0.6 mm) to 2 months (46.6±0.6 mm) after radiotherapy. The mean jaw opening was significantly reduced further (P<0.05) at 6 months (42.1±0.7 mm) after radiotherapy but it remained stable at 12 months (42.1±0.8 mm) after treatment. Patients who received adjuvant chemotherapy exhibited significant smaller mean jaw opening after radiotherapy than patients who did not (P<0.05). Cancer staging and compliance with jaw exercise did not affect the jaw opening. Conclusions: Jaw opening was significantly reduced after radiotherapy for NPC and the use of adjuvant chemotherapy could further compromise the degree of jaw opening.-
dc.languageengen_US
dc.publisherSage Publications, Inc. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925-
dc.relation.ispartofJournal of Dental Researchen_US
dc.rightsJournal of Dental Research. Copyright © Sage Publications, Inc.-
dc.subjectNeoplasia-
dc.subjectRadiotherapy and TMJ and masticatory muscles-
dc.titleJaw Opening Changes after Radiotherapy for Nasopharyngeal Carcinomaen_US
dc.typeConference_Paperen_US
dc.identifier.emailPow, EHN: ehnpow@hku.hken_US
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_US
dc.identifier.authorityPow, EHN=rp00030en_US
dc.identifier.authorityKwong, DLW=rp00414en_US
dc.identifier.hkuros215129en_US
dc.identifier.volume91en_US
dc.identifier.issueSpecial Issue C: abstract no. 207en_US
dc.publisher.placeUnited States-

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