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Article: Screening options for Down syndrome: How women choose in real clinical setting

TitleScreening options for Down syndrome: How women choose in real clinical setting
Authors
Issue Date2009
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
Citation
Prenatal Diagnosis, 2009, v. 29 n. 9, p. 852-856 How to Cite?
AbstractObjective: To study pregnant women's preference among various screening options for Down syndrome (DS) in routine clinical setting, and its potential association with women's demographic characteristics. Methods: Women aged 35 years and older carrying singleton pregnancy were offered a variety of screening tests for DS before 14 weeks of gestation. Their preference was confirmed by the test they actually underwent. The association between women's choice of test and a number of demographic characteristics was studied using multinomial regression. Results: Among 1967 eligible women, 619 opted for first-trimester screening test (FTS), 924 for partial integrated test (PIT), and 424 for full integrated test (FIT). Nulliparous women and working mothers were more likely to choose FTS and FIT. Women with history of subfertility were more likely to choose FIT. Women with family history of chromosomal abnormalities were more likely to choose FTS. The choice of screening test could be predicted for 49.9% of women using four demographic characteristics. Conclusions: Among older women of predominantly Chinese ethnicity, integrated test is a favorite alternative to FTS. Their choice of DS screening test can be predicted by their obstetric and socioeconomic characteristics. Many women show willingness to pay for a test with a lower false-positive rate. Copyright © 2009 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/184211
ISSN
2015 Impact Factor: 3.043
2015 SCImago Journal Rankings: 1.450
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLo, TKen_US
dc.contributor.authorLai, FKen_US
dc.contributor.authorLeung, WCen_US
dc.contributor.authorLau, WLen_US
dc.contributor.authorNg, LSen_US
dc.contributor.authorWong, WCen_US
dc.contributor.authorTam, SSen_US
dc.contributor.authorYee, YCen_US
dc.contributor.authorChoi, Hen_US
dc.contributor.authorLam, HSWen_US
dc.contributor.authorSham, ASYen_US
dc.contributor.authorTang, LCHen_US
dc.contributor.authorChin, RKHen_US
dc.date.accessioned2013-06-25T03:01:25Z-
dc.date.available2013-06-25T03:01:25Z-
dc.date.issued2009en_US
dc.identifier.citationPrenatal Diagnosis, 2009, v. 29 n. 9, p. 852-856en_US
dc.identifier.issn0197-3851en_US
dc.identifier.urihttp://hdl.handle.net/10722/184211-
dc.description.abstractObjective: To study pregnant women's preference among various screening options for Down syndrome (DS) in routine clinical setting, and its potential association with women's demographic characteristics. Methods: Women aged 35 years and older carrying singleton pregnancy were offered a variety of screening tests for DS before 14 weeks of gestation. Their preference was confirmed by the test they actually underwent. The association between women's choice of test and a number of demographic characteristics was studied using multinomial regression. Results: Among 1967 eligible women, 619 opted for first-trimester screening test (FTS), 924 for partial integrated test (PIT), and 424 for full integrated test (FIT). Nulliparous women and working mothers were more likely to choose FTS and FIT. Women with history of subfertility were more likely to choose FIT. Women with family history of chromosomal abnormalities were more likely to choose FTS. The choice of screening test could be predicted for 49.9% of women using four demographic characteristics. Conclusions: Among older women of predominantly Chinese ethnicity, integrated test is a favorite alternative to FTS. Their choice of DS screening test can be predicted by their obstetric and socioeconomic characteristics. Many women show willingness to pay for a test with a lower false-positive rate. Copyright © 2009 John Wiley & Sons, Ltd.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252en_US
dc.relation.ispartofPrenatal Diagnosisen_US
dc.subject.meshAdulten_US
dc.subject.meshDown Syndrome - Diagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHealth Knowledge, Attitudes, Practiceen_US
dc.subject.meshHumansen_US
dc.subject.meshMass Screening - Economics - Methods - Psychologyen_US
dc.subject.meshMaternal Ageen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPatient Preference - Economics - Statistics & Numerical Dataen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Trimester, Firsten_US
dc.subject.meshPrenatal Diagnosis - Economics - Methods - Psychologyen_US
dc.subject.meshReproductive Medicineen_US
dc.subject.meshSocioeconomic Factorsen_US
dc.titleScreening options for Down syndrome: How women choose in real clinical settingen_US
dc.typeArticleen_US
dc.identifier.emailTang, LCH: lchtang@hku.hken_US
dc.identifier.authorityTang, LCH=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/pd.2292en_US
dc.identifier.pmid19441088-
dc.identifier.scopuseid_2-s2.0-69749115670en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-69749115670&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume29en_US
dc.identifier.issue9en_US
dc.identifier.spage852en_US
dc.identifier.epage856en_US
dc.identifier.isiWOS:000269943500005-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLo, TK=7203076032en_US
dc.identifier.scopusauthoridLai, FK=24461966400en_US
dc.identifier.scopusauthoridLeung, WC=7201504435en_US
dc.identifier.scopusauthoridLau, WL=12142218500en_US
dc.identifier.scopusauthoridNg, LS=35311771500en_US
dc.identifier.scopusauthoridWong, WC=34979507500en_US
dc.identifier.scopusauthoridTam, SS=35312537000en_US
dc.identifier.scopusauthoridYee, YC=35312864300en_US
dc.identifier.scopusauthoridChoi, H=15047739500en_US
dc.identifier.scopusauthoridLam, HSW=16022602300en_US
dc.identifier.scopusauthoridSham, ASY=35312333800en_US
dc.identifier.scopusauthoridTang, LCH=7402081111en_US
dc.identifier.scopusauthoridChin, RKH=24358899900en_US

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