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Article: Effect of propranolol on human spermatozoal in vitro hamster ova penetration.

TitleEffect of propranolol on human spermatozoal in vitro hamster ova penetration.
Authors
Issue Date1984
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01485016.asp
Citation
Archives Of Andrology, 1984, v. 12 Suppl, p. 79-82 How to Cite?
AbstractThe effect of (D,L)-propranolol at various concentrations (3.4 X 10(-6) to 3.4 X 10(-3) M) on human spermatozoal motility and zona-free hamster ova penetration was studied in vitro. Propranolol, in 10(-4) M concentration, completely abolished the spermatozoal motility and hamster ova penetration. No significant effect was observed on the spermatozoal motility and the hamster ova penetration efficiency with concentrations of the agent as low as 3.4 X 10(-6) M. The blocking action of propranolol on the in vitro penetration of hamster ova appears to be a direct consequence of the depressive effect of this drug on spermatozoal motility.
Persistent Identifierhttp://hdl.handle.net/10722/184162
ISSN
2009 Impact Factor: 0.891

 

DC FieldValueLanguage
dc.contributor.authorChan, SYen_US
dc.contributor.authorTang, LCen_US
dc.contributor.authorChan, PHen_US
dc.date.accessioned2013-06-25T03:00:54Z-
dc.date.available2013-06-25T03:00:54Z-
dc.date.issued1984en_US
dc.identifier.citationArchives Of Andrology, 1984, v. 12 Suppl, p. 79-82en_US
dc.identifier.issn0148-5016en_US
dc.identifier.urihttp://hdl.handle.net/10722/184162-
dc.description.abstractThe effect of (D,L)-propranolol at various concentrations (3.4 X 10(-6) to 3.4 X 10(-3) M) on human spermatozoal motility and zona-free hamster ova penetration was studied in vitro. Propranolol, in 10(-4) M concentration, completely abolished the spermatozoal motility and hamster ova penetration. No significant effect was observed on the spermatozoal motility and the hamster ova penetration efficiency with concentrations of the agent as low as 3.4 X 10(-6) M. The blocking action of propranolol on the in vitro penetration of hamster ova appears to be a direct consequence of the depressive effect of this drug on spermatozoal motility.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01485016.aspen_US
dc.relation.ispartofArchives of Andrologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshFemaleen_US
dc.subject.meshFertilization In Vitro - Drug Effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPropranolol - Pharmacologyen_US
dc.subject.meshSperm Capacitation - Drug Effectsen_US
dc.subject.meshSperm-Ovum Interactions - Drug Effectsen_US
dc.titleEffect of propranolol on human spermatozoal in vitro hamster ova penetration.en_US
dc.typeArticleen_US
dc.identifier.emailTang, LC: lchtang@hku.hken_US
dc.identifier.authorityTang, LC=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid6535456en_US
dc.identifier.scopuseid_2-s2.0-0021731296en_US
dc.identifier.volume12 Supplen_US
dc.identifier.spage79en_US
dc.identifier.epage82en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, SY=7404255960en_US
dc.identifier.scopusauthoridTang, LC=7402081111en_US
dc.identifier.scopusauthoridChan, PH=7403497875en_US

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