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Article: Stimulation of the human spermatozoal fertilizing ability by dibutyryl 3',5'-CAMP and theophylline in vitro

TitleStimulation of the human spermatozoal fertilizing ability by dibutyryl 3',5'-CAMP and theophylline in vitro
Authors
Issue Date1983
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01485016.asp
Citation
Archives Of Andrology, 1983, v. 11 n. 1, p. 19-23 How to Cite?
AbstractThe stimulation of the human spermatozoal fertilizing ability by dibutyryl 3',5'-CAMP (diCAMP) and theophylline in suspected fertile and subfertile semen samples was demonstrated with the zona-free hamster ova penetration test. The penetration rates for the untreated (control) fertile and subfertile samples were 30% and 17%, respectively. DiCAMP increased the penetration rates to 54% and 37% (with 5 mM diCAMP) and to 46% and 36% (with 10 mM diCAMP) in the fertile and subfertile samples, respectively; theophylline increased the penetration rates to 56% and 35% (with 10 mM theophylline) and to 49% and 42% (with 20 mM theophylline) in the fertile and subfertile samples, respectively. These results indicate that diCAMP and theophylline can affect the fertilizing ability of human spermatozoa in vitro.
Persistent Identifierhttp://hdl.handle.net/10722/184150
ISSN
2009 Impact Factor: 0.891
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, SYWen_US
dc.contributor.authorTang, LCHen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2013-06-25T03:00:46Z-
dc.date.available2013-06-25T03:00:46Z-
dc.date.issued1983en_US
dc.identifier.citationArchives Of Andrology, 1983, v. 11 n. 1, p. 19-23en_US
dc.identifier.issn0148-5016en_US
dc.identifier.urihttp://hdl.handle.net/10722/184150-
dc.description.abstractThe stimulation of the human spermatozoal fertilizing ability by dibutyryl 3',5'-CAMP (diCAMP) and theophylline in suspected fertile and subfertile semen samples was demonstrated with the zona-free hamster ova penetration test. The penetration rates for the untreated (control) fertile and subfertile samples were 30% and 17%, respectively. DiCAMP increased the penetration rates to 54% and 37% (with 5 mM diCAMP) and to 46% and 36% (with 10 mM diCAMP) in the fertile and subfertile samples, respectively; theophylline increased the penetration rates to 56% and 35% (with 10 mM theophylline) and to 49% and 42% (with 20 mM theophylline) in the fertile and subfertile samples, respectively. These results indicate that diCAMP and theophylline can affect the fertilizing ability of human spermatozoa in vitro.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01485016.aspen_US
dc.relation.ispartofArchives of Andrologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBucladesine - Pharmacologyen_US
dc.subject.meshCricetinaeen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfertility, Male - Physiopathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshSperm-Ovum Interactions - Drug Effectsen_US
dc.subject.meshSpermatozoa - Drug Effectsen_US
dc.subject.meshTheophylline - Pharmacologyen_US
dc.titleStimulation of the human spermatozoal fertilizing ability by dibutyryl 3',5'-CAMP and theophylline in vitroen_US
dc.typeArticleen_US
dc.identifier.emailTang, LCH: lchtang@hku.hken_US
dc.identifier.authorityTang, LCH=rp01756en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid6312907-
dc.identifier.scopuseid_2-s2.0-0020624036en_US
dc.identifier.volume11en_US
dc.identifier.issue1en_US
dc.identifier.spage19en_US
dc.identifier.epage23en_US
dc.identifier.isiWOS:A1983RA44300004-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US
dc.identifier.scopusauthoridTang, LCH=7402081111en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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